ライフサイエンスコーパス: sequence identity

1 ene segments (PB2, PB1, NA, MP, and NS; >98% sequence identity).

2 1-like enzyme from Arabidopsis thaliana (60% sequence identity).

3 e named species that share 99% 16S rRNA gene sequence identity.

4 rganization they display just 31% amino acid sequence identity.

5 YP51A and CYP51B, which share 59% amino acid sequence identity.

6 ompared with a polyhedrin with less than 10% sequence identity.

7 ies comparable to alignments based on actual sequence identity.

8 roteins of the two viruses sharing about 80% sequence identity.

9 d transposases annotated in GenBank with 80% sequence identity.

10 sequence identity, and northern bobwhite 97% sequence identity.

11 clustered in different families based on 90% sequence identity.

12 Nase III-like enzymes sharing 75% amino acid sequence identity.

13 losely-related paralogs with >75% amino acid sequence identity.

14 an 96% sequence coverage and more than 99.8% sequence identity.

15 tructure while tandem MS was used to confirm sequence identity.

16 hich often result in paralog genes with high sequence identity.

17 le is known about Kgp, which shares only 27% sequence identity.

18 ared structure despite low abundance and low sequence identity.

19 rties compared with gpASNase1, despite a 70% sequence identity.

20 e most divergent family members sharing <15% sequence identity.

21 nverting enzyme 2, sharing approximately 50% sequence identity.

22 ty and structural homology, they exhibit low sequence identity.

23 e fragments demonstrating very low levels of sequence identity.

24 iddle-domain across species, despite lack of sequence identity.

25 ic infection clusters, each having 99.8-100% sequence identity.

26 ipase-like proteins that share less than 20% sequence identity.

27 lic localization and at least 70% amino acid sequence identity.

28 gh they share between 90% and 99% amino acid sequence identity.

29 haC1, to which ChaC2 shows approximately 50% sequence identity.

30 miniviral genome and shares only 50% overall sequence identity.

31 pFI, although they lack significant pairwise sequence identity.

32 er despite the fact that they share only 21% sequence identity.

33 EpsL, with which it also shares virtually no sequence identity.

34 ing the same fold for two sequences with low sequence identity.

35 units of ~109 kb in size that have 97.7% DNA sequence identity.

36 her clinical EKC isolates showed nearly 100% sequence identity.

37 rthologs is more similar despite the lowered sequence identity.

38 for optimal function, despite possessing low sequence identity.

39 CCL-conserved motif but share low amino acid sequence identity.

40 es at the level of 90%, 50% and 30% pairwise sequence identity.

41 The encoded proteins share ~85% amino acid sequence identity.

42 ionally closely linked EF-Ts only shares 55% sequence identity.

43 -3CL(pro) and PEDV 3CL(pro) share only 45.4% sequence identity.

44 erent TrpB homologues with as little as 57 % sequence identity.

45 viruses (HIV), tend to share high amino acid sequence identity.

46 parate transcriptional programs despite high sequence identity.

47 ty to its T2S ortholog GspH, despite minimal sequence identity.

48 osome and the mRNA substrate given their low sequence identities.

49 l RNase architectures despite possessing low sequence identities.

50 AgTG3 has a similar degree of sequence identity (~30%) to both human Factor XIII (FXII

51 c parameters despite a low level of pairwise sequence identity (39-72%).

52 Blo t 21 has moderate sequence identity (40.7%) to Blo t 5 and low to moderate

53 ArsB and ArsC, which share a high sequence identity (71%), produce alkylresorcinols and al

54 ver dopamine D2 receptor (D2R), despite high sequence identity (78% in the transmembrane domain).

55 ce protein A (OspA, beta-sheet) to have high sequence identity (80 and 77%, respectively) with engine

56 High sequence identity (98%) between the genes encoding Fcgam

57 These metrics include (i) average protein sequence identity across all orthologs shared by two gen

58 of-thumb that proteins with as little as 30% sequence identity adopt the same fold.

59 V-1 and HIV-2 proteases share just 38 to 49% sequence identity, all critical structural features of p

60 Us), which are clustered on the basis of DNA sequence identity alone, are the most commonly used micr

61 APRs are less conserved than average sequence identity among closely related homologues (>/=8

62 ally share only approximately 50% amino acid sequence identity among different donors.

