ライフサイエンスコーパス: small intestine

1 ides, suggestive of a role for TM6SF2 in the small intestine.

2 then contrasted with what is known about the small intestine.

3 not previously demonstrated in the mammalian small intestine.

4 nce of segmented filamentous bacteria in the small intestine.

5 n spectra compared to those of the colon and small intestine.

6 olon cancer, being largely restricted to the small intestine.

7 and subsequent protein digestibility in the small intestine.

8 cause significant lipid accumulation in the small intestine.

9 inflammatory cytokines and Th17 cells in the small intestine.

10 e distribution of metformin in the liver and small intestine.

11 ntly more tumors in the colon and the entire small intestine.

12 nvironmental samples, mouse feces, and mouse small intestine.

13 nct gluten-degradation patterns in the mouse small intestine.

14 mas, while the bulk of the disease is in the small intestine.

15 he transport and absorption of lipids in the small intestine.

16 ver, and a putative target of metformin, the small intestine.

17 liver but did not affect distribution in the small intestine.

18 and reduced expression of granzyme B in the small intestine.

19 ainst microbes and food Ags derived from the small intestine.

20 ddition to increasing markers of AAMs in the small intestine.

21 an digestion processes in mouth, stomach and small intestine.

22 ters and promotes fructose absorption by the small intestine.

23 pancreas ducts where they join and enter the small intestine.

24 of NCR(-) and NCR(+) ILC3 subsets within the small intestine.

25 rofold cells (M-cells) in Peyer's patches of small intestine.

26 , and 7), to deleteLpcat3specifically in the small intestine.

27 nsumption induces expression of Txnip in the small intestine.

28 TG2 as its principal protein partner in the small intestine.

29 lial cells overlying lymphoid tissues in the small intestine.

30 rate-limiting for glucose absorption in the small intestine.

31 mbling the segmentation motor pattern of the small intestine.

32 lack of interference by radioactivity in the small intestine.

33 nsferase (GPAT3) was examined throughout the small intestine.

34 key discoveries regarding stem cells of the small intestine.

35 of hypoglycaemia following infusion into the small intestine.

36 homeostasis on the epithelial surface of the small intestine.

37 ort processes along the vertical axis of the small intestine.

38 the accumulation of genetic mutations in the small intestine.

39 susceptible to IR-induced tissue injury than small intestine.

40 ie many of the phenotypes seen in the mutant small intestine.

41 tty acids and lipid metabolites in the mouse small intestine.

42 immune system, facilitating colonization of small intestine.

43 l role in looping morphogenesis of the avian small intestine.

44 ntestinal tract (GIT) model: mouth; stomach; small intestine.

45 uniquely altered in the chronically inflamed small intestine.

46 d GLP-1 secretion from isolated perfused rat small intestine.

47 ystem, including the esophagus, stomach, and small intestine.

48 g reaching the surfaces between villi in the small intestine.

49 induces a massive secretion of 26RFa by the small intestine.

50 a and colonize the epithelial surface of the small intestine.

51 rpa1 as an L cell-enriched transcript in the small intestine.

52 en and mucosa and moderately with the distal small intestine.

53 s well as inflammation and remodeling of the small intestine.

54 enic Th1 and/or Th17 cell populations in the small intestine.

55 o express SLAMF4 only after migrating to the small intestine.

56 d increased expression of ABCG5 and ABCG8 in small intestine.

57 hich emptied into and progressed through the small intestine.

58 ate of delivery of nutrients to the proximal small intestine.

59 cally lacked FDC-containing GALT only in the small intestine.

60 he primary site of injury, namely the distal small intestine.

61 h1 ChIP-seq datasets from the cerebellum and small intestine.

62 ed in brush-border membranes from kidney and small intestine.

63 a propria phagocytes and inflammation in the small intestine.

64 xpression in organotypic cultures of Ano1 WT small intestine.

65 nt role in maintaining the physiology of the small intestine.

66 ed in loss of slow waves in smooth muscle of small intestine.

