ライフサイエンスコーパス: serine residue

1 s partially rescued by removing the adjacent serine residue.

2 e and perturbs the position of the catalytic serine residue.

3 ch is controlled by an N-terminal regulatory serine residue.

4 s a G-to-S change at the predicted catalytic serine residue.

5 ced the highly conserved cysteine 107 with a serine residue.

6 key residue for binding is a phosphorylated serine residue.

7 from phosphorylation of the newly introduced serine residue.

8 tanoyl side group, which occurs on its third serine residue.

9 n responded to modification of even a single serine residue.

10 ted following phosphorylation at a conserved serine residue.

11 tly phosphorylates SRF on a highly conserved serine residue.

12 mapping and mutating the key O-GlcNAcylated serine residues.

13 ons, including modification of glutamine and serine residues.

14 -acetylglucosamine (O-GlcNAc) also occurs on serine residues.

15 inase 1 (Clk1) phosphorylates SPF45 on eight serine residues.

16 ymes through nonenzymatic acetylation of key serine residues.

17 rane binding and phosphorylation at specific serine residues.

18 step formal cycloaddition between two distal serine residues.

19 elium SCAR is basally phosphorylated at four serine residues.

20 effects based on phosphorylation at specific serine residues.

21 hosphorylation switch of adjacent lysine and serine residues.

22 ic peptide containing N-terminal alanine and serine residues.

23 phosphoprotein exclusively phosphorylated at serine residues.

24 e composed almost entirely of tryptophan and serine residues.

25 rylation site mutations at each of the three serine residues.

26 mediates Smad1 phosphorylation at C-terminal serine residues.

27 function of each of these two phosphorylated serine residues.

28 oteins, and (iii) phosphorylation of various serine residues.

29 ciated with dephosphorylation of the Ntcp on serine residues.

30 of three hydrophobic amino acids flanked by serine residues.

31 are within casein kinase 2 (CK2) sites, and serine residue 114, which is within a protein kinase A (

32 Here we identify serine residue 1166 (Ser1166) in the carboxy-terminal ta

33 ion of the Na-K-2Cl cotransporter (NKCC2) at serine residue 126 (pS126 NKCC2) and of the Na-Cl cotran

34 enic-transforming activity depends on intact serine residues 127 and 381, two sites that could be pho

35 lated on three serine residues, specifically serine residues 16 and 18, which are within casein kinas

36 r sites of ICP27 that are phosphorylated are serine residues 16 and 18, within a CK2 site adjacent to

37 Here we report that phosphorylation of serine residues 17 and 24 flanking the Bnip3 LIR promote

38 that constitutively active IKKbeta in which serine residues 177/181 were mutated into negatively cha

39 We discovered that dual serine (traditional serine residues 177/181) and tyrosine (188/199) phosphor

40 PKC-dependent NMDAR insertion, and identify serine residue-187 as the molecular target of PKC phosph

41 ndividually contained one of six cysteine-to-serine (residues 193, 197, 209, 211, 214, and 218) subst

42 Mass spectrometry shows that serine residues 2 and 5 of the pol II C-terminal domain

43 CK2 phosphorylated 14-3-3gamma at serine residue 235 and Dok-7 at several serine residues

44 o 2.8-fold increased phosphorylation of Cx43 serine residues 255, 262, 279/282, and 368, and appeared

45 ion with MEF2s in nuclear speckles requiring serine residues 259 and 498, whose phosphorylations cont

46 These results clearly indicated that serine residues 271, 273, and 275 influence the HIV-1 co

47 RK1A can specifically phosphorylate LIN52 on serine residue 28, and that this phosphorylation is requ

48 somal neural-derived IRS-1 phosphorylated at serine residue 307 (corresponding to serine residue 312

49 ated at serine residue 307 (corresponding to serine residue 312 in humans) negatively correlated with

50 sulin receptor substrate-1 phosphorylated at serine residue 312 in neurons and oligodendrocytes in th

51 ceptor substrate 1 (IRS-1) phosphorylated at serine residue 312 was more apparent in inclusion bearin

52 cal WW domain-mediated interaction involving serine residues 324 and 325 within the carboxy-terminal

53 MMEJ, is dependent on the phosphorylation of serine residue 327 and recruitment of BRCA1.

54 In humans, serine residues 367, 1893, and 1981 have been shown to b

55 physiological role of AID phosphorylation at serine residue 38 (S38), and even the requirement for th