63 Despite the high sequence identity among different SAA isoforms, not all

64 nt) but APRs are more conserved than average sequence identity among homologues that have at least 50

65 less than 10,000 y ago, have high levels of sequence identity among subgenomes that mask the effects

66 occur in regions that share 100% amino-acid sequence identity among the 3 isoforms.

67 The high sequence identity among these available sources may prec

68 ork within the Drosophila genus, we analyzed sequence identities and similarities of clock protein ho

69 These enzymes share high sequence identity and catalyze 4-pro-(R)-hydride transfe

70 When both base sequence identity and chemical probing reactivities were

71 ette, which we call DC4, had a high level of sequence identity and cluster together phylogenetically.

72 RPC4 and TRPC5 proteins share 65% amino acid sequence identity and form Ca(2+)-permeable nonselective

73 After careful correction for sequence identity and GC content, we predict approximate

74 and actin because the two proteins share low sequence identity and have distinct cellular roles.

75 es, with one gene in the pair having greater sequence identity and higher alignment scores with respe

76 re we surveyed the frequency of variation in sequence identity and length at CSB 2 amongst human mito

77 ilizes fixed-backbone design to optimize the sequence identity and nucleobase conformations of an RNA

78 fication of Proteins) domains with up to 70% sequence identity and present all similarities among the

79 ne mammalian Nav channel isoforms share high sequence identity and remain recalcitrant to high-resolu

80 of 131 submissions (79%) had >99% nucleotide sequence identity and resistance mutation concordance, c

81 I by incorporating information from both the sequence identity and secondary structures.

82 One BLV miRNA, BLV-miR-B4, shares partial sequence identity and shared common targets with the hos

83 and a distinct shape of relationship between sequence identity and structure similarity.

84 The integrases share only 59% amino acid sequence identity and the attP sites have fewer than 50%

85 we demonstrate a global correlation between sequence identity and the binding of small molecules wit

86 Due to their high levels of sequence identity and the existence of many polymorphic

87 ee families according to their percentage of sequence identity and their pharmacological properties.

88 y homologous but evolved with widely varying sequence identity and thermodynamic stability.

89 Although they share a high degree of sequence identity and thus similarity in structure, many

90 Despite RalA and RalB sharing 82% sequence identity and utilization of shared effector pro

91 Human and zebrafish CFTR share 55% sequence identity, and 42 of the 46 cystic-fibrosis-caus

92 study in humans due to the large size, high sequence identity, and mosaic nature of segmental duplic

93 chicken myoglobin, Japanese quail showed 98% sequence identity, and northern bobwhite 97% sequence id

94 used only with parents of sufficient overall sequence identity, and provides no control over the resu

95 ToxB homologs, or for any protein with >30% sequence identity, and therefore what underlies activity

96 Despite possessing a high degree of sequence identity, Ang1 and Ang2 have distinct functiona

97 Rrt6 shows only limited sequence identity ( approximately 15%) to known p24 prot

98 models built on template structures over 50% sequence identity are within 2.9 A of the experimental s

99 milar to the yeast homolog Ipk2, despite 17% sequence identity, as well as the active site architectu

100 for the BRD4 bromodomains that have over 90% sequence identity at the acetyl-lysine binding site.

101 simple tandem duplication of defensin7 with sequence identity at the junction, suggesting nonallelic

102 orm those that use PSSM (PSSMStr) as well as sequence identity based representation (IDStr).

103 bes the specific parameters for a nucleotide-sequence-identity-based method of organizing the viral s

104 divergent, with 77% and 87% mean amino acid sequence identities between East Asian and non-Asian gro

105 lytic infection by the phage is dependent on sequence identity between CRISPR spacers and the target

106 Despite the high degree of amino acid sequence identity between family members, ASCTs function

107 characterized by a short N terminus and high sequence identity between human and mouse.