67 low levels in the colon as compared with the small intestine.

68 e mouse stomach and colon and from the human small intestine.

69 act with and modulate the environment in the small intestine.

70 y decrease their intracellular levels in the small intestine.

71 d unsaturated fatty acids found in the upper small intestine.

72 ltaneously deleted Chk1 and Apc in the mouse small intestine.

73 y intact anthocyanins were absorbed from the small intestine.

74 tes along the proximal-to-distal axis of the small intestine.

75 g glucose-induced GLP-1 secretion from human small intestine.

76 er cholesterol transporters, in the proximal small intestine.

77 laughter age, but reduces clearance from the small intestine.

78 ed information on survivin expression in the small intestine.

79 , and cholecystokinin (CCK), secreted by the small intestine.

80 irectly by modulation of BMP activity in the small intestine.

81 s immune-mediated inflammatory damage to the small intestine.

82 T cells (T(EM)) found only in the lungs and small intestine.

83 mportantly, no adenomas were observed in the small intestine.

84 in the apical surface of enterocytes in the small intestine.

85 YY (PYY), from enteroendocrine cells in the small intestine.

86 nd food crops was found to be highest in the small intestine.

87 eferentially enzymatically hydrolyzed in the small intestine.

88 postnatal formed lymphoid tissues within the small intestines.

89 sis, are also influenced by vitamin A in the small intestines.

90 ducing microbiota and SCFA production in the small intestines.

91 w lumen, with adaptability to both large and small intestines.

92 both colon (1.5-fold increase, P < 0.05) and small intestine (1.5-fold increase, P < 0.05) after 30 a

93 lso found in the subepithelial region of the small intestine 24h after pollens were gavaged to mice.

94 tly decreased (11)C-donepezil binding in the small intestine (-35%; P = 0.003) and pancreas (-22%; P

95 n was found to be up-regulated in the distal small intestine, a tissue involved in chylomicron synthe

96 In the small intestine, afferent lymphatics convey Ags and micr

97 ls developed exacerbated inflammation in the small intestine after challenge with anti-CD3 antibodies

98 We showed that upregulation of SGLT1 in the small intestine after glucose ingestion is promoted by g

99 (TG) are absorbed by the enterocytes of the small intestine after luminal hydrolysis into monacylgly

100 monstrated that microcapsules released Lf in small intestine allowing 6.5 times higher concentration

101 quitous, but poorly defined, disorder of the small intestine among people living in conditions of pov

102 The increasing pH as the yogurt enters the small intestine and a slower gastrointestinal transit ti

103 s taken up by dendritic cells throughout the small intestine and additionally by F4/80(+) cells in th

104 in primary cultures of enteroids from human small intestine and anion current in enteroid monolayers

105 Survivin could be detected in the small intestine and ascending colon of the normoxia grou

106 all compartments, but first in the stomach, small intestine and ascending colon.

107 vin was detected in the ischemically damaged small intestine and ascending colon.

108 l lines, and animal tissues of cornea, skin, small intestine and bladder.

109 ed by mesenteric ischemia/reperfusion in the small intestine and by dextran sulfate sodium in the col

110 2(IEKO)) led to malignant tumors in both the small intestine and colon in 86% of the mice and to meta

111 on intestinal epithelial cells (IECs) in the small intestine and colon is required for enteric IFN-la

112 We used 3-dimensional small intestine and colon organoids, along with RNA-Seq

113 fferentiation into Th2 and Th17 cells in the small intestine and colon, and inhibits T-cell different

114 known to be a stem cell marker in the murine small intestine and colon, however the localization of L

115 ial alimentary tract, including the stomach, small intestine and colon, was analyzed in normal human

116 oendocrine cells and neurons innervating the small intestine and colon.

117 e, esophagus, and stomach in addition to the small intestine and colon.

118 n the membrane, damaging epithelial cells in small intestine and colon.

