ライフサイエンスコーパス: sequence homology

1 share the same architecture on the basis of sequence homology.

2 SKI/SNO/DAC domain, despite lacking obvious sequence homology.

3 high structural similarity despite their low sequence homology.

4 tilis, SpaI, despite the lack of significant sequence homology.

5 the Holliday junctions to the boundaries of sequence homology.

6 oup was highly variable and not predicted by sequence homology.

7 or genes and estimate their likelihoods from sequence homology.

8 nnel analog) without sharing any significant sequence homology.

9 nuclease YbeY, even though they do not share sequence homology.

10 to four clusters based on gene structure and sequence homology.

11 tail genes even in the absence of detectable sequence homology.

12 r features, MFS transporters share only weak sequence homology.

13 humans on the basis of their high degree of sequence homology.

14 nt beta-galactosidase showed high amino acid sequence homology.

15 ors, respectively, despite their significant sequence homology.

16 ATX1-Like Copper Chaperone (CCH), share high sequence homology.

17 some annotations are solely on the basis of sequence homology.

18 an array of cell-surface receptors that lack sequence homology.

19 a melanogaster, and Mus musculus revealed no sequence homology.

20 ntiporter NhaA, despite having no detectable sequence homology.

21 AD51 paralogue genes have been identified by sequence homology.

22 ring transcription initiation despite little sequence homology.

23 fferent very long chain lengths despite high sequence homology.

24 fact that the human and rat forms share 99% sequence homology.

25 hibitor sensitivity profiles despite lacking sequence homology.

26 istance protein families, despite a very low sequence homology.

27 itiator, TbORC1/CDC6, has been identified by sequence homology.

28 d nature of their functional commonality and sequence homology.

29 factor-beta superfamily sharing 89% protein sequence homology.

30 gly than GC-rich duplexes, regardless of the sequence homology.

31 discrimination of miRNA sequences with high sequence homology.

32 discrimination of miRNA sequences with high sequence homology.

33 ow the efficiency of repair is influenced by sequence homology.

34 classified by their receptor specificity and sequence homology.

35 183, -96 and -182, is also a miR family with sequence homology.

36 lipid kinases, despite the absence of clear sequence homology.

37 ures are unknown, but they share significant sequence homologies.

38 termed SMASH, for short multiply aggregated sequence homologies.

39 were annotated as motility-related based on sequence homologies.

40 Despite low sequence homology (48.2%-77.3% similarity), all ortholog

41 Low sequence homology (88% average pairwise identity) and fr

42 re a family of proteins with no structure or sequence homology, able to elicit a sweet sensation in h

43 A nucleoprotein filaments efficiently locate sequence homology across genomic DNA remains unclear.

44 LlaBIII shares >95% amino acid sequence homology across its first three protein domains

45 Despite sequence homology across the PAR isoforms, discovery of

46 Based on sequence homology, AdPLA is part of a small family of ac

47 BESs were searched for sequence homology against known databases.

48 m the identification of short regions of DNA sequence homology, also known as microhomology, at chrom

49 Despite high sequence homology among different deer species, a fallow

50 Considering the high sequence homology among DNA of H. pylori isolated from s

51 roperties of short length, low abundance and sequence homology among family members, it is difficult

52 omoter using the following methodologies: 1) sequence homology among several mammalian species, 2) DN

53 Because of the substantial level of sequence homology among sodium channels, our data also i

54 However, sequence homology among them is limited.

55 Sequence homology among viruses and ability of T cells t

56 RFs) and does not require linkers, adaptors, sequence homology, amplification or mutation (domesticat

57 thermal denaturation, biochemical assays and sequence homology analysis all strongly support defects

58 Sequence homology analysis revealed a potential canonica

59 ue of the mouse Rosa26 locus through genomic sequence homology analysis.