56 AID that is phosphorylated on serine residue 38 interacts with replication protein A (

57 MST4 phosphorylates ATG4B at serine residue 383, which stimulates ATG4B activity and

58 ABAARs is potentiated via phosphorylation of serine residues 408 and 409 (S408/9) in the beta3 subuni

59 tion, the beta3 subunit is phosphorylated on serine residues 408/409 by PKC activity, whereas the del

60 Furthermore, phosphorylation of TDP-43 at serine residues 409/410 drives mutant TDP-43 toxicity.

61 site-directed mutagenesis, which identified serine residues 421 and 423 as critical for its nuclear

62 GSK3beta was found to interact with ST2L on serine residue 446 in response to IL-33 treatment.

63 phate 5-kinase type-l gamma (PIP5Klgamma) at serine residue 448.

64 that O-GlcNAc transferase (OGT) modified CTD serine residues 5 and 7.

65 y catalyzing the dephosphorylation of PDE4D3 serine residue 54.

66 tivate SP-1 through dephosphorylation at its serine residue 59.

67 Serine residues 6 and/or 533, potential kinase target si

68 d decreased levels of DRP1 phosphorylated at serine residue 616 (P-DRP1(S616)), a post-translational

69 )-ATPase modulating protein phospholemman at serine residue 63 (S63 PLM).

70 y increased phosphorylation of K8 and K18 on serine residues 73 and 33, respectively.

71 hat PIM1 phosphorylates ASK1 specifically on serine residue 83 (Ser83) both in vitro and in vivo and

72 on cascade that modulates phosphorylation of serine residue 863 (S863) in the GluA1 AMPAR subunit and

73 Allodynia suppression was a consequence of serine residue 896/897 phosphorylation of NMDA receptor

74 els purified from brain is phosphorylated on serine residues 9 and 31, and that cyclin-dependent kina

75 intracellular inhibitor of PP2A (I2PP2A) on serine residues 9 and 93, resulting in enhanced binding

76 We conclude that serine residue 96 of human KCC3 is a third site that has

77 rylation of the pro-NRG1 cytoplasmic tail on serine residues adjacent to the membrane-spanning segmen

78 er, our data suggest that phosphorylation of serine residues adjacent to the PIAS1 SUMO-interacting m

79 O-palmitoylation of a threonine or serine residue, along with a characteristic and highly c

80 ht chain last amino acid, which was either a serine residue, an alanine residue or deleted.

81 tly phosphorylated mTOR and RAPTOR on unique serine residues, an effect that was independent of insul

82 ate that Scute is phosphorylated by Sgg on a serine residue and that mutation of this residue results

83 diversity, consisting mostly of tyrosine and serine residues and a small but significant contribution

84 ion, we induced a mutation in the C-terminal serine residues and examined their effects on the intera

85 minal domain of DGLalpha, phosphorylated two serine residues and inhibited DGLalpha activity.

86 (AICAR) resulted in STIM1 phosphorylation on serine residues and prevented protease-activated recepto

87 structural changes due to phosphorylation of serine residues and shown a correlation between the CTD

88 backbone-backbone hydrogen bonds, a linchpin serine residue, and hydrophobic side-chain packing.

89 erichia coli was phosphorylated by CKII on a serine residue, and its phosphorylation was dependent on

90 y, induced IRS-1 phosphorylation at multiple serine residues, and inhibited physiological IRS-1pTyr i

91 These serine residues are critical for mediating agonist-promo

92 The modified serine residues are located in the phospho-tyrosine bind

93 A serine residue at P3 was required for the stable binding

94 On the other hand, a serine residue at position 105, which is a known target

95 signature depends on phosphorylation of the serine residue at position 273 of PPARgamma, in striking

96 smic tail of rat ADAM17 contains a conserved serine residue at position 811, which resides in a canon

97 AOX1A carrying a serine residue at position CysI was activated by succina

98 ed that the phosphate moiety attached to the serine residue at position P5 of pMART-1 is available fo

99 f-function" mutation [a leucine mutated to a serine residue at the 9' position (Leu9'Ser)] in VTA GAB

100 or tryptophan residue in Env with a natural serine residue at this position (S375H/W) increased the

101 o Uniprot entry P50286 (WoA-S121) that has a serine residue at this position.

102 ur findings show enhanced phosphorylation of serine residues at amino acid positions 15 and 46 in the

103 quent mutagenesis analysis demonstrated that serine residues at amino acids 225 and 232 in NS5A (geno

104 ion in cells leads to phosphorylation of two serine residues at analogous sites on both SH2 domains o

105 o restrict MLV/GaLV Env, but mutation of the serine residues at positions 52 and 56 completely allevi

106 pha-helices have an L-shape, with proline or serine residues at the kinks, which functions as a lever

107 Mutating these serine residues attenuates the ability of Smo to transdu

108 sphorylate TC21 and R-Ras on this C-terminal serine residue both in vitro and in vivo.

