ライフサイエンスコーパス: sera

1 ed by Western blot with pooled or individual sera.

2 ed by ADCC mediated by HIV-positive (HIV(+)) sera.

3 mbination with other epitopes, using patient sera.

4 g H7N9 and H5N1, have been detected in human sera.

5 ors by 3T3-L1 adipocytes as well as in human sera.

6 ca was 33% (14/43) from the available stored sera.

7 circulating EDA in cord blood than in adult sera.

8 p15 and/or Cp23 antigens between consecutive sera.

9 s was observed between pre- and postpandemic sera.

10 ry enriched by panning on the pool of cancer sera.

11 rocessed foods and the reactivity to patient sera.

12 nspecific background binding in CCD-positive sera.

13 lood group O allogeneic RBC in 22% of tested sera.

14 x antibodies were found in 162 of 1131 (14%) sera.

15 or GI.1 infection, as measured from archived sera.

16 0% and the other proteins with <33.3% of the sera.

17 he secretion of specific antibodies into the sera.

18 sed to evaluate immunoreactivity using human sera.

19 stress accompanied by lowered cholesterol in sera.

20 mal fusion was observed with postvaccination sera.

21 nosa BSI; 56 cases were accompanied by acute sera.

22 om ADCC-mediating antibodies present in HIV+ sera.

23 V4 to neutralization by DENV3 primary immune sera.

24 ells to ADCC mediated by HIV-positive (HIV+) sera.

25 IV-1-infected cells to ADCC mediated by HIV+ sera.

26 Of the remaining 72 double-negative sera, 10 (14%) immunoprecipitated (125)I-alphaDTX itself

27 and in detecting stage II and III LD patient sera (100% and 100% sensitivity).

28 IgE reactivity of 10 CCD-positive sera (14.0-52.5 kUA/L) with the recombinant allergens rP

29 h peach leaf extract revealed in six patient sera a pair of bands of 10 and 16 kDa, and in nine a 16-

30 atography, we obtained from HCV-seronegative sera a purified fraction enriched in inhibitory factors.

31 the broadest reactivity with myeloma patient sera after allogeneic HSCT and that may be significantly

32 The findings suggest that convalescent sera alone is not sufficient for providing 100% protecti

33 Chimpanzee sera also showed robust neutralizing activity against RA

34 GT, but not bmGT, was detected in 71% of sera and 50% of BALF of neutropenic mice; neither was de

35 kidney extracts by immunoblot using patient sera and an anti-alpha-Gal antibody.

36 tibodies have since been isolated from human sera and associated with positive and negative outcomes

37 lyzed by collecting draining lymph nodes and sera and by challenging the animals.

38 ication of favorable donors with potent bnAb sera and by development of improved methods for human an

39 oduct FFA]/[precursor FFA] ratios in fasting sera and clinical data from 481 individuals who particip

40 immunoassay analysis with rabbit polyclonal sera and human IgE indicated only minor differences in p

41 ng unit were used to screen human and rabbit sera and identify epitope hits.

42 ndpoint titers and avidity indices of IgG in sera and IgA in tracheal, lung, and intestinal secretion

43 emained higher with IgHPolyFab in the normal sera and in IVIg, but the reverse was true when the auto

44 P) activities, were present with both immune sera and isolated MAbs, confirming the induction of nonn

45 In addition, both sera and mAbs from the dengue-infected patients enhanced

46 In the current study, both immune sera and monoclonal antibodies from vaccinated humans sh

47 horesis SDS-PAGE-immunoblotting with patient sera and rabbit serum anti-Pru p 3.

48 red HLA (r = 0.40) and highest using diluted sera and SAB with 30% or less denatured HLA (r = 0.86).

49 I and C1q-SAB MFI was lowest using undiluted sera and SAB with greater than 30% denatured HLA (r = 0.

50 posure (cotinine level) in archived maternal sera and schizophrenia in offspring from a national birt

51 was also impaired for survival in guinea pig sera and sheep blood.

52 roduced particles and particles from patient sera and stool samples.