119 the intestinal epithelial cells in the host small intestine and has evolved strategies to antagonize

120 th the deep muscular plexus (ICC-DMP) in the small intestine and ICC associated with the submucosal p

121 ice elevated trophozoite colonization in the small intestine and impaired weight gain.

122 er investigate the role of Chk1 in the mouse small intestine and its potential role as a therapy for

123 was used to determine the gastrointestinal (small intestine and liver) retention, and presumably met

124 ved in phosphatidylcholine remodeling in the small intestine and liver.

125 , although is involved in clearance from the small intestine and longer-term clearance from the ceca.

126 nal accessibility during passage through the small intestine and modulated the formation of the degra

127 53,193 individual epithelial cells from the small intestine and organoids of mice, which enabled the

128 Paneth cells reside in the small intestine and produce antimicrobial peptides essen

129 n reduced numbers of parasitic adults in the small intestine and reduced larval output throughout inf

130 in specialized enteroendocrine cells of the small intestine and released by fat ingestion, facilitat

131 the induction of the IL-1beta pathway in the small intestine and reversed by treatment with an exogen

132 GL-3 accumulation in the small intestine and sensory ganglia of Gla KO mice provi

133 y to regulate GI stem cell function in adult small intestine and stomach.

134 ines TNFalpha (TNF), RANKL, and IL-17 in the small intestine and the BM.

135 visceral fat and decreased the length of the small intestine and the circumference of the ileum.

136 on of infection, including both the proximal small intestine and the colon.

137 d to the parental strain was observed in the small intestine and the liver.

138 s are one of 4 secretory cell linages in the small intestine and the source of IL-25, a critical init

139 enterocyte surface in the mid-region of the small intestine and translocate through the epithelial c

140 on-like peptide-1 (GLP-1) is produced in the small intestines and in nucleus tractus solitarius (NTS)

141 ve tract (mouth, throat, esophagus, stomach, small intestine, and colorectum) and digestive accessory

142 e of homeostasis and proper functions in the small intestine, and dysregulated miRNAs and proteins al

143 Isolating the proximal small intestine, and in particular its luminal glucose s

144 art, spleen, liver, kidneys, stomach, colon, small intestine, and pancreas, respectively.

145 lling associated with type 2 immunity in the small intestine, and perhaps at other mucosal barriers p

146 luding the kidney, liver, lung, lymph nodes, small intestine, and spleen, confirmed that reciprocal d

147 r suppressor in the mouse colon, but not the small intestine, and that invasive ARID1A-deficient aden

148 Absorptive and secretory cells of the small intestine are derived from a single population of

149 GALT and of T cells and plasmablasts to the small intestine are well described.

150 oth the mRNA and protein levels revealed the small intestine as the major site of protein expression

151 Ex vivo analysis suggested the small intestine as the site of spore germination.

152 ice had increased expression of Txnip in the small intestine as well as enhanced fructose uptake and

153 ls caused significant mucosal atrophy in the small intestine, as indicated by decreased cell prolifer

154 develop remarkable dilation of the stomach, small intestine, bladder, and ureters attributable to th

155 Since DGAT1 is expressed in the small intestine, both 1 and 9 can suppress postprandial

156 he lung, airways, lamina propria (LP) of the small intestine, brain, visceral adipose tissue, bone ma

157 In the chronically inflamed rabbit small intestine, brush border membrane (BBM) Na-glutamin

158 provides a noninvasive option to assess the small intestine, but its use with respect to endoscopic

159 e III secretion system (T3SS2) to infect the small intestine, but knowledge of additional factors tha

160 s study, we studied PC dynamics in the human small intestine by cell-turnover analysis in organ trans

161 s as models for pathogenic infections in the small intestine by examining whether HIEs from different

162 L. plantarum adapts to the small intestine by expressing genes required for tolerat

163 Lymphatic capillaries of the small intestine, called lacteals, play key roles in diet

164 e number and tightness of loops in the chick small intestine can be increased or decreased directly b

165 microbiome, while age is a driving force for small intestine cancer.