109 a at serine residue 235 and Dok-7 at several serine residues but does not phosphorylate Rapsyn or Rac

110 Finally, only the addition of 10 serine residues (but not 2 or 4) between the extracellul

111 defined, conserved N-terminal threonine and serine residues, but the kinase pathways that mediate th

112 Moreover, replacement of the cytosolic serine residues by other ubiquitinatable residues (i.e.

113 c intermediate as well as phosphorylation of serine residues by protein kinase D (PKD).

114 vation, we mutated cysteine 203 of CypD to a serine residue (C203S) and determined its effect on mPTP

115 n article, we show that five, and only five, serine residues can be phosphorylated both in vitro and

116 sidue plays a role in activating an adjacent serine residue carrying out nucleophilic attack, opening

117 y ERK-mediated phosphorylation of ERG at one serine residue causes a conformational change that allow

118 as required, since mutation of the catalytic serine residue completely abolished the stimulatory acti

119 osophospecific antibody, and substitution of serine residues demonstrate phosphorylation of candidate

120 dehydratases such as aconitase, which use a serine residue deprotonated by an oxyanion hole.

121 the observation that mutation of Cys475 to a serine residue eliminates the formation of the protein a

122 quitination, whereas placement of additional serine residues enhanced it.

123 cytosolic S4-S5 linker of both proteins by a serine residue forces the channels into an open conforma

124 -R353A, but not FXII lacking the active site serine residue (FXII-S544A), shortened the clotting time

125 Conversely, the replacement of His 375 by a serine residue (H375S) within HIV-1 CRF01_AE decreased t

126 In contrast, this mutant at serine residues had no demonstrable impact on apelin-13-

127 Although mutating these serine residues had no effect on binding between ORF59 a

128 ough its serine-rich domain in which most of serine residues have the propensity to be phosphorylated

129 Two serine residues, i.e. serine 362 and serine 604, were id

130 n I; group B, comprising mutations affecting serine residues important for hyperphosphorylation and a

131 ime, the occurrence of O-xylosylation at the serine residue in (G4S)n>2 linkers.

132 sporter EAAT2, and we identified a conserved serine residue in Flot1 that is essential for transporte

133 The cysteine residue is followed by a serine residue in IgG1lambda.

134 In addition, a modification to an adjacent serine residue in Rab1 was discovered, which was indepen

135 Mutation of an additional serine residue in the active site causes the enzyme to b

136 (APC/C); while phosphorylation of a specific serine residue in the APC/C coactivator Cdc20 prevents d

137 ntered on two hydrogen bonds with a specific serine residue in the bound peptide.

138 Here, we show that a conserved serine residue in the Golgi GDP-fucose transporter (GFR)

139 Phosphorylation at a conserved serine residue in the KXGS motif in PSD-95 regulates spi

140 d the consequences of changing the conserved serine residue in the P-loop to asparagine, within a chi

141 mline mutation (S631G) at a highly conserved serine residue in the uncharacterized gene VSIG10L that

142 s, BimEL was rapidly phosphorylated on three serine residues in a conserved degron, facilitating bind

143 he enzyme is regulated by phosphorylation of serine residues in a regulatory domain and by binding of

144 s inhibited by phosphorylation of up to four serine residues in a repeating sequence in the C-termina

145 s regulated by reversible phosphorylation of serine residues in an N-terminal regulatory domain and c

146 ly at Ser12, indicating that the pore-facing serine residues in BM2 mediate proton relay to the proto

147 t stress-induced phosphorylation of specific serine residues in domain 3 of PACT increases its affini

148 equires phosphorylation at three clusters of Serine residues in Drosophila Hedgehog (Hh) signaling.

149 Mutation of the two C-terminal serine residues in MKP-1 and MKP-2 to alanine decreased

150 entially phosphorylated at three clusters of serine residues in response to levels of Hh activity.

151 We identified the serine residues in Smo that can be phosphorylated by CK2

152 and E2 enzymes, SidE effectors ubiquitylate serine residues in substrates via an ADP-ribosylated ubi

153 vered a new form of ADPr that is attached to serine residues in target proteins (Ser-ADPr) and showed

154 ediated interaction involving phosphorylated serine residues in the absence of any proline residues a

155 sphorylation of PKD1 at two highly conserved serine residues in the activation loop; this modificatio

156 1/2) interact directly with CIITA, targeting serine residues in the amino terminus of the protein, in

157 trometry, we first identified phosphorylated serine residues in the C terminus of APJ.

