ライフサイエンスコーパス: small nuclear

1 e in the levels of regulatory ncRNAs such as small nuclear and nucleolar RNAs (snRNAs and snoRNAs).

2 Small nuclear and nucleolar RNAs that program pre-mRNA s

3 dding far-red light led to the appearance of small nuclear bodies containing phyB.

4 y and YFP-DCL1 fusion proteins colocalize to small nuclear bodies similar to Cajal bodies but lacking

5 The appearance of small nuclear bodies was rapid, stable, and reversible u

6 of lemurs employed limited mitochondrial or small nuclear data sets, with many relationships poorly

7 at co-segregates with a disease phenotype in small nuclear families, from genome-wide oligonucleotide

8 ter irradiation, CENP-A is found in multiple small nuclear foci that are mutually exclusive to gammaH

9 In contrast, many unicellular organisms with small nuclear genomes seem to have lost entirely the RNA

10 highly conserved pathway that converges on a small nuclear group in the lateral aspect of the medial

11 ys an integral role in catalytic, ribosomal, small nuclear, micro, and transfer RNAs.

12 Hundreds of small nuclear non-coding RNAs, including small nucleolar

13 croRNAs (miRNAs), Piwi-interacting (piRNAs), small nuclear, nucleolar, cytoplasmic (sn-, sno-, scRNAs

14 ed with highly expressed histone genes and U small nuclear or nucleolar RNA (sn/snoRNA) loci that for

15 n and increase the number of nuclear 'gems', small nuclear organelles in which survival motor neuron

16 GRD encodes a small nuclear protein of the RWP-RK family and is broadl

17 We have investigated recruitment of U1 small nuclear ribonuclear protein (snRNP) by G1M2 and IS

18 phase and causes dramatic disorganization of small nuclear ribonuclear protein and serine-arginine ri

19 In yeast, the U2 small nuclear ribonucleic acid (snRNA) component of the

20 ned that RBM20 interacts with both U1 and U2 small nuclear ribonucleic particles (snRNPs) and suggest

21 ibute to a better understanding of Gemin5 in small nuclear ribonucleic protein (snRNP) biogenesis as

22 he present study, we characterized U1-70-kDa small nuclear ribonucleoprotein (70-kDa) autoantigen-spe

23 It exists in inactive small nuclear ribonucleoprotein (7SK snRNP) and active (

24 ) kinase, which is suppressed within the 7SK small nuclear ribonucleoprotein (7SK snRNP).

25 We show that newly assembled small nuclear ribonucleoprotein (RNP [snRNP]) particles,

26 esting an unknown quality control system for small nuclear ribonucleoprotein (snRNP) assembly.

27 SMN is critical for small nuclear ribonucleoprotein (snRNP) assembly.

28 which were associated with an improvement in small nuclear ribonucleoprotein (snRNP) assembly.

29 compared with SMN likely leading to loss of small nuclear ribonucleoprotein (snRNP) assembly.

30 We previously showed that U1 small nuclear ribonucleoprotein (snRNP) associates with

31 RE consists of a single 9-nucleotide (nt) U1 small nuclear ribonucleoprotein (snRNP) base pairing sit

32 Definition occurs by U1 small nuclear ribonucleoprotein (snRNP) binding the 5' S

33 U6 small nuclear ribonucleoprotein (snRNP) biogenesis is es

34 urney to the spliceosome.The mechanism of U6 small nuclear ribonucleoprotein (snRNP) biogenesis is no

35 Nuclear import is an essential step in small nuclear ribonucleoprotein (snRNP) biogenesis.

36 trates within Cajal bodies (CBs) and impacts small nuclear ribonucleoprotein (snRNP) biogenesis.

37 stered into a transcriptionally inactive 7SK small nuclear ribonucleoprotein (snRNP) by the coordinat

38 Interestingly, canonical CB foci and coilin/small nuclear ribonucleoprotein (snRNP) co-localization

39 eoli and bound what we believe to be a novel small nuclear ribonucleoprotein (snRNP) complex composed

40 Autoantibody response against the small nuclear ribonucleoprotein (snRNP) complex is a cha

41 binds 7SK RNA and, as a component of the 7SK small nuclear ribonucleoprotein (snRNP) complex, is recr

42 se mice do not develop autoantibodies to the small nuclear ribonucleoprotein (snRNP) complex.