53 tudy used the Danish archived midgestational sera and their nationwide registers to search for antibo

54 easured TG level in fruit juices, beverages, sera and urine samples and reused upto 200 times over a

55 IL-6, TNF-alpha, MCP-1/CCL2 and IFN-gamma in sera, and ameliorated the organ damage of liver and kidn

56 sociated protein-like 2 (CASPR2) in maternal sera, and to relate them to subsequent psychiatric diagn

57 nsor was developed for the identification of sera antibodies (human IgG) from patients with spotted f

58 The rejection-associated miRNAs in sera appear to be ectopically expressed liver and specif

59 ence reaction, however two samples of paired sera are necessary to confirm the diagnosis, since using

60 Human sera are the first choice as controls for diagnostic app

61 hritis patients, C4d-PEDF complexes found in sera arise from the joints, as well as from other tissue

62 Trichinella serology on patient sera as well as polymerase chain reaction (PCR) and larv

63 Distinct miRNA levels profiled from sera at the time of clinical allograft dysfunction can b

64 nant allergens were compared in CCD-positive sera before and after inhibition with a CCD inhibitor (M

65 Of 52 CCD-positive sera (bromelain, 1.01-59.6 kilounits of antigen per lite

66 with pathogenic IgM antibodies from patient sera but with only micromolar affinity.

67 2 protein was detected in 16 of the 40 human sera by ELISA.

68 In this study, we examined human and swine sera by swine or human TTV-specific PCRs, to determine w

69 and microarray technology, respectively, in sera collected at ages 1, 2, 3, 5, 6, 7, 10, 13, and 20

70 Pre- and postpandemic sera (sera collected before and after isolation of the referen

71 We quantified immunological parameters in sera collected before the SM event in cases and their in

72 hypothesis, we measured the ability of human sera collected between 1979 and 2010 to block glycan bin

73 We reviewed PRNT results of sera collected for diagnosis of ZIKAV infection from 1 J

74 agglutination-inhibition (HAI) assays, using sera collected from 382 individuals prior to the 2013-20

75 We cultured human podocytes with sera collected from DKD patients, who displayed elevated

76 rried out untargeted metabolomic analysis of sera collected from female BALB/c mice experimentally in

77 ared ADCC-mediating antibodies (ADCC-Abs) in sera collected from healthy infants, children and adults

78 Sera collected from patients before and during AIT with

79 ducted on 3698 swine sera, including archive sera collected in 2009, as well as samples collected in

80 Sera collected in 2015 showed a high prevalence of IDV a

81 tion of RSV PRNT <1:200 in one-third of cord sera confirms the need to increase levels of RSV neutral

82 rmore, levels of VEGF-D and MCP-1 in patient sera correlated positively with each other.

83 mimHNK-1)45 the inhibitory effect on patient sera could be improved by a factor of up to 230,000 per

84 Twenty of the 53 paired sera demonstrated a >/=4-fold increase in antibody titer

85 e was changed because human, but not ferret, sera distinguish A(H1N1)pdm09 viruses isolated after 201

86 In analyses of 500 sera, ELISA using rLb6H detected all 219 ATL samples (se

87 Post-AIT sera exerted IgE-blocking activity.

88 Sera exhibiting elevated binding without reduction after

89 Using a set of pooled human sera exposed to OPNAs as quality control (QC) materials,

90 Stools were tested for rotavirus and sera for antirotavirus immunoglobulins by enzyme immunoa

91 dized reagents to monitor complex polyclonal sera for neutralization activity and to characterize the

92 pteronyssinus or D. farinae were assessed in sera from 1302 house dust mite (HDM)-allergic patients l

93 d metabolomic assay was performed in fasting sera from 136 CHB patients, 104 HBV-associated cirrhosis

94 Pretransplant and posttransplant sera from 162 lung recipients transplanted at 3 centers

95 -C6 antibodies were detected in pretreatment sera from 17 of 29 (59%) subjects, whereas only 5 of 29

96 Sera from 193 adult patients with moderate-to-severe AD

97 Sera from 20 subjects with moderate to severe AD, 10 sub

98 f IDV antibody titers (11.7%), while archive sera from 2009 showed statistically significant lower po

99 r binding of annexin A2 to sialostatin L2 in sera from 21 out of 23 infected patients than in sera fr

100 Furthermore, sera from 21 participants at three different time points

101 Sera from 25 highly sensitized patients were tested usin

102 broadly neutralizing antibodies (bnAbs) and sera from 30 subjects with chronic clade C infections.