60 conserved enhancers in the absence of overt sequence homologies and over extensive evolutionary dist

61 predict organismal metabolic networks using sequence homology and a global metabolic network constru

62 Sister chromatids provide near-perfect sequence homology and are therefore the preferred templa

63 2 cytotoxic factors exhibited 50% amino acid sequence homology and bound to the same receptor, they c

64 TssL and TssM share sequence homology and characteristics with two component

65 of M. silvestris and eukaryotic Tdms have no sequence homology and contrasting characteristics.

66 EF-P shares sequence homology and crystal structure with eIF5A, but

67 Sequence homology and domain modeling suggest that Teb1

68 EptC shares significant amino acid sequence homology and domain structure with the MukB pro

69 FcepsilonR1gamma and CD247 share high sequence homology and form disulphide-linked homodimers

70 genases, with which they share only moderate sequence homology and from which they are distinguished

71 he depupylase Dop share close structural and sequence homology and have a common evolutionary history

72 ve markedly different patterns of evolution; sequence homology and negative selection were highest in

73 or open pan-genomes and share generally high sequence homology and number of core genes including vir

74 Despite sharing up to 78% sequence homology and overlapping expression profiles in

75 We performed sequence homology and phylogenetic analyses, and carried

76 Sequence homology and phylogenetic analysis indicated th

77 prehensive systems-scale analysis of genomic sequence homology and phylogenetic relationships among C

78 immunoglobulin-like fold, despite sharing no sequence homology and possessing different disulfide lin

79 ase, where the synaptic joints either locate sequence homology and progress to a post-synaptic joint,

80 Based on sequence homology and secondary structure prediction, we

81 They can be divided in two classes based on sequence homology and the presence of an insertion withi

82 at this effect is largely independent of DNA sequence homology and thus cannot be explained by non-al

83 y to other profilins correlated with overall sequence homology, and 2 immunodominant epitope regions

84 like canonical Rap1 effectors despite little sequence homology, and disruption of the binding strongl

85 ubtle structural similarities independent of sequence homology appear to sustain operational equivale

86 e bat-associated viruses because of its high sequence homology (approximately 90% in most genes) to i

87 By sequence homology Aq793 is a member of the PcrA/UvrD/Rep

88 l set of gene expression data in addition to sequence homologies are instrumental in the assignment o

89 st that not all Pooideae grass epitopes with sequence homology are cross-reactive.

90 llowed differentiation of proteins with high sequence homology as evidenced by de novo sequencing of

91 Despite sequence homology at the active site and biophysical pro

92 In first step, sequence homology-based genetic analysis of a set of 50

93 A major limitation of sequence homology-based identification for highly diverg

94 The low levels of amino acid sequence homology between E3-19K proteins suggest that t

95 Given the high amino acid sequence homology between fish enzymes, a 3-D structure

96 In addition, sequence homology between frog and mammalian Cerberus is

97 Capitalizing on the complete sequence homology between human and mouse in the heparin

98 Despite the sequence homology between RON and MET receptor tyrosine

99 e and RRV proteins; we identified regions of sequence homology between RRV and enolase.

100 trategy that was based on the high degree of sequence homology between S1P(1) and S1P(2).

101 The unexpected nucleotide sequence homology between SLE patient-derived autoantibo

102 Thus, sequence homology between T cell epitopes of 2 self-prot

103 However, on the basis of sequence homology between the 5 Ebolavirus species, we h

104 ial collaboration in actin assembly, but low sequence homology between the Basic domains of Drosophil

105 The high sequence homology between the D3R and D2R, especially wi

106 tor has been challenging because of the high sequence homology between the D3R and the dopamine D2 re

107 These methods, which rely on sequence homology between the ends of DNA parts, have be

108 vidual antigenic regions correlated with the sequence homology between the MVA- and DNA Gag-encoded i

109 rved from bacteria to man, despite a lack of sequence homology between the resolvases.

110 ly, SNGD-mediated gene editing requires long-sequence homology between the target gene and repair tem

111 y, EigenTHREADER does not depend directly on sequence homology between the target protein and entries

112 Strong sequence homology between the three ORMDL genes and ORMD

113 : the similarity in action suggests that the sequence homology between the two compounds might have a

114 Despite the low sequence homology between the two enzymes (29% identity)

115 en co-expressed in COS-7 cells, despite high sequence homology between the two enzymes.