108 The high sequence identity between JPV-BH and JPV-LW suggests tha

109 ough three simple mutations despite only 26% sequence identity between native human and E. coli DHFRs

110 eys, it has been suggested that lowering the sequence identity between neighboring domains is one of

111 l complementation correlates with amino acid sequence identity between orthologs, but varies consider

112 ss rate of MR however drops quickly when the sequence identity between query and templates is reduced

113 However, low sequence identity between receptors, conformational flex

114 (HIV-1) capsid, although there is negligible sequence identity between RSV and HIV-1 CA in the region

115 cleotide polymorphisms, although the protein sequence identity between strains exceeds 90% on average

116 lso display extreme divergence in amino acid sequence identity between STs (i.e., 59%-61% median iden

117 or toxicity testing is often reliant on high sequence identity between the human proteins and their a

118 A3(OB) and A6, despite only ~40% amino acid sequence identity between the OB-folds of A3 and A6.

119 ed using the template structure, the percent sequence identity between the template and target, and t

120 results highlight several key differences in sequence identity between these two steps, complement kn

121 The average nucleotide sequence identity between two genomes can be used for pr

122 g and homology modeling, especially when the sequence identity between two proteins under considerati

123 Because of their very high sequence identity, biochemical studies done on H-Ras hav

124 pite their evolutionary distance and limited sequence identity, both ClpXP and the proteasome share a

125 Despite a 97% sequence identity, both isozymes differ largely in their

126 Despite low sequence identity, both yeast and mammalian CTDs share a

127 cent design of proteins displaying very high sequence identities but different 3D structure allows th

128 forms in the same individual displaying high sequence identities but large functional differences.

129 eins, including proteins with high levels of sequence identity but different folds, are exceptions to

130 ir subunit proteins FlgG and FlgE having 39% sequence identity, but show distinct mechanical properti

131 Two MmsF homologs sharing over 60% sequence identity, but showing no apparent impact on par

132 ficity so that only molecules with very high sequence identity can form cross-beta-sheet structures o

133 metabolic pathway, the homologous SnoN (38% sequence identity) catalyzes an epimerization step at th

134 Using >4 kb length and >95% sequence identity criteria, we analyzed of the genome-wi

135 Despite this lack of sequence identity, cross-species transgenesis has identi

136 ntifies the relative contributions of parent sequence identity, crossover locations, and protein fold

137 Despite their high amino acid sequence identities, each enzyme produced a different pr

138 These features include regions of perfect sequence identity encompassing 700 bp at the hotspot cor

139 tionally caution against interpreting genome sequence identity for this pathogen as proof of a direct

140 A particular situation is the high sequence identity found between the Copia25 sequences of

141 istance between NAHR substrate elements, DNA sequence identity (fraction matching), GC content, and c

142 2 TMHs), size (from 183 to 420 residues) and sequence identity (from 15% to 70%), the method improves

143 yltransferase, the closely related RdmB (52% sequence identity) from the rhodomycin pathways is an at

144 sting of 5,696 unique microbial OTUs (at 97% sequenced identity) from 47 bacterial and three archaeal

145 In vitro, these enzymes, which share 78% sequence identity, generate distinct products from their

146 their complex structure, large size and high sequence identity, genetic variation within LCR22s among

147 ptor templates and homologous templates with sequence identity >30% were excluded.

148 in paralogs having up to approximately 99.6% sequence identity, identify small gene-disruptive deleti

149 nce databases such as UniProt, with pairwise sequence identities in the range of ~40-60%.

150 us, Acinetobacter, but instead shows limited sequence identity in its N-terminal half with fungal DSD

151 rent deficit might arise from the erosion of sequence identity in numts originating from rapidly evol

152 PRRSV isolates (sharing 55 to 99% nucleotide sequence identity in ORF5).

153 ansferases (PKMTs) sharing approximately 80% sequence identity in their catalytic domains.

154 hly related RalA and RalB small GTPases (82% sequence identity) in pancreatic ductal adenocarcinoma (

155 Surprisingly, RVD sequence identity influences both the overall stability

156 In this study, we evaluate whether sequence identity, InterPro or Catalytic Site Atlas sequ

157 and encode an integrase, and attachment site sequence identity is carefully noted; therefore, the dat

158 effect on fusion triggering, suggesting that sequence identity is not critical for this function.

159 quence similarity and demonstrated that ~80% sequence identity is sufficient for enrichment.

160 s (LCRs) >10 kb in size and sharing >97% DNA sequence identity, is responsible for the majority of re

161 2,890 operational taxonomic units (OTUs; 97% sequence identity level) including members of all eukary

162 ticidal toxin-like proteins, despite the low sequence identity (<10%).