43 atalytically inactive state bound to the 7SK small nuclear ribonucleoprotein (snRNP) complex.

44 ol II) once released from the inhibitory 7SK small nuclear ribonucleoprotein (snRNP) complex.

45 ) complex is essential for the biogenesis of small nuclear ribonucleoprotein (snRNP) complexes in euk

46 many splicing factors, including the key U2 small nuclear ribonucleoprotein (snRNP) component SF3B1

47 spliceostatin A, sudemycin E binds to the U2 small nuclear ribonucleoprotein (snRNP) component SF3B1.

48 The small nuclear ribonucleoprotein (snRNP) core domain, act

49 In eukaryotes, U1 small nuclear ribonucleoprotein (snRNP) forms spliceosom

50 ous nuclear ribonucleoproteins (hnRNPs), and small nuclear ribonucleoprotein (snRNP) particles throug

51 The 7SK small nuclear ribonucleoprotein (snRNP) plays a central

52 novo motif analysis shows PAS signals and U1 small nuclear ribonucleoprotein (snRNP) recognition site

53 The 7SK small nuclear ribonucleoprotein (snRNP) sequesters and i

54 nisms that regulate P-TEFb involving the 7SK small nuclear ribonucleoprotein (snRNP), factors that co

55 is inhibited by HEXIM1 or HEXIM2 in the 7SK small nuclear ribonucleoprotein (snRNP), which contains,

56 ctions of individual SR proteins with the U1 small nuclear ribonucleoprotein (snRNP)-associated 70-kD

57 In Caenorhabditis elegans, the small nuclear ribonucleoprotein (snRNP)-associated prote

58 Both the BBR and BPS interact with the U2 small nuclear ribonucleoprotein (snRNP)-associated SF3b

59 eins or release P-TEFb from the inactive 7SK small nuclear ribonucleoprotein (snRNP).

60 ylating the RNA, likely by competing with U1 small nuclear ribonucleoprotein (snRNP).

61 as a base-paired complex within the U4/U6.U5 small nuclear ribonucleoprotein (tri-snRNP).

62 in the assembly of spliceosomal uridine-rich small nuclear ribonucleoprotein (U snRNP) complexes coul

63 he early spliceosome assembly begins with U1 small nuclear ribonucleoprotein (U1 snRNP) binding to th

64 n the disease, including U1-70K and other U1 small nuclear ribonucleoprotein (U1 snRNP) spliceosome c

65 the U1 small nuclear RNA component of the U1 small nuclear ribonucleoprotein (U1 snRNP) splicing fact

66 components of the spliceosomal subcomplex U1 small nuclear ribonucleoprotein (U1 snRNP).

67 The U1-small nuclear ribonucleoprotein (U1-snRNP) that includes

68 Binding of U1 small nuclear ribonucleoprotein (U1snRNP) to DM20 is gre

69 SF3B1), a key spliceosomal protein of the U2 small nuclear ribonucleoprotein (U2 snRNP).

70 The auxiliary factor of U2 small nuclear ribonucleoprotein (U2AF) facilitates branc

71 to understand the mechanism of SMN-assisted small nuclear ribonucleoprotein assembly and the underly

72 Here we show that GEMIN2, a spliceosomal small nuclear ribonucleoprotein assembly factor conserve

73 pICln, SMN and Gemin5, which are involved in small nuclear ribonucleoprotein assembly, have an import

74 well characterized function in spliceosomal small nuclear ribonucleoprotein assembly.

75 hanced complex A formation and binding of U2 small nuclear ribonucleoprotein auxiliary factor 65 kDa

76 We reveal that the splicing factor U2 small nuclear ribonucleoprotein auxiliary factor 65-kilo

77 PID in the liberation of P-TEFb from the 7SK small nuclear ribonucleoprotein complex (7SK snPNP).

78 ibitor (PSI) and its interaction with the U1 small nuclear ribonucleoprotein complex (snRNP) control

79 rays revealed that serum anti-Smith and anti-small nuclear ribonucleoprotein complex autoantibodies,

80 clin T1 and CDK9 are incorporated in the 7SK small nuclear ribonucleoprotein complex containing the i

81 Its release from the inactive 7SK small nuclear ribonucleoprotein complex is a critical st

82 ncode core components of the spliceosomal U6 small nuclear ribonucleoprotein complex, regulate circad

83 ltimeric complex involved in the assembly of small nuclear ribonucleoprotein complexes (snRNPs).