116 ne coupling subunits do not share an obvious sequence homology between the two transporter families.

117 Despite limited sequence homology between the vertebrate and Drosophila

118 ghly challenging owing to the glutamate-site sequence homology between these proteins.

119 hbor" serotype O55:H7 revealed a high degree sequence homology between these two serotypes.

120 esponses were rarely elicited when there was sequence homology between vaccine immunogen and endogeno

121 d that MdmX, an Mdm2 family member with high sequence homology, binds adenine nucleotides with simila

122 composed of several isoforms that share high sequence homology but differ in functional characteristi

123 tional modeling, we studied ORs sharing high sequence homology but with different response properties

124 ide bonds are quite diverse and share little sequence homology, but all contain a CXXC catalytic acti

125 (RecA-ssDNA) filament searches a genome for sequence homology by rapidly binding and unbinding doubl

126 d developed an acute HBV infection with 100% sequence homology, compared with HBV inoculum.

127 s from known antibody crystal structures and sequence homology comparison indicates that non-consensu

128 The confounding effects of sequence homology, complexity of competing cleavages and

129 ering, presence of H275Y mutation, and viral sequence homology confirmed nosocomial transmission of o

130 As predicted by sequence homology, CT189/190 are the two subunits of DNA

131 Evolutionary analysis and sequence homology data revealed P450 family blooms in oo

132 paya lines resistant to PRSV isolates in the sequence-homology-dependent manner have been developed i

133 Sequence homology diagrams were constructed to compare e

134 n of CER2 as a BAHD acyltransferase based on sequence homology does not fit with CER2 catalytic activ

135 Thus, despite limited sequence homology, Drosophila and vertebrate APCs exhibi

136 M2) are functional analogs, they have little sequence homology, except for a conserved HXXXW motif, w

137 pathogen specific with minimum interspecies sequence homology for the design of Flavivirus vaccines.

138 le identification of natural LHE proteins by sequence homology from genomic and metagenomic sequence

139 Despite significant sequence homologies, functional differences between the

140 putational approaches based, for example, on sequence homology, gene co-expression and phylogenetic p

141 While sequence homology has been a standard to annotate metabo

142 Sequence homology identified the pyridoxal phosphate-dep

143 Detailed analysis of sequence homology identifies canonical TIR motifs as wel

144 The notion that sequence homology implies functional similarity underlie

145 itope in the CH3 domain of hFc that has high sequence homology in all four hIgG isotypes (hIgG(1-4)),

146 , of which 3,761 are novel with little or no sequence homology in any existing databases.

147 or netrin-domain-containing proteins display sequence homology in structurally important regions of A

148 e virulent P18 strain shows a high degree of sequence homology in the bisegmented genome between the

149 The two transporters share 40% sequence homology in the C-terminal transmembrane region

150 rison of the resulting peptides showed large sequence homology in the phosphopeptides released by try

151 The six clones demonstrated some sequence homology in the region 2600-2605 and incorporat

152 B-cell receptors (BCRs) with a high level of sequence homology in the variable domains of the heavy a

153 Despite substantial sequence homology in their core domains, nTop1 and mitoc

154 PLN and SLN have significant sequence homology in their transmembrane regions, sugges

155 identify analogous folds where little or no sequence homology information is.

156 that makes use of both network topology and sequence homology information, based upon the observatio

157 Inference of sequence homology is inherently an evolutionary question

158 This low sequence homology is the result of the inclusion of diso

159 ften persists throughout evolution even when sequence homology is undetectable, As macromolecules can

160 on of two DNA sequences that contain limited sequence homology, lie in inverted orientation, and are

161 , bacterial and mammalian PPATs share little sequence homology, making the enzyme a potential target

162 tionic amino acid transporters (CATs) due to sequence homology, may represent system c.