158 dy revealed extensive phosphorylation of two serine residues in the C terminus of both MKP-1 and MKP-

159 MPK-mediated inhibition of TREK involves key serine residues in the C-terminus that are also known to

160 s spectrometry analysis, we identified three serine residues in the CCE domain of CRY2 (S588, S599, a

161 we report that substitution of two conserved serine residues in the cytosolic tail of TCRalpha to ala

162 ificantly enhanced by phosphorylation of key serine residues in the IRF6 C-terminus.

163 ed a mutational analysis of highly conserved serine residues in the linker region between domains I a

164 Many prior papers have pinpointed several serine residues in the low complexity sequence I region

165 fy HDAC1 and the phosphorylation of specific serine residues in the molecule as potential targets for

166 -kinase-C-dependent phosphorylation of three serine residues in the receptor carboxy terminus.

167 thway responsible for the phosphorylation of serine residues in the Ser-x-Glu/pSer motifs in several

168 However, the role of these serine residues in tolerance and dependence for cannabin

169 s can form hydrogen bonds with two conserved serine residues in transmembrane helix 5 (Ser(5.42) and

170 Serine residues in UbL are phosphorylated and influence

171 hway, which phosphorylates Runx2 on multiple serine residues including S301 and S319 (equivalent to S

172 phosphorylation of IRS-1 by S6K1 at multiple serine residues including Ser-270, Ser-307, Ser-636, and

173 vates PDC by phosphorylating PDH at specific serine residues, including Ser-293, whereas dephosphoryl

174 t study of phosphorylated and phosphomimetic serine residues indicating lowered single motor stalling

175 f Dazl by MK2 on an evolutionarily conserved serine residue inhibits its interaction with poly(A)-bin

176 LGST motif from bacteria to humans, only the serine residue is absolutely required for Psd1p autocata

177 reased enzymatic activity, suggesting that a serine residue is critical at that location.

178 osphorylation of kinesin motor domain at the serine residue is implicated in Huntington's disease, wi

179 the nitrogen atom of an internal cysteine or serine residue is usually cleaved by the side chain -SH

180 n of the viral nonstructural protein NS5A at serine residues is important for the efficient assembly

181 t phosphorylation of Rex-2, predominantly on serine residues, is correlated with an altered conformat

182 ing PKCbeta phosphorylation of TFEB on three serine residues located in its last 15 amino acids.

183 d ERK4 are activated by phosphorylation of a serine residue lying within the activation loop signatur

184 Cleavage at a serine residue near the C terminus was a major reaction

185 osphorylation at an evolutionarily conserved serine residue near the carboxyl terminus (Ser-883 in Xe

186 ndergoing inhibition by phosphorylation of a serine residue near the N terminus.

187 pro-apoptotic Bid protein by phosphorylating serine residues near its caspase-8 cleavage site.

188 kt, the enzyme multi-phosphorylated a single serine residue of a diserine DCF substrate in a time-dep

189 established that transesterification of the serine residue of desmethylsalinamide E with acylated gl

190 tide synthetase machinery, to the C-terminal serine residue of microcin E492 (MccE492), an 84 aa ribo

191 hondroitin sulfate (CS) chain, O-linked to a serine residue of the core protein.

192 theine (4-PP) from coenzyme A to a conserved serine residue of their protein substrates.

193 Several serine residues of IRBIT are thought to be important for

194 DDK phosphorylates two serine residues of Mcm2 near the N terminus of the prote

195 We recently specified three serine residues of NIPA and demonstrated a sequential ph

196 b1(SSAA/SSAA)' mice, in which the IKK-target serine residues of p105 were substituted with alanine.

197 subsequent en bloc transfer of the glycan to serine residues of select periplasmic proteins.

198 rthermore, we show that SRPK1 phosphorylates serine residues of SR/RS dipeptides in the hinge region

199 Specific phosphorylation of tyrosine and serine residues of STAT1 was observed in polyI:C-treated

200 effects of phosphorylation of the individual serine residues of stathmin on microtubule dynamic insta

201 ir is capable of conjugating Ub on lysine or serine residues of substrates.