84 ckdown of proteins associated with different small nuclear ribonucleoprotein complexes and by using t

85 osophila homologue of Prp38p (dPrp38), a tri-small nuclear ribonucleoprotein component, and is requir

86 tein complex with the methylosome components small nuclear ribonucleoprotein D3b (SmD3b) and protein

87 Brr2 enzyme, which is essential for U4/U6 di-small nuclear ribonucleoprotein disruption during splice

88 of PWS carrying a paternal (p) deletion from small nuclear ribonucleoprotein N (Snrpn (S)) to ubiquit

89 x, SF3B3 and SF3B5, that form part of the U2 small nuclear ribonucleoprotein particle (snRNP) are als

90 The mobile U2 small nuclear ribonucleoprotein particle (snRNP) associa

91 Prp24 is a component of the free U6 small nuclear ribonucleoprotein particle (snRNP) but not

92 k9-cyclin T modules from large, inactive 7SK small nuclear ribonucleoprotein particle (snRNP) complex

93 he 5' splice site, and a component of the U2 small nuclear ribonucleoprotein particle (snRNP) complex

94 s shown to promote the recruitment of the U1 small nuclear ribonucleoprotein particle (snRNP) to the

95 early intron recognition factors U2AF and U1 small nuclear ribonucleoprotein particle (snRNP).

96 ) domain of spliceosomal A protein of the U1 small nuclear ribonucleoprotein particle (U1A) interacti

97 esidues 885-2413) in complex with Aar2, a U5 small nuclear ribonucleoprotein particle assembly factor

98 hat SmD1, a core component of the Drosophila small nuclear ribonucleoprotein particle implicated in s

99 ceosome assembly within the mature U2 snRNP (small nuclear ribonucleoprotein particle), and its displ

100 Prp8, a component of the U5 small nuclear ribonucleoprotein particle, crosslinks ext

101 icing in C. merolae may occur without the U1 small nuclear ribonucleoprotein particle.

102 The U1, U2, U4, U5 and U6 small nuclear ribonucleoprotein particles (snRNPs) are e

103 r messenger RNA substrate bound to U1 and U2 small nuclear ribonucleoprotein particles (snRNPs), and

104 Human spliceosomal U1 small nuclear ribonucleoprotein particles (snRNPs), whic

105 by the spliceosome, a complex of five major small nuclear ribonucleoprotein particles (snRNPs).

106 of Sm core structures of spliceosomal U-rich small nuclear ribonucleoprotein particles (UsnRNPs) requ

107 autoreactive B cells that recognize self-Ag small nuclear ribonucleoprotein particles with activated

108 important for the biogenesis of spliceosomal small nuclear ribonucleoprotein particles, but downstrea

109 d the spliceosome, which is composed of five small nuclear ribonucleoprotein particles, U1, U2, U4/U6

110 3), insulin-like growth factor 2 (IGF2), and small nuclear ribonucleoprotein polypeptide N, and the l

111 lation site, independent of the U1 snRNP (U1 small nuclear ribonucleoprotein).

112 nts, FLICE-associated huge protein, Mute, U7 small nuclear ribonucleoprotein, and MPM-2 phosphoepitop

113 nting stable recruitment of the U4/U5/U6 tri-small nuclear ribonucleoprotein, resulting in accumulati

114 mic acid, which releases P-TEFb from the 7SK small nuclear ribonucleoprotein, they turned green.

115 the latter, it is incorporated into the 7SK small nuclear ribonucleoprotein, which contains hexameth

116 -COP protein co-immunoprecipitates with SMN, small nuclear ribonucleoprotein-associated assembly fact

117 SFPS colocalizes with U2 small nuclear ribonucleoprotein-associated factors inclu

118 at sequential addition of the U4/U6 proteins small nuclear ribonucleoprotein-associated protein 1 (Sn

119 rs such as Lsm11, a core component of the U7 small nuclear ribonucleoprotein.