163 However, this protein had only low sequence identity (<25%) to the lipoate ligases of demon

164 BH3 binding grooves showed that, despite low sequence identity, M11 has structural similarities to Bc

165 deomycetes, and despite their modest primary sequence identity, many are perceived by the cognate tom

166 refolding of tandem repeats, independent of sequence identity, more than half of all molecules trans

167 omorphic pairs, displaying increasingly high-sequence identity (namely, 30%, 77%, and 88%), but diffe

168 We find that reducing sequence identity not only decreases the formation of do

169 Based on the sequence identities of enzymes and activity determinatio

170 Do the amino acid sequence identities of residues that make contact across

171 ion between the MMP substrate preference and sequence identity of 50-57 discontinuous residues surrou

172 S1 is a SLAMF6 homolog with an amino acid sequence identity of 97% to SLAMF6 in its ligand-binding

173 from 45% to 81% and primarily depend on the sequence identity of aligned target sequences and templa

174 However, overall sequence identity of ARSK with other human sulfatases is

175 lates of the epidemic period had a very high sequence identity of at least 99.9% and formed a monophy

176 Together, our study shows that DNA sequence identity of genomic binding sites modulates GR

177 Finally, despite the near sequence identity of MtrA in M. smegmatis and M. tubercu

178 Given the near sequence identity of rRNA genes within a species, it is

179 same surface patch on Blo t 1, as well as of sequence identity of surface-exposed residues, suggests

180 ermined by peptide length in addition to the sequence identity of the MHCI-bound peptide.

181 The sequence identity of the miRNA provides the specificity

182 The close sequence identity of WW2 with WW1 and WW3 residues that

183 t efficient algorithms to optimize the local sequence identity or the nearest-neighbor approximation

184 Despite limited sequence identity, PilE is structurally similar to Neiss

185 Both clusters contain palindromes with high sequence identity, presumably maintained by gene convers

186 Analysis of sequence identity profiles and phylogenic relationships

187 ve a puzzling drop in accuracy in the 40-60% sequence identity range, the so-called 'BRaliBase Dent'.

188 ss results in a 16 kb cluster that shares no sequence identity, regulation or organizational principl

189 1 to 49% nucleotide and 40 to 70% amino acid sequence identities, respectively, with other grapevine

190 ent could be reliably predicted based on the sequence identity seen in the original BLOSUM62 alignmen

191 and, despite these proteins sharing very low sequence identity, structure-based phylogenetic analysis

192 AE1.1 and Bn-FAE1.2 promoters possess strong sequence identity suggesting that transcriptional contro

193 teins due to difficulties in recognizing low-sequence identity templates with a similar fold to the t

194 d fungal cell cycle regulators share no more sequence identity than non-homologous proteins.

195 Here we show, despite 90% sequence identity, that Danio rerio and Mus musculus alp

196 Despite sharing only 30% sequence identity, the molecules resemble one another cl

197 Despite 48% sequence identity, the proteins have distinct activities

198 Despite high sequence identity, the three proteins showed distinct di

199 Despite sharing little sequence identity, the toxin domains are structurally si

200 spite their different functions and only 23% sequence identity, the two proteins have very similar ov

201 As yeast duplicates diverge beyond 70% sequence identity, their ability to compensate for each

202 te the high structural similarity with 64.3% sequence identity, their responses to Gd@C82(OH)22 were

203 for naturally occurring neighbours with low sequence identity, these transient misfolds disappear mu

204 ugh both proteins share about 90% amino acid sequence identity, they exhibit different open probabili

205 Despite their high sequence identity, they show different sensitivities to

206 such depositions, identifying them by a 95% sequence identity threshold, performs analysis of their

207 nate (CHM) hydratase (GalB), which has a 12% sequence identity to a previously identified CHM hydrata

208 al inner spore membrane protein and exhibits sequence identity to A subunits of the spore's nutrient

209 stly unnamed and not linked by 16S rRNA-gene sequence identity to a taxonomic scheme.

210 truncatula (MtHPP) was based on the highest sequence identity to A. thaliana enzyme.