202 ets RNA polymerase II but also the conserved serine residues of the polylinker region in Smad3, sugge

203 the N-terminal structure suggested that the serine residue (of CSQCH) would be anchored where the fi

204 The effect of the serine residue on disulfide bond susceptibility was comp

205 A serine residue on the DIV S2 helix was found to be suffi

206 res phosphorylation of Ser(1107), a critical serine residue on the II-III loop of the channel pore pr

207 Effect of the serine residue on the susceptibility of disulfide bonds

208 he ordered and sequential phosphorylation of serine residues on Chk1 induced by DNA damage.

209 o blocking phosphorylation of at least three serine residues on IRF3.

210 Threonine and serine residues on Notch1 are functionalized with O-fuco

211 s studies have shown that phosphorylation of serine residues on synaptic proteins is a major regulato

212 by GCK-3 kinase-mediated phosphorylation of serine residues on the cytoplasmic C-terminus linker con

213 l six cysteines were individually altered to serine residues, only C145S and C195S derivatives lost t

214 th this prediction, phosphorylation at these serine residues or mutation to aspartate inhibits bindin

215 Furthermore, the introduced serine residue participates in recognition of hydroxypro

216 )KVTF(901), and can dephosphorylate multiple serine residues phosphorylated by checkpoint kinases.

217 press mutant versions of hLigI in which four serine residues phosphorylated in vivo were replaced wit

218 pathway in human cells; additionally, as the serine residue promoting thermal lability is conserved a

219 erential phosphorylation of SPL tyrosine and serine residues provides a key to understanding both.

220 ing with the dockerin's critically conserved serine residues reduced the observed rupture forces.

221 combination of approaches, we identified the serine residue regulating SHIP1 activity.

222 Replacement of the Asp f3 cysteines with serine residues retained its dimeric structure, but dimi

223 We show that Noxa is phosphorylated on a serine residue (S(13)) in the presence of glucose.

224 , we found that PKG can phosphorylate Sp1 on serine residue(s) and this resulted in transcriptional a

225 in activation, we demonstrated a key role of serine residue S1163 of the alphaE chain intracellular d

226 The phosphorylation of two serine residues (S151 and S153) at the C terminus is imp

227 his study, we show that phosphorylation of a serine residue (S165) within the groove of influenza A v

228 ere we show that phosphorylation of a single serine residue (S2844) in the sarcoplasmic reticulum (SR

229 es phosphorylated on at least one regulatory serine residue (S320).

230 f the STEVOR C-terminal domain at a specific serine residue (S324).

231 Two neighboring serine residues, S349 and S351, are required for the ace

232 s desensitized by GRK phosphorylation at two serine residues (S426 and S430).

233 wever, RelA phosphorylation, particularly at serine residues S536 and S276, is critical for RelA func

234 ing that phosphorylation of GluA1 C-terminal serine residues S831 and S845 is not required for CaN in

235 n addition, APE2 associates with Chk1, and a serine residue (S86) in the Chk1-binding motif of APE2 i

236 tor domain by the kinase JNK3 at a conserved serine residue (Ser-175 in the B isoform and Ser-176 in

237 ntaining an aspartic acid substitution for a serine residue (Ser-189) that in GRASP65 is phosphorylat

238 hosphatase-1-mediated dephosphorylation of a serine residue (Ser-9) preceding the GIRK2 Val-13/Leu-14

239 ation of stathmin on one or more of its four serine residues (Ser(16), Ser(25), Ser(38), and Ser(63))

240 ction, MAPK phosphorylation of the preceding serine residues (Ser(P)(279)and Ser(P)(282)) increases t

241 rylation, the phosphorylation of a conserved serine residue, Ser(779), can quantitatively control Ras

242 terized several mutants of the corresponding serine residue, Ser-364, of human glutamate transporter

243 that allows ERK phosphorylation at a second serine residue, Ser-96.

244 hat PKD1 directly phosphorylates VASP at two serine residues, Ser-157 and Ser-322.

245 ed out in Pcyt2beta and on two PKC consensus serine residues, Ser-215 and Ser-223.

246 at CK2 directly phosphorylates Dzip1 at four serine residues, Ser-664/665/706/714.

247 imuli promote Hsp27 phosphorylation on three serine residues--Ser(15), Ser(78), and Ser(82)-by a numb

248 f the MIA group from NosJ-MIA to a conserved serine residue (Ser102) on NosK.