166 sease (CD) is an inflammatory disease of the small intestine caused by an immunologic hypersensitivit

167 iscovered that Giardia's colonization of the small intestine causes a systemic dysbiosis of aerobic a

168 e salts glycocholate and taurocholate in the small intestine causes dimerization of the transmembrane

169 genome-wide mutation patterns in ASCs of the small intestine, colon and liver of human donors with ag

170 or primordial germ cell-like cells and E18.5 small intestine, combined with functional annotation ana

171 reased expression of interferon gamma in the small intestine compared to wild-type mice exposed to sm

172 thesis and decreased bile acid levels in the small intestine compared with wild-type mice.

173 xidant capacities similar to the stomach and small intestine, containing parent compounds.

174 the derived COs represent colon rather than small intestine, containing stem cells, transit-amplifyi

175 The small intestine contains CD4(+)CD8alphaalpha(+) double-p

176 e liver, upper large intestine contents, and small intestine contents between rest and stress imaging

177 Bacteria invade the small intestine, crossing the intestinal epithelium from

178 Analysis of ileal effluents (at end of small intestine) demonstrated that 30% of ingested antho

179 We also show that small intestine dendritic cells from pregnant, but not f

180 The major iron transporters in the small intestine divalent metal-ion transporter 1 (DMT1)

181 duction of this key cytokine by ILC3s in the small intestine during development and under basal condi

182 In small intestine, eating induces endocrine secretion of u

183 nutrient delivery to the proximal and distal small intestine elicits different outcomes.

184 at the slightly alkaline pHs simulating the small intestine environment, suggesting a potential of t

185 FAM7A transcript found in normal human fetal small intestine epithelial (FHs) cells to prove its iden

186 In the small intestine, epithelial cells are derived from stem

187 ence of dendritic cells and TRM cells in the small intestine epithelium also required alphavbeta6.

188 ed in other proliferative tissues, including small intestine epithelium.

189 ce with conditional disruption of Ihh in the small intestine epithelium.

190 suggest that the absorptive capacity of the small intestine for fructose is limited, though the mole

191 g whether HIEs from different regions of the small intestine from different patients are susceptible

192 ct H2O2, protects the mucosal surface in the small intestine from the cholera pathogen.

193 absorbed doses to the upper large intestine, small intestine, gallbladder wall, and lower large intes

194 of the deep muscular plexus (ICC-DMP) in the small intestine generate spontaneous Ca(2+) transients t

195 with the OA patients, more AYA patients had small-intestine GISTs (139 [35.5%] vs 1465 [27.3%], P =

196 Patients with less than 50 cm of small intestine had a cumulative probability of wean of

197 starch (RS), which is not hydrolyzed in the small intestine, has proposed health benefits.

198 of Cajal in the deep muscular plexus of the small intestine (ICC-DMP) are closely associated with va

199 y data from the Cftr-deficient colon and the small intestine identified dysregulated genes that belon

200 entified a transcriptional program shared by small intestine ILCs and a core ILC signature.

201 ls in stool as a means to surveil the distal small intestine in a murine model of NSAID enteropathy.

202 cts of myenteric neurons and the wall of the small intestine in mice fed a HFD.

203 e roles of these cells in homeostasis of the small intestine in mice.

204 d on T lymphocytes mediates migration to the small intestine in response to a gradient of CCL25.

205 ne surveillance is distinct from that of the small intestine in terms of draining LNs, and identify p

206 an velocity of the magnetic pill through the small intestine in the fasting state was not significant

207 etary lipids are efficiently absorbed by the small intestine, incorporated into triglyceride-rich lip

208 s is further demonstrated ex vivo by using a small-intestine infection model.

209 changes in the myenteric innervation of the small intestine, intestinal wall and mucosal cells respo

210 phosphate ions are secreted from the distal small intestine into the lumen.