211 ltiple calmodulin (CaM) isoforms of variable sequence identity to animal CaM suggested an additional

212 At 88-90% mtCOI sequence identity to Aphelinidae wasps, we concluded tha

213 , five genes were found with ~50% amino acid sequence identity to Arabidopsis tryptophan aminotransfe

214 Cat r 1 ( approximately 91% sequence identity to Bet v 7) was cloned from a cDNA lib

215 Many CAZymes share insufficient sequence identity to characterized proteins from other m

216 e hemagglutinin cleavage site which had 100% sequence identity to chicken 28S rRNA, suggesting that t

217 of the mixed lineage kinase family with high sequence identity to Dual Leucine Zipper Kinase (DLK/MAP

218 Three isolates (12%) had 100% sequence identity to each other by 16S rRNA and 99.3 to

219 UBL proteins share little amino acid sequence identity to each other, yet they share similar

220 s SegB is an archaea-specific factor lacking sequence identity to either eukaryotic or bacterial prot

221 ll protein chains in VIPERdb filtered at 40% sequence identity to identify distinct capsid folds, and

222 pts were constructed with a similar level of sequence identity to just 11 SSTs.

223 nated strain IS2.3), with 100% 16S rRNA gene sequence identity to Mycobacterium aurum, which degraded

224 three-finger toxin (3FTx) family, with high sequence identity to neurotoxins and low identity to the

225 a to membrane compartments and (ii) the high sequence identity to the preferentially cytoplasmic AKAP

226 s in crystal structures but lack significant sequence identity to the respective TGR5 sequence, we co

227 ally built from template structures with low sequence identity to the target sequence, using a sequen

228 imeric aconitase repressor AcnR, assigned by sequence identity to the TetR family.

229 rtificially evolved sequences, whose average sequence identity to the wild-type sequences is as low a

230 d, of structures of proteins with detectable sequence identity to them.

231 Their genomes show up to 68% nucleotide sequence identity to Thogoto virus (segment 2; approxima

232 cluding (1) novel strains with <98% 16S rRNA sequence identity to validly described species, (2) clos

233 Because of low sequence identities, understanding the structural basis

234 Given their high degree of sequence identity, we examined whether Hdac1 and Hdac2 w

235 d these two chemokines that only share a 37% sequence identity, we mapped their epitopes on human CXC

236 Despite there being low sequence identity, we observed that Scl2.3 globular doma

237 Protein-coding genes share 93% nucleotide sequence identity, whereas pseudogenes are only 82% iden

238 .1-p21 and is most homologous to CAPN13 (36% sequence identity), which is located 365 kb downstream o

239 protein (PPE15) that showed weak amino acid sequence identities with mammalian perilipin-1 and was u

240 irus (EBV) BBLF1 shares 13 to 15% amino acid sequence identities with the herpes simplex virus 1 UL11

241 GFLOMT1 showed the highest sequence identity with 6-O-methyllaudanosoline 4'OMT and

242 ity among closely related homologues (>/=80% sequence identity with a parent) but APRs are more conse

243 tity among homologues that have at least 50% sequence identity with a parent.

244 The three enzymes showed a 57%-71% sequence identity with a proteinase previously cloned fr

245 MppR shares a low, but significant, level of sequence identity with acetoacetate decarboxylase.

246 nce of the alpha2 nAChR subunit and the high sequence identity with alpha4 (78%) and other neuronal n

247 s substrate specificity and 28.5% amino acid sequence identity with an Aspergillus fumigatus entity.

248 Certhrax shares 31% sequence identity with anthrax lethal factor from Bacill

249 d TPR-repeat protein, but shows only limited sequence identity with any protein of known structure.

250 a Ghanaian bat isolate (GhV-G) exhibits <30% sequence identity with Asiatic NiV-G/HeV-G.

251 an acidic lipid binding protein, shares high sequence identity with beta- and gamma-synuclein.

252 We identified a novel gene based on its sequence identity with ccm2, which we have named ccm2-li

253 ne/threonine protein kinases that exhibit no sequence identity with conventional eukaryotic protein k

254 is 509 amino-acid enzyme, having 67% and 26% sequence identity with CotA from Bacillus subtilis and B

255 evertheless, the maximum pairwise amino acid sequence identity with currently recognized flaviviruses

256 ough this protein only has approximately 20% sequence identity with eukaryotic actin, phylogenetic an

257 They share 19 to 21% sequence identity with firefly luciferases, which produc

258 tein A (CENP-A), shares about 50% amino acid sequence identity with H3.