163 We notice significant sequence homology of AIM2(PYD) with the hydrophobic patc

164 conservation of neural expression and strong sequence homology of all CORL proteins suggests that thi

165 Despite the high sequence homology of the two domains, a network of large

166 Our data indicate that due to linear sequence homology, part of the MOG35-55-specific T cell

167 Gene sequence homology predicts that the sioxanthin biosynthe

168 ufficient coverage (<20x read depth) or high sequence homology (pseudogenes) are complemented by ampl

169 cue model for SV with breakpoints located in sequence homology regions.

170 Is of Colias and the silkmoth, but no intron sequence homology remains.

171 tion tools RepeatMasker and Censor depend on sequence homology search tools such as cross_match and B

172 For allergen identification protein sequencing, homology search and mass spectrometry were a

173 Sequence homology searches were performed to extend ZU5-

174 and are classified into four groups based on sequence homology (SEPT2, SEPT3, SEPT6, and SEPT7 groups

175 f these proteins, which share no discernible sequence homology, share a striking structural similarit

176 t to the Toll/IL-1R domain of TLR10 with low sequence homology, substantial differences were observed

177 Despite a lack of sequence homology, the genes are aligned in a head-to-ta

178 Consistent with the sequence homology, the GK subunits adopt the same overal

179 two enzymes share approximately 50% protein sequence homology, the membrane topology of VKOR is stil

180 Thus, despite low overall sequence homology, the production of infectious virus is

181 Although the RSKs have a high degree of sequence homology, their functional differences in cance

182 Although calbindin and S100B have a low sequence homology, they seem to activate IMPase-1 in a s

183 Dscam and vertebrate Pcdh proteins share no sequence homology, they seem to underlie similar strateg

184 AChR subtypes (M1-M5) share a high degree of sequence homology, they show pronounced differences in G

185 Furthermore, PHF2 shares significant sequence homology throughout the entire region, includin

186 SSGP-71 proteins lack sequence homologies to other proteins, but their structu

187 TP0326, the sole protein in T. pallidum with sequence homology to a Gram-negative OMP, belongs to the

188 es significant structural similarity but not sequence homology to a group of enzymes that bind to and

189 Sequence homology to a putative yeast thiamine (vitamin

190 Sequence homology to A1cf, the RNA-binding subunit of th

191 he green alga Chlamydomonas reinhardtii with sequence homology to animal cryptochromes and (6-4) phot

192 Gp1.7 is unusual in that it has no sequence homology to any known nucleotide kinase, it has

193 TcpF has no apparent sequence homology to any known protein.

194 gene, RteC, did not have primary amino acid sequence homology to any known proteins in the databases

195 d executor type R genes show no considerable sequence homology to any known R genes.

196 d executor type R genes show no considerable sequence homology to any known R genes.

197 proteins (LipA and LipB) that had amino acid sequence homology to bacterial adhesins and structural h

198 Furthermore, this domain has been shown by sequence homology to be present in all bacterial L-serin

199 identified, but human FIZZ2 has significant sequence homology to both rodent FIZZ2 (59%) and FIZZ1 (

200 CLDs have high degrees of sequence homology to cathelin, a protein isolated from p

201 (CD99L2) is a membrane protein with moderate sequence homology to CD99, which initiates cell aggregat

202 bout half of the components of the TCPM show sequence homology to components of the previously analys

203 ator of Cdk1 and Cdk2 that has no amino acid sequence homology to cyclins, are sterile and display me

204 EnvD showed strong sequence homology to dienelactone hydrolases from other

205 f approximately 70 amino acids and have high sequence homology to each other (>85% identity).

206 ces cerevisiae MTase Yjr129c, which displays sequence homology to FAM86A, is a functional FAM86A orth

207 ar domains KL1 and KL2, each of which shares sequence homology to glycosyl hydrolases.

208 a class of vertebrate proteins that exhibits sequence homology to innexins, the invertebrate gap junc

209 embers of a tick protein family bearing high sequence homology to Japanin are also likely to bind cho

210 ammaherpesvirus 68 (MHV68) ORF73 (mLANA) has sequence homology to Kaposi's sarcoma-associated herpesv

211 affinity M. sexta GABA transporter with high sequence homology to known mammalian GABA transporters,

212 r short (2-100 amino acids) peptides with no sequence homology to known proteins.