211 The small intestine is a dynamic and complex organ that is c

212 The ability to colonize the small intestine is essential for enterotoxigenic Escheri

213 ic cells (FDC) in the Peyer's patches in the small intestine is essential for the efficient spread of

214 LT1 abundance in the luminal membrane of the small intestine is increased.

215 The small intestine is void of aquaporins adept at facilitat

216 As fat-containing chyme enters the small intestine, it causes the formation of anorexic lip

217 riphery, particularly to Peyer's patches and small intestine lamina propria, where they upregulate LA

218 l dysbiosis alters immune homeostasis in the small intestine, leading to an increase in regulatory T

219 Biliary and small intestine levels of PhIP metabolites were reduced

220 haalpha MAIT cells are enriched in the fetal small intestine, liver and lung.

221 h tumors of the stomach and small intestine, small-intestine location was associated with improved su

222 images with thickened walls adjacent to the small intestine loops, and increase in the echogenicity

223 Importantly, small intestine Lpcat3 deficiency has a much bigger effe

224 Thus, inhibition of small intestine Lpcat3 might constitute a novel approach

225 Moreover, these data indicate that small intestine metabolic dysfunction is accompanied wit

226 ems TM6SF2 deficiency resulted in defects in small intestine metabolism in response to dietary lipids

227 t but rather inhibiting gastric emptying and small intestine motility and strongly suggest the involv

228 stasis, and basic functions performed by the small intestine need to be tightly preserved to maintain

229 agnosis and treatment of well differentiated small intestine neuroendocrine tumors (SI-NET).

230 conjugates of insulin were absorbed from the small intestine of anaesthetised rats by means of the bi

231 observed an enlarged Th17 population in the small intestine of C57BL/6.IgA(-/-) mice compared with w

232 esent study, primary IECs were isolated from small intestine of C57BL/6J mice fed a low-fat diet (LFD

233 C57BL/6 mice with bacteria isolated from the small intestine of CD patients or healthy controls, sele

234 at an HFD promotes tumour progression in the small intestine of genetically susceptible, K-ras(G12Din

235 reased segmented filamentous bacteria in the small intestine of IgA(-/-) mice.

236 f both NCR(-) and NCR(+) ILC3 subsets in the small intestine of mice raised on a vitamin A-deficient

237 sion levels were determined in the liver and small intestine of neonatal hUGT1 mice that were orally

238 NS progenitors from tunica muscularis of the small intestine of newborn (postnatal day 0) wild-type C

239 We analyzed human proteins present in the small intestine of patients infected with V. cholerae O1

240 transglutaminase 2 (TG2) are abundant in the small intestine of patients with active celiac disease (

241 iardia colonization and proliferation in the small intestine of the host may, however, disrupt the ec

242 tion, bleeding, and oedema in the stomach or small intestine of wild-type (WT) mice; however, such se

243 Anti-CD3 aggravated inflammation in the small intestines of Slamf4(-/-) mice and Eat2a(-/-)Eat2b

244 ng digestion in the upper tract (stomach and small intestine) of healthy adult humans.

245 In the small intestine or colon, deletion of upstream Hippo pat

246 n were measured using a pH-sensitive dye and small intestine perfusion, respectively.

247 helial and lamina propria lymphocytes of the small intestine, Peyer's patches, and mesenteric lymph n

248 mall droplets were fully digested within the small intestine phase, and led to a higher bioaccessibil

249 ethylated cytosine residues in the colon and small intestine, probably reflecting their high ASC divi

250 nstration of OCT-mediated transport into the small intestine provides evidence of direct effects of m

251 We found that residence in the small intestine, rather than bacterial identity, dictate

252 The vertebrate small intestine requires an enormous surface area to eff

253 stinct CD4(+) T cell subsets in SLOs and the small intestine, respectively (C.

254 (SLOs) and within the lamina propria of the small intestine, respectively (C.

255 n, inducing cGMP signaling in colorectum and small intestine, respectively.

256 g of dietary triacylglycerol in the proximal small intestine results in physiological, hormonal and b

257 Finally, in vitro experiments on mouse small intestine show that SGLT1 accounts for two-thirds

258 the homeostatic regulation of Mvarphi in the small intestine (SI) remains unclear.