259 opsis encodes an enolase with 72% amino acid sequence identity with human ENO1.

260 milar transmembrane topology and significant sequence identity with human HASs and likely synthesizes

261 e lysozyme (HEWL) ortholog, which shares 61% sequence identity with human lysozyme.

262 e-dominant chicken RPE65 (cRPE65) shares 90% sequence identity with human RPE65 (hRPE65) but exhibits

263 s, which typically share high structural and sequence identity with IrisFP.

264 son revealed that the Bph32 gene shares 100% sequence identity with its allele in Oryza latifolia.

265 ing only 61.1% (whole genome) and 63.1% (L1) sequence identity with its closest relative in the Papil

266 ith prokaryotic UGM reveals that despite low sequence identity with known prokaryotic UGMs the overal

267 coding for proteins sharing high amino acid sequence identity with members of the Ros/MucR transcrip

268 We show that, despite their low sequence identity with metazoan tetraspanins, plant tetr

269 cid substitutions out of a total of 504 (97% sequence identity with native).

270 GFLOMT2 displayed the highest amino acid sequence identity with norlaudanosoline 6-OMT, showed a

271 ntatively named BoNT/X, which has the lowest sequence identity with other BoNTs and is not recognized

272 a-lactamases, the CTX-M family possesses low sequence identity with other enzymes.

273 Although ALDH1A3 shares high sequence identity with other members of the ALDH1A famil

274 hei ENT1 (PbENT1) shares only 60% amino acid sequence identity with PfENT1, we sought to characterize

275 SIGLEC1 Ig domain shares approximately 22% sequence identity with PILRalpha, an identity that inclu

276 trains 11a and 11a5 share 100% 16S rRNA gene sequence identity with previously sequenced Dhc strains

277 ic characterization of the ISPs is a lack of sequence identity with proteins of known structure or fu

278 enzyme: firstly by mutating RadA to increase sequence identity with RAD51 in the BRC repeat binding s

279 BbdA shows low amino acid sequence identity with reported amidases and is encoded

280 l despite retaining as low as 30% nucleotide sequence identity with rpoA genes from outgroups in the

281 Genome segment 5 of IND1988/02 shows >99% sequence identity with some other BTV isolates from Indi

282 be essential for viability and to have high sequence identity with SPases from other pseudomonads (>

283 COI gene of the Japanese specimen shared 99% sequence identity with the Bemisia 'JpL' genetic group.

284 hogen Pseudomonas aeruginosa shares over 84% sequence identity with the corresponding elongation fact

285 Hxs2) in Cryptococcus that share the highest sequence identity with the glucose sensors Snf3 and Rgt2

286 terminal transactivation (C-TAD) shared high sequence identity with the human HIF-1alpha and HIF-2alp

287 Ig-V)-like fold, despite sharing very little sequence identity with the Ig-V superfamily.

288 Whereas ABCB4 shares high sequence identity with the multidrug transporter, ABCB1,

289 toxin was found to share only 87% amino acid sequence identity with the nearest Stx1 subtype referenc

290 toxin family, sharing only 30-40% amino acid sequence identity with the others.

291 treptomyces scabies Scabin shares nearly 40% sequence identity with the Pierisin family of mono-ADP-r

292 in particular shares virtually no amino acid sequence identity with the residues that have been repor

293 BioY shares only 16% sequence identity with the thiamin-specific S component

294 e c-type cytochrome domain of cN shares high sequence identity with those localized c-terminally in c

295 (PB2, PB1, PA, HA, NA, and NS) sharing >99% sequence identity with those of H7N8 turkey isolates was

296 TPase, VirD4, a protein that shares only 12% sequence identity with VirB4.

297 actored" gene cluster that shares little DNA sequence identity with WT and for which the function of

298 of evolutionary conservation extending from sequence identity within the genome to the underpinnings

299 demonstrated that despite the high level of sequence identity, yapK is distinct from yapJ in its con

300 paramyxoviruses, these domains share little sequence identity yet are similar in length and structur