120 ding proteins (RBPs): lupus La and 70-kDa U1 small nuclear ribonucleoprotein.

121 he CB, such as the SMN complex, spliceosomal small nuclear ribonucleoproteins (RNPs), small nucleolar

122 spliceosome is a complex machine composed of small nuclear ribonucleoproteins (snRNPs) and accessory

123 dynamic RNA-protein machinery consisting of small nuclear ribonucleoproteins (snRNPs) and non-snRNP

124 Small nuclear ribonucleoproteins (snRNPs) are core compo

125 d are associated with defects in assembly of small nuclear ribonucleoproteins (snRNPs) in vitro.

126 5), which are required for the biogenesis of small nuclear ribonucleoproteins (snRNPs) involved in mR

127 The assembly of metazoan Sm-class small nuclear ribonucleoproteins (snRNPs) is an elaborat

128 sequential recruitment and rearrangement of small nuclear ribonucleoproteins (snRNPs) on a pre-mRNA

129 rected cross-linking with in vitro assembled small nuclear ribonucleoproteins (snRNPs) or spliceosome

130 lear domains important for the biogenesis of small nuclear ribonucleoproteins (snRNPs) which function

131 onents of the spliceosome, U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), contain seven

132 N complex is essential for the biogenesis of small nuclear ribonucleoproteins (snRNPs), the major con

133 on of SMN is as an assembler of spliceosomal small nuclear ribonucleoproteins (snRNPs).

134 splicing, forming the cores of spliceosomal small nuclear ribonucleoproteins (snRNPs).

135 Uridine-rich small nuclear ribonucleoproteins (U snRNPs) are involved

136 bly of RNA-protein complexes of uridine-rich small nuclear ribonucleoproteins (UsnRNPs).

137 uclear domain important to the biogenesis of small nuclear ribonucleoproteins and telomerase, complex

138 evidence indicates that U1-70K and other U1 small nuclear ribonucleoproteins are Sarkosyl-insoluble

139 ntial role in the biogenesis of spliceosomal small nuclear ribonucleoproteins in all tissues.

140 erlying the conversion of soluble nuclear U1 small nuclear ribonucleoproteins into insoluble cytoplas

141 proteins found in the U1 and U2 spliceosomal small nuclear ribonucleoproteins is highly conserved.

142 ormation of aberrant U11- and U12-containing small nuclear ribonucleoproteins that impair the efficie

143 me proteins associated with the uridine-rich small nuclear ribonucleoproteins U2, U5, and U6 and the

144 The U1A/U2B''/SNF family of small nuclear ribonucleoproteins uses a phylogenetically

145 otein that is found in the U1 and U2 snRNPs (small nuclear ribonucleoproteins) of Drosophila.

146 e complexes with stably bound U2, U5, and U6 small nuclear ribonucleoproteins.

147 that are suppressed, at least in part, by U1 small nuclear ribonucleoproteins.

148 ex required for the assembly of spliceosomal small nuclear ribonucleoproteins.

149 rt that LARP7, BCDIN3, and the noncoding 7SK small nuclear RNA (7SK) are vital for the formation and

150 7), methyl phosphate capping enzyme, and 7SK small nuclear RNA (7SK).

151 The small nuclear RNA (snRNA) activating protein complex (SN

152 snRNP) by the coordinated actions of the 7SK small nuclear RNA (snRNA) and hexamethylene bisacetamide

153 uborganelles that nonrandomly associate with small nuclear RNA (snRNA) and histone gene loci in human

154 RNA) splicing requires multiple spliceosomal small nuclear RNA (snRNA) and pre-mRNA rearrangements.

155 The human small nuclear RNA (snRNA) and small cytoplasmic RNA (scR

156 with U1 and U2 gene loci, which produce the small nuclear RNA (snRNA) component of the respective sn

157 The small nuclear RNA (snRNA) components of the spliceosome

158 Promoters for vertebrate small nuclear RNA (snRNA) genes contain a relatively sim

159 The small nuclear RNA (snRNA) genes have been widely used as

160 re highly enriched at RNA Pol II-transcribed small nuclear RNA (snRNA) genes, and the loss of LEC res

161 ed for the transcription of Pol II-dependent small nuclear RNA (snRNA) genes.