103 We tested sera from 31,255 residents of Olmsted County, Minnesota

104 Sera from 35 children with proven CMA (median age at inc

105 g a custom-designed proteome microarray with sera from 35 healthy US adults revealed a continuous dis

106 processing were analyzed by immunoblot with sera from 52 peanut-allergic individuals displaying diff

107 Metabolomics-based analyses of sera from 7 patients with and 9 without T1R were conduct

108 Sera from 820 patients were screened on GGTA1/CMAH/B4Gal

109 Pentraxin-3 (PTX3) analyses of sera from 87 leprosy patients with or without reactions

110 ssessed by Luminex in acute and convalescent sera from 91 EM patients, in serum and synovial fluid fr

111 s compared with that of real-time PCR, using sera from a cohort of acutely infected individuals, in a

112 We screened sera from a cohort of Gambian children followed for six-

113 All tests were performed on sera from a recently available, well-defined archive of

114 t H7N9 virus-infected cells were detected in sera from adults and children but not infants.

115 Sera from all three mouse strains enhanced HAdV-5 transd

116 rChiA was verified by immunoblot assays with sera from allergic subjects.

117 her levels of EGFL7 protein are found in the sera from AML patients than in sera from healthy control

118 actors including 3D nature of embryoid body, sera from animals, and the feeder cells isolated from mo

119 On a 7,455 peptide Pf proteome array, immune sera from at least 5 out of 9 group III vaccinees recogn

120 We then assessed rLb6H against sera from ATL patients infected with different species o

121 among these species and cultivars, mainly in sera from atopic patients that react to lupin rather tha

122 Sera from children and adolescents with newly diagnosed

123 IgE-immunoblotting was also conducted using sera from children with wheat allergy.

124 other but poorly with those determined using sera from children.

125 st 16 broadly neutralizing antibodies and 30 sera from chronic clade C infections.

126 Using a combination of animal models and sera from clinically well-characterized patients, we hav

127 ic activity of the formulas were tested with sera from CM-allergic patients (n = 26) in RAST-based as

128 from 21 out of 23 infected patients than in sera from control individuals was also demonstrated.

129 sed concentrations of soluble B7 compared to sera from controls.

130 effect of treatment on complement activity, sera from dosed subjects were analyzed in a CP activatio

131 and aggregated ovalbumin were measured with sera from egg-allergic children and from mice sensitized

132 d the levels of IL-6 and related proteins in sera from emphysematous mice and patients were also asse

133 od group antigen (HBGA) blocking assay using sera from GII.4 and the GII.17 variant-infected patients

134 form was constructed and immunoscreened with sera from healthy (n = 49), lung cancer (LC) (n = 31) an

135 found in the sera from AML patients than in sera from healthy controls.

136 otropic reagent Urea and probing with immune sera from healthy individuals (n = 109) increased ELISA

137 to sensitize HIV-1-infected cells to ADCC by sera from HIV-1-infected individuals.IMPORTANCE HIV-1 ev

138 eHAV produced in cell culture or present in sera from humans with acute hepatitis A.

139 ely evades polyclonal anti-AAV1 neutralizing sera from immunized mice and rhesus macaques.

140 ry products of O. viverrini and reacted with sera from infected hamsters and humans.

141 RNAs isolated from extracellular vesicles in sera from infected individuals may provide a new tool fo

142 of vaccine sera will be relative to that of sera from infected individuals.

143 e retaining its resistance to antibodies and sera from infected macaques.

144 This array was interrogated with sera from infected mice, rhesus monkeys, and humans and

145 Pre- and postvaccination sera from kidney transplant recipients (n = 60) immunize

146 ed, because AP activity is still observed in sera from MASP-1/3-deficient Malpuech-Michels-Mingarelli

147 stimulating cellular proliferation when the sera from mice are injected sc with individual liposome-

148 Sera from mice immunized with a single GII.17 VLP identi

149 Sera from mice with acetaminophen-induced liver injury c

150 tained high levels of soluble B7 compared to sera from mice without liver injury.

151 city (ADCC) have been shown to be present in sera from most HIV-1-infected individuals.

