ライフサイエンスコーパス: seryl-tRNA

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1 s not present upstream of either copy of the seryl-tRNA(CAG) gene in eight other laboratory strains o

2 (which we designate beta) 9bp upstream of a seryl-tRNA(CAG) gene in the genome of Candida albicans.

3 There are two copies of the seryl-tRNA(CAG) gene, one on each homologue of chromosom

4 e searched for unique structural features in seryl-tRNA(CAG), which translates the leucine CUG codon

5 d that the role of this enzyme is to provide seryl-tRNA for the valanimycin biosynthetic pathway.

6 s of investigations to elucidate the role of seryl-tRNA in valanimycin biosynthesis.

7 nticodons are aminoacylated with serine, the seryl-tRNA is converted to selenocysteyl-tRNA and the la

8 Its biosynthesis from seryl-tRNA(Sec) has been established for bacteria, but t

9 ated that MJ0158 lacked affinity for E. coli seryl-tRNA(Sec) or M. jannaschii seryl-tRNA(Sec), and ne

10 se and demonstrated that the enzyme converts seryl-tRNA(Sec) to O-phosphoseryl-tRNA(Sec) that could c

11 Bacterial selenocysteine synthase converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) for selenop

12 enocysteine synthase converted both types of seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec).

13 for E. coli seryl-tRNA(Sec) or M. jannaschii seryl-tRNA(Sec), and neither substrate was directly conv

14 cifically phosphorylated the seryl moiety on seryl-tRNA[Ser]Sec and, in addition, had a requirement f

15 Using the ACC domain of seryl tRNA synthetase (SRS-ACC) as a scaffold for protei

16 oding a flavin monooxygenase (vlmH, vlmR), a seryl tRNA synthetase gene (vlmL ) and seven genes of un

17 By positional cloning, we isolated seryl-tRNA synthetase (sars) as the gene affected by the

18 One example is the UNE-S domain, appended to seryl-tRNA synthetase (SerRS) in species that developed

19 cent studies suggested an essential role for seryl-tRNA synthetase (SerRS) in vascular development.

20 ix substrates revealed that Escherichia coli seryl-tRNA synthetase (SerRS) recognizes the 1--72 throu

21 utotrophicum contain a structurally uncommon seryl-tRNA synthetase (SerRS) sequence and lack an open

22 ires three steps: serylation of tRNA(Sec) by seryl-tRNA synthetase (SerRS), phosphorylation of Ser-tR

23 f Sec-specific tRNA (tRNA(Sec)) catalyzed by seryl-tRNA synthetase (SerRS)-is unclear.

24 First seryl-tRNA synthetase acylates tRNA(Sec) with serine to

25 d-coil base provided by Thermus thermophilus seryl-tRNA synthetase and tested these chimeric construc

26 c) is initially aminoacylated with serine by seryl-tRNA synthetase and the resulting seryl moiety is

27 Seryl-tRNA synthetase induced migration of CCR3-transfec

28 The Km of Sec tRNA and serine tRNA for seryl-tRNA synthetase is 6.67 and 9.45 nM, respectively.

29 ass II enzymes, aspartyl-tRNA synthetase and seryl-tRNA synthetase, do not edit any of the amino acid

30 thase SelA converts Ser-tRNA(Sec), formed by seryl-tRNA synthetase, to Sec-tRNA(Sec).

31 nce of a gene (vlmL) that encodes a class II seryl-tRNA synthetase.

32 a seryl-thioribosyl pyrimidine that targets seryl-tRNA synthetase.

33 ucture of tRNA(Ser) and Thermus thermophilus seryl-tRNA synthetase.

34 rising the long helical arm of the bacterial seryl tRNA synthetases (SRS).

35 genes encoding proteins that are similar to seryl-tRNA synthetases (SerRSs).

36 In contrast, both archaeal and bacterial seryl-tRNA synthetases were able to charge both archaeal

37 tRNA was found in rooster liver, and a minor seryl-tRNA that decoded the nonsense UGA was detected in

38 ivity that phosphorylated a minor species of seryl-tRNA to form phosphoseryl-tRNA was found in rooste

39 lyzes the transfer of the seryl residue from seryl-tRNA to the hydroxyl group of isobutylhydroxylamin

40 phosphoseryl-tRNA and the minor UGA-decoding seryl-tRNA were subsequently identified as selenocystein

41 mL in valanimycin biosynthesis is to produce seryl-tRNA, which is then utilized for a subsequent step

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