213 One of these miRNAs, miR-J8, has seed sequence homology to members of the cellular miR-17/20/1

214 segment of the LRRK2 kinase domain based on sequence homology to mixed-lineage kinases.

215 SynCaK displays significant sequence homology to MthK, a calcium-dependent potassium

216 Based on its cytoskeletal association and sequence homology to myelin P2 (FABP8), it has been sugg

217 ng the Crenarchaeota branch, and bear little sequence homology to other DNA polymerase families.

218 This region has no sequence homology to other known fibrinogen binding prot

219 al virus proteins display very low levels of sequence homology to other proteins listed in the public

220 ew major allergen was isolated, which showed sequence homology to peritrophins, which contain chitin-

221 Based on sequence homology to pilins in Gram-negative bacteria, C

222 SdbA shows low sequence homology to previously identified oxidoreductas

223 r analysis" yielded heavy chains with little sequence homology to previously identified VRC01 class h

224 he hidden Markov model library that provides sequence homology to SCOP structural domains remains unc

225 hiseptica, plrS, the product of which shares sequence homology to several NtrY-family sensor kinases

226 potassium conductance domains that show high sequence homology to the bacterial TrkA family of K(+) t

227 rminal domain (AP7C) that exhibits imperfect sequence homology to the C subclass of the intracellular

228 nsmembrane-helix (6-TM) domain, which has no sequence homology to the canonical tetrameric K(+) chann

229 e, and the core herpesvirus genes had strong sequence homology to the corresponding KSHV genes.

230 92 aa protein that contains a domain showing sequence homology to the glycosyl hydrolase motif in the

231 to-inhibitory domain within Snf2h that bears sequence homology to the H4 tail, abolishes the linker-l

232 These proteins have sequence homology to the N-terminal domain (NTD) of the

233 Despite close sequence homology to the protease cathepsin L, the silic

234 associated with metabolosomes (PduL) has no sequence homology to the PTAC ubiquitous among fermentat

235 cludes a rhodanese-fold in accordance to its sequence homology to the rhodanese family of sulfurtrans

236 cific sgRNA is not uniquely defined by exact sequence homology to the target site, thus unintended of

237 elanogaster alpha7 (Dalpha7) has the closest sequence homology to the vertebrate alpha7 subunit and i

238 Despite showing no primary sequence homology to TNF family cytokines, UL141 binds t

239 Based on sequence homology to TNF-alpha, now a total of 19 member

240 Despite previous failure in detecting any sequence homology to ubiquitin, the folded state was det

241 des a single-pass transmembrane protein with sequence homology to vertebrate Cysteine-rich transmembr

242 s capable of recognizing extremely divergent sequence homology, we identified a MYRF protein domain d

243 Based on sequence homology, we identified a single M. polymorpha

244 Based on sequence homology, we identify IPLA-1 as the closest C.

245 proteins of these viruses show the greatest sequence homology, we tested hyperimmune antisera prepar

246 A strong genome colinearity and sequence homology were observed between MneRV2 and RRV26

247 eyi (Hd-CDT), which share limited amino acid sequence homology, were directly compared.

248 omyces lactis Hsv2, which shares significant sequence homologies with its three Saccharomyces cerevis

249 BM2 shares little sequence homology with AM2, except for a conserved HxxxW

250 NM; and (iii) the LnmJ-SH domain, sharing no sequence homology with any other enzymes catalyzing C-S

251 ciparum SSB (Pf-SSB) shares a high degree of sequence homology with bacterial SSB proteins but differ

252 protease and signaling inhibitor TIKI shares sequence homology with bacterial TraB/PrgY proteins, inh

253 se, but further work revealed that it shared sequence homology with beta-lactamase/metallo-beta-lacta

254 system, we discovered an adhiron that shared sequence homology with C3 and abolished C3-induced prolo

255 One adhiron (A6) was found to have a sequence homology with C3 and studied further.

256 r protein KIAA0157, which shares significant sequence homology with CCDC98.