259 Within the murine small intestine (SI), an activating mutation of beta-cat

260 nt DCs had reduced numbers of T cells in the small intestine (SI), but not large intestine (LI), incl

261 ied four distinct Mf subpopulations in human small intestine (SI).

262 6SF2 is expressed predominantly in liver and small intestine, sites for triglyceride-rich lipoprotein

263 AYA patients with tumors of the stomach and small intestine, small-intestine location was associated

264 e expression in ILCs and NK cells from mouse small intestine, spleen and liver, as part of the Immuno

265 term expansion of adult primary tissues from small intestine, stomach, liver and pancreas into self-a

266 ecovery of viable virus from mouse feces and small intestine suggest that these pests may play a role

267 f TM6SF2 protein being 10-fold higher in the small intestine than in the liver, dietary lipid absorpt

268 Celiac disease (CD) is a disease of the small intestine that occurs in genetically susceptible s

269 The development of in vitro artificial small intestines that realistically mimic in vivo system

270 In the small intestine, the epithelium consists of at least fiv

271 ts pro-apoptotic activity in mouse thymi and small intestines, the chromosomal instability caused by

272 lood via inhibition of its absorption in the small intestine, thus protecting against heart attack an

273 3 to -607 of the proximal Npc1l1 promoter in small intestine tissues from 24-week-old offspring fed e

274 cell confocal imaging or by cytofluorometry; small intestine tissues were analyzed by histology and i

275 ; levels of SLAMF4(+) cells were measured in small intestine tissues.

276 gh the delivery of nutrients into the distal small intestine to promote satiety and suppress food int

277 Whereas E. hirae translocated from the small intestine to secondary lymphoid organs and increas

278 used stem cell-derived enteroids from human small intestines to study enterovirus infections of the

279 ptosis in the myenteric ganglia of the adult small intestine, total myenteric neuronal numbers remain

280 We achieved full aPKC down-regulation in small intestine villi and colon surface epithelium using

281 tagenicity in site-of-contact tissues (e.g., small intestine) was generally more than dose-additive a

282 Small-intestine wash fluid (SIWF) was collected for anal

283 Next, focusing on the developing chick small intestine, we determined that Bmp2 expressed in th

284 e of the lysophosphatidic acids (LPA) in the small intestine were also increased in response to UFP e

285 on, animals were euthanized and stomachs and small intestines were processed as whole mounts (submuco

286 intricate organs (esophagus, lung, liver and small intestine) were imaged with x-ray phase contrast c

287 s expressed at the crypt base throughout the small intestine, where it is enriched in crypt base colu

288 rtening, and inflammatory responses in mouse small intestine, whereas administration of D-4F attenuat

289 b(+)CD103(+) DCs induce Th2 responses in the small intestine, whereas CD11b(+)CD103(-) DCs perform th

290 wever, little is known about its role in the small intestine, which absorbs and senses nutrients.

291 for downregulation of glucose absorption in small intestine, which has been proposed as strategy for

292 cer tumors have yielded mostly cancer of the small intestine, which rarely occurs in humans.

293 HRH in T1D may improve GLP-1 function in the small intestine, which, in turn, diminishes TRL and redu

294 Streptococcus) were found in the stomach and small intestine, while anaerobic Lachnospiraceae and Rum

295 genesis, is expressed by Paneth cells in the small intestine, while group X sPLA2 is expressed by Pan

296 mulated cholecystokinin (CCK) hormone in the small intestine, while ILDR1 in EpH4 mouse mammary epith

297 to increased nutrient delivery to the lower small intestine with release of satiety-promoting gut ho

298 ocrine cells in both crypts and villi of the small intestine, with no changes observed in goblet or P

299 , permitting proper placement of the lengthy small intestine within the confines of the body cavity.

300 ganisms immotile, thus they pass through the small intestine without colonizing.