249 s containing HSP27 mutated at three critical serine residues (Ser15, Ser78, and Ser82) to either alan

250 we investigated the roles of three conserved serine residues [Ser198(5.42), Ser199(5.43), and Ser202(

251 ing distance of the side chain hydroxyl of a serine residue (Ser201) that is conserved in both HMS an

252 s from the hearts of mice in which the three serine residues (Ser273, Ser282, and Ser302) that are ph

253 implicate the phosphorylation of a specific serine residue (Ser322) on the synaptic protein UNC-18 a

254 bits increased phosphorylation of a critical serine residue (Ser354) and higher protein expression as

255 CD4 (programmed cell death protein 4) on two serine residues (Ser76 and Ser457) that regulate its sub

256 ependent phosphorylation of Hof1 at a single serine residue (serine 313) in this region diminishes th

257 Here we show that PKC phosphorylates a serine residue situated within a phospholipid binding mo

258 has been shown to be phosphorylated on three serine residues, specifically serine residues 16 and 18,

259 as determined to predominantly phosphorylate serine residues, specifically serine-18 in OLE3.

260 as been measured biochemically at C-terminal serine residues, suggesting that these residues are crit

261 tamine followed by a stretch of threonine or serine residues, suggesting the presence of structural r

262 t inhibition of p65 phosphorylation on these serine residues targets NF-kappaB activity to distinctiv

263 contains the C-terminal ITIM tyrosine and a serine residue that undergo activation-dependent phospho

264 This region contains eight serine residues that are highly conserved among HCV isol

265 egion on which lie two functionally critical serine residues that are phosphorylated during infection

266 gion of alpha7 contains an acidic patch with serine residues that are phosphorylated.

267 issociation is prevented by mutation of four serine residues that are potential sites of phosphorylat

268 on of the B55alpha subunit itself on several serine residues that drastically increases the affinity

269 Mass spectrometry identified two unique serine residues that were phosphorylated by Plk3.

270 ter mutation of the putative phosphoacceptor serine residues, the localization of the E2 protein was

271 nes through phosphorylation of different p65 serine residues, thus shedding light on novel mechanisms

272 of RdmB and show that insertion of a single serine residue to DnrK is sufficient for introduction of

273 sphorylates PYL ABA receptors at a conserved serine residue to prevent activation of the stress respo

274 he transcription factor Gata6 on a conserved serine residue to promote neural crest migration and pro

275 ally phosphorylated on specific tyrosine and serine residues to acquire full transcriptional activity

276 ammatory cytokines that target COOH-terminal serine residues to activate ubiquitination and protein d

277 rom homology modeling, mutation of three TM5 serine residues to alanine (S5.42A, S5.43A, S5.46A) had

278 Mutation of these serine residues to alanine (S617A and S1179A) inhibited

279 ctivation, acting through N-terminal phospho-serine residues to regulate GR recruitment to its target

280 sphate precipitate core of LCP, two phosphor-serine residues were added to the N-terminal of the pept

281 enotype 1b Con1 NS5A, we found that specific serine residues were important for efficient hyperphosph

282 s known to phosphorylate PDX-1 on C-terminal serine residues, which triggers PDX-1 proteasomal degrad

283 C-terminal domain of p53 through two unique serine residues, which were acquired during recent verte

284 e specifically phosphorylates the C-terminal serine residue while ignoring those located elsewhere.

285 Replacement of these serine residues with acidic residues, to mimic phosphory

286 sitides but undergoes phosphorylation on the serine residue within a CaMKII target motif.

287 a PXXYHXXHXP motif, and a uniquely conserved serine residue within a GS(S/T) motif, suggesting that P

288 , by phosphorylating a specific threonine or serine residue within the activation loop which is criti

289 We identified a conserved serine residue within the C terminus of CBLs as being ph

290 region (S4-S6) of TRPC4 predicts a conserved serine residue within the C-terminal sequence of the pre

291 nase A-dependent phosphorylation of a single serine residue within the core of the polybasic domain,

292 We showed that mutations in the serine residues within and outside the serine cluster di

293 Autophosphorylation of serine residues within TbetaRII is considered the princi

294 In both cases, in vitro phosphorylation of serine residues within the acidic tail stabilizes the as

295 Unexpectedly, mutation of serine residues within the activation segment of PINK1 u

296 forming a complex that dephosphorylates two serine residues within the catalytic domains of IkappaB

297 cultured cells, phosphorylation of specific serine residues within the cluster is also required for

298 stem enables us to map the O-linkages to the serine residues within the first SRR of PsrP.

299 at GSK-3beta phosphorylated two stretches of serine residues within the nuclear export signal and the

300 basal conditions, whereas phosphorylation of serine residues within three amino-terminal protein kina