152 was established by culturing DCs with pooled sera from multiple non-small cell lung cancer (NSCLC) pa

153 2-tier test) were equivalent in identifying sera from negative-control subjects (99% and 100% specif

154 ed viruses, we tested acute and convalescent sera from nine Thai patients with PCR-confirmed DENV inf

155 We found that treatment of podocytes with sera from normoalbuminuric type 1 diabetes patients with

156 Furthermore, using human immune sera from pandemic A/California/04/2009 immune subjects

157 y controls, cultured in the presence of both sera from patients and mtDNA, reproduced a refractory st

158 tilized to detect HM14c10-like antibodies in sera from patients who recovered from DENV-1, infection

159 Principal component analysis of data on sera from patients with AD revealed the presence of 4 po

160 more, elevated IL-16 levels are found in the sera from patients with AIH, hepatitis B virus, hepatiti

161 Plasma exchange reduces levels of B7 in sera from patients with ALF and might be used to restore

162 sion of CTLA4 after 24-48 hours culture with sera from patients with ALF; these sera were found to ha

163 pathway activation and hemolysis induced by sera from patients with atypical hemolytic uremic syndro

164 In addition, anti-SSA/Ro-positive sera from patients with connective tissue diseases showe

165 more anti-basement membrane antibodies than sera from patients with CRSwNP and control subjects (P <

166 sing quantitative proteomics of pretreatment sera from patients with grass pollen allergy reveals tha

167 Finally, assessment of AnxA1 levels in sera from patients with LCL or ML revealed that ML patie

168 tide was found using anti-SSA/Ro Ab-positive sera from patients with QTc prolongation.

169 at detecting Borrelia-specific antibodies in sera from patients with stage I LD.

170 were the most abundant antigens detected in sera from patients.

171 Sera from RV-positive children and adults hospitalized w

172 d aqueous pollen protein extract (APE) using sera from short ragweed pollen-sensitized patients.

173 uman CD4-Ig, SIV neutralizing antibodies, or sera from SIV-infected macaques.

174 Antigenic maps determined using sera from subjects 18-64 and >/=65 years of age correlat

175 Sera from subjects who received 2 doses of MF59-adjuvant

176 Sera from suspected ZIKV-infected patients were analyzed

177 Also, 30 ZIKV(+) sera from symptomatic pregnant patients showed elevated

178 Sera from term- and preterm-born infants were also colle

179 d on a well-characterized panel of 279 human sera from the CDC, comparing ELISAs using these two reco

180 nked immunosorbent assay, we analyzed serial sera from the START study to decipher the various anti-A

181 Sera from two different generations of Uzbek (n=58) and,

182 Sera from two individuals had discordant results on the

183 A small 12-Env panel was chosen to screen sera from vaccine trials or natural-infection studies fo

184 found to improve liver glycogen storage and sera glucose level in mice expressing human AATZ mice.

185 peptides, we found that 9 of 17 (53%) paired sera had a >/=4-fold increase in antibody titer to clust

186 In addition, animals whose sera had high capture but weak anti-infectivity activity

187 f enhanced ZIKV replication by dengue-immune sera have raised concerns about the role of previous DEN

188 r to characterize cross-reactive breadth for sera identified as having potent neutralization activity

189 evels of interleukin-15 present in patients' sera, immature NK cells (CD62L(+)NKG2A(+)KIR(-)) became

190 r was able to escape Nab activity from mouse sera immunized with parental serotypes.

191 lidated by enzyme-linked immunoassays of the sera in a certified laboratory.

192 tion of histamine in synovial fluid (SF) and sera in patients with RA was measured using ELISA.

193 rological tests were conducted on 3698 swine sera, including archive sera collected in 2009, as well

194 Chronically HCV-infected patient sera inhibited C3 convertase activity, further implicati

195 cing, the large number of cancer and control sera is required to identify cancer-specific peptides wi

196 carcinoma, whereas decline of AAT levels in sera is responsible for pulmonary emphysema.