257 ClsC has sequence homology with ClsA and ClsB, which all belong t

258 They often shared sequence homology with co-expressed genes and contained

259 They share a high sequence homology with cyclotides but are biosynthetical

260 d3 is presumed to be palmitoylated, based on sequence homology with Drd2, but the functional attribut

261 he two O. tsutsugamushi isolates shared >99% sequence homology with each other, reflecting the consis

262 The HLA-DR-presented GNS peptide has marked sequence homology with epitopes from sulfatase proteins

263 LsbB shares significant sequence homology with five other leaderless bacteriocin

264 rhodopsins from cryptophyte algae show close sequence homology with haloarchaeal rhodopsin proton pum

265 cus contains more than 50 genes sharing high sequence homology with hexose transporters in Saccharomy

266 ne viral miRNA, miR-K12-11, shares 100% seed sequence homology with hsa-miR-155, an oncogenic human m

267 S27, UL33, and UL78, which present important sequence homology with human chemokine receptors.

268 Despite limited sequence homology with human GLTP, we recently showed th

269 ingolipids between membranes and has limited sequence homology with human glycolipid transfer protein

270 the deduced Cq-IGFBP was shown to share high sequence homology with IGFBP family members from both in

271 Although it has low amino acid sequence homology with known 2-oxoglutarate-dependent di

272 acterized protein, Vp1659, which shares some sequence homology with LcrV from Yersinia.

273 ound ubiquitin ligase that bears significant sequence homology with mammalian Hrd1 and mediates stero

274 ntial to viral transcription and that shares sequence homology with members of the paramyxoviruses an

275 (DENV1 to -4), which share a high degree of sequence homology with one another.

276 erotypes (DENV1 to -4) which share 67 to 75% sequence homology with one another.

277 of the S1 helix, as a consequence of its low sequence homology with other Kv family members.

278 S2 shares no sequence homology with other retroviral factors known to

279 NS1 C-terminal residues 305-311, which share sequence homology with Plg residues 590-597.

280 Hp0267 shares no sequence homology with previously characterized ADDs, ye

281 we demonstrate that NUCKS1 shares extensive sequence homology with RAD51AP1 (RAD51 associated protei

282 , an essential initiation factor, having 21% sequence homology with RatA.

283 ICMT has no discernible sequence homology with soluble methyltransferases, and a

284 vel ORFs, which we name cylc-1 and -2, share sequence homology with stathmins and encode small, very

285 (H1N1) virus exhibits hemagglutinin protein sequence homology with the 1918 pandemic influenza virus

286 imensional models of MdtB and MdtC, based on sequence homology with the AcrB transporter, also suppor

287 It exhibits strong sequence homology with the bacteriophage T7 gene 4 prote

288 Remarkably, Us3 displays no sequence homology with the cellular kinase Akt, yet dire

289 Restriction enzymes share little or no sequence homology with the exception of isoschizomers, o

290 nfected with HCV that had more than 95% NS5B sequence homology with the HCV strains of the 3 case pat

291 erminal domain (C domain) shares significant sequence homology with the OmpA-like family of peptidogl

292 d, and P4 proteins of WMoV exhibited limited sequence homology with the orthologous proteins of other

293 PLR1) was identified in Arabidopsis based on sequence homology with the protein in yeast.

294 e inserted, as the position is determined by sequence homology with the recombination primers.

295 Although StnA has no significant sequence homology with the reported alpha/beta-fold hydr

296 Class C methylases share significant sequence homology with the RS enzyme, HemN, and may bind

297 The endogenous protein has 88.0% sequence homology with the theoretically predicted Gly m

298 acy by up to 40% for species which have high sequence homology within their genus.

299 eptors ERalpha and ERbeta share considerable sequence homology yet exert opposite effects on breast c

300 alcium channel, has three isoforms with >65% sequence homology, yet the isoforms differ in their func