197 human sera, IVIg, and allograft recipients' sera, it was observed that the number of HLA-Abs was not

198 gHPolyFab and FcMonoIgG against normal human sera, IVIg, and allograft recipients' sera, it was obser

199 tients with Graves' disease, but not control sera, led to secretion of TG with an increased intrinsic

200 For undiluted sera, Luminex mean fluorescence intensity (MFI) values f

201 myosin showed IgE reactivity with 60% of the sera, lysosomal aspartic protease, and "AAEL006070-PA" (

202 e immunoreactivity of onchocerciasis patient sera (n = 152) from the Americas, West Africa, Central A

203 Sera (n=1131) from several clinically defined cohorts we

204 Furthermore, such sera neutralized influenza virus, whereas this effect wa

205 Sera obtained from 29 healthy adults before and after pr

206 label-free mass spectrometry in pretreatment sera obtained from clinical responders and nonresponders

207 Sera of 1062 patients with CSU and 482 healthy control s

208 We examined sera of 148 children participating in the Multicentre Al

209 EBV gp350-specific IgG was detected in the sera of 17 (71%) of 24 individuals at the time of AIM an

210 and free fatty acid profiles was applied to sera of 381 individuals in 2 independent studies.

211 We investigated the clinical data and sera of 722 participants in the German Multicenter Aller

212 neutralizing antibodies were detected in the sera of all immunocompetent animals.

213 iate an allergy, such as allergic asthma, in sera of allergic subjects.

214 preferentially recognized by antibodies from sera of an MS patient subpopulation.

215 t of potentiometric determination of urea in sera of apparently healthy and persons suffering from ki

216 y quantifying anti-Neu5Gc antibody levels in sera of children enrolled in 2 farm studies: the Prevent

217 bserved from HCV-infected hepatocytes and in sera of chronic HCV patients with fibrosis compared to h

218 tion and concanavalin A binding assays using sera of cypress pollen-sensitized patients.

219 Sera of EDA-deficient patients contained either backgrou

220 ignificantly lower levels (P < 0.003) in the sera of HCC patients compared with healthy volunteers.

221 the formation of LVPs that circulate in the sera of HCV patients and are also produced in an in vitr

222 ification of protein and miRNA biomarkers in sera of ill children reflecting brain damage and T. gond

223 -BPA and BPA-glucuronide were quantitated in sera of individual PND 3 pups collected 1 hr postexposur

224 beta by Rickettsia-infected BMDCs and in the sera of infected mice were significantly reduced in MyD8

225 The molecule is also reactive with IgE from sera of maize-allergic subjects.

226 reased level of proinflammatory cytokines in sera of mice infected with the virus lacking the m20.1 a

227 Sera of mothers with a CMA infant had increased binding

228 s in vivo, was significantly elevated in the sera of newly diagnosed AML patients and is a strong ind

229 We found sera of patients with ALF and from mice with liver injur

230 brain extracts using autoantibodies from the sera of patients with diabetes before SDS-PAGE.

231 ulators of the serum protein patterns in the sera of patients with diffuse cutaneous systemic scleros

232 he head and neck SCCs, and EVs isolated from sera of patients with SCC were enriched in Dsg2 C-termin

233 ls of soluble MICA proteins were detected in sera of pSS patients compared to healthy controls.

234 nd levels of the complexes did not differ in sera of RA patients and healthy controls.

235 = 0.002) were significantly elevated in the sera of systemic sclerosis patients.

236 The polyclonal sera of the three donors also reflect this preference.

237 tained and even enhanced its presence in the sera, over ten years post infection; the prevalence of o

238 Of 158 sera/plasma from RT-PCR-confirmed ZIKV infections, 145 (

239 ed susceptibility to neutralization by human sera pooled from approximately 60 to 80 North American d

240 er cancer associations differed by hepatitis sera-positivity in nested analyses for a subset of cases

241 The observation that prepandemic sera possess robust blocking capacity for viruses identi

242 We found that prepandemic sera possess robust virus-blocking capacity against viru

243 We found that 16% of the sera proteins analyzed by SOMAscan aptamer technology, f

244 Unique sera proteomic signatures may distinguish between inflam

245 ody competition studies revealed that immune sera raised to high-molecular-weight Delta123 was poly s

246 By contrast, the immune sera raised to monomeric Delta123 predominantly blocked

247 epitope specificity between BM and maternal sera ranging from only 13% of sample pairs sharing at le

248 33% of the sera recognized a doubled band of about 14.5 kDa and thi

249 and 217 MGBs were identified from TD and ASD sera respectively, of which 74 proteins were specially i

250 Comparison of the C57 and mdx sera revealed 83 proteins with statistically significant

251 Some patient sera revealed IgE-binding proteins matching LTP and/or p

252 PFAAs were analyzed in 50 maternal sera samples collected in 2007-2008 from participants in

253 We studied sera samples from 3 groups of subjects aged >/=65 years

254 Pre- and postpandemic sera (sera collected before and after isolation of the r

255 We observed that some CCD-positive sera show nonspecific IgE binding even with CCD-free rec

256 Furthermore, these immune sera showed antiviral activities against a panel of gene

257 Moreover, paired sera showed that blocking titers of >/=160 were maintain

258 ence of heterologous and autologous post-AIT sera significantly reduced the allergic airway inflammat

259 tope-specific IgA was detectable in infants' sera starting at less than 3 months of age.

260 ways were simultaneously repressed by cancer sera, suggesting that the attenuated NF-kappaB and STAT3

261 uppression withdrawal were also evaluated in sera taken at predetermined intervals during immunosuppr

262 Fc established allergen-specific artificial sera that showed comparable results for more than 20 all

263 In contrast to pre-AIT sera, the presence of heterologous and autologous post-A

264 g them with human and/or ferret convalescent sera to human H1N1 and H3N2 viruses.

265 While liver, but not sera, total bile acids (TBAs) were increased 75% by this

266 re was a good correlation (r = 0.99) between sera urea values obtained by reference method (Enzymic c

267 nd food allergen components were analyzed in sera using allergen microarray and compared between 5 Fr

268 frequency of some LTP isoform by our patient sera was 42%.

269 The IgE-blocking activity of post-AIT sera was assessed in vitro.

270 s reactive in 6 of 8 (75%) patients for whom sera was available.

271 Furthermore, the autoreactive capacity of CU sera was evaluated and urticaria-related symptoms were a

272 Recognition of NF54 PEs by immune sera was observed, suggesting P. falciparum erythrocyte

273 tion of the FcgammaRI reporter by survivors' sera was substantially high one year after acute infecti

274 e site-specific antibodies in vaccine immune sera, we demonstrated that vaccination elicited function

275 The sera were analyzed to characterize all IgG subclasses an

276 Pre- and postinfection sera were assayed by enzyme-linked immunosorbent assay w

277 Sera were assessed for autoantibodies using ELISA assays

278 ins, VRC01 concentrations from participants' sera were found to avidly capture HIV virions and to med

279 ture with sera from patients with ALF; these sera were found to have increased concentrations of solu

280 Human sera were incubated with RBC isolated from various genet

281 In total, 268 sera were investigated for 50% blocking titer (BT50) val

282 Pretreatment and posttreatment sera were obtained from 48 women with metastatic HER2(+)

283 Peripheral blood mononuclear cells and sera were obtained from individuals with grass pollen al

284 In some experiments, sera were pre-incubated with alpha-gal or protein G to d

285 ere tested for ZIKV-specific antibodies, and sera were screened for other congenital infections.

286 poallergenic Cyp c 1 mutant mouse and rabbit sera were tested for their ability to inhibit IgE recogn

287 The 17 paired sera were tested in bactericidal assays against selected

288 Sera were tested undiluted, at 1:20 dilution to detect h

289 e neutralization-response profile of vaccine sera will be relative to that of sera from infected indi

290 Bacterial inoculum was measured in patient sera with elevated (n = 8) or low (n = 8) IL-10 using a

291 enic maps derived from human postvaccination sera with H1 influenza preexposure also correlated poorl

292 serum Abeta42, and to be able to identify AD sera with high sensitivity.

293 Our data demonstrate that post-AIT sera with IgE-blocking activity ameliorate allergic airw

294 The sera with LGI1 and CASPR2 antibodies immunoprecipitated

295 so correlated poorly with those derived from sera with neither H1 nor type B influenza preexposure, a

296 wed good correlation with those derived from sera with neither H1 nor type B influenza preexposure.

297 enic maps derived from human postvaccination sera with only type B influenza preexposure consistently

298 ype H1N1 viruses, COBRA HA antigens elicited sera with the broadest HAI reactivity against multiple a

299 of an immunoglobuline preparation and three sera with unfolded CMV antigens enhanced clearly the neu

300 vitro neutralization by MV polyclonal immune sera without altering its thermostability.