162 We probe the structure of low-abundance U12 small nuclear RNA (snRNA) in Arabidopsis thaliana and pr

163 editing in mitochondria of trypanosomes and small nuclear RNA (snRNA) maturation in humans.

164 subunit of a protein complex that regulates small nuclear RNA (snRNA) transcription.

165 for the endonucleolytic cleavage of primary small nuclear RNA (snRNA) transcripts within the nucleus

166 se to the catalytic Mg(2+) site in the U2/U6 small nuclear RNA (snRNA) triplex, and the 5'-phosphate

167 vivo association between coilin and rRNA, U small nuclear RNA (snRNA), and human telomerase RNA, whi

168 cleosides from the 3' end of spliceosomal U6 small nuclear RNA (snRNA), directly catalyzing terminal

169 assembled spliceosomal complex comprising U5 small nuclear RNA (snRNA), extensively base-paired U4/U6

170 all nuclear RNP (snRNP), composed of the 7SK small nuclear RNA (snRNA), MePCE, and Larp7, regulates t

171 RNAP II-transcribed cellular RNAs, including small nuclear RNA (snRNA), small nucleolar RNA (snoRNA),

172 , U-rich sequence called the Sm site in each small nuclear RNA (snRNA), to form the core domain of th

173 the survival motor neuron (SMN) protein, U2 small nuclear RNA (snRNA), U5 snRNA, and the small CB-sp

174 ryotic ribosomal RNA (rRNA) and spliceosomal small nuclear RNA (snRNA), uridines at specific sites ar

175 ng requires 5' splice site recognition by U1 small nuclear RNA (snRNA), which is replaced by U5 and U

176 The small nuclear RNA (snRNA)-activating protein complex (SN

177 The small nuclear RNA (snRNA)-activating protein complex (SN

178 ) protein is essential for the biogenesis of small nuclear RNA (snRNA)-ribonucleoproteins (snRNPs), t

179 wn methyltransferase for the U6 spliceosomal small nuclear RNA (snRNA).

180 lysed at a single catalytic metal site in U6 small nuclear RNA (snRNA).

181 y canonical base-pairing to the 5' end of U1 small nuclear RNA (snRNA).

182 (RRM1) to bind RNA stemloops in U1 and/or U2 small nuclear RNA (snRNA).

183 The auxiliary factor of U2 small nuclear RNA (U2AF) is a heterodimer consisting of

184 f noncoding RNAs, including the uridine-rich small nuclear RNA (UsnRNA) and enhancer RNA (eRNA), and

185 iation of the large inactive P-TEFb:7SK RNP (small nuclear RNA 7SK ribonucleoprotein) complex and the

186 pecially dependent on a functional U2 snRNP (small nuclear RNA [snRNA] plus associated proteins), as

187 no oligonucleotide [MO] and an engineered U7 small nuclear RNA [snRNA]) to correct this splicing defe

188 C-4, the Myb-like DNA-binding subunit of the small nuclear RNA activating protein complex, binds piRN

189 ~160-nt-long RNAs, including spliceosomal U6 small nuclear RNA and a cyclic-di-AMP binding riboswitch

190 The SL RNA is a small nuclear RNA and a trans splicing substrate for the

191 partmentalization by fluorophore-labeling U1 small nuclear RNA and observing its distribution in the

192 recursor, proper 3'-end processing of the U4 small nuclear RNA and some small nucleolar RNAs, and deg

193 tein particles (snRNPs), which consist of U1 small nuclear RNA and ten proteins, recognize the 5' spl

194 exon and a 'U1 domain' that binds to the U1 small nuclear RNA component of the U1 small nuclear ribo

195 ription factor SNAP(C), which binds to human small nuclear RNA core promoter elements and nucleates p

196 NA for post-transcriptional modification and small nuclear RNA duplexes for splicing.

197 Human U6 small nuclear RNA gene transcription by RNA polymerase I

198 lex SNAP(c) is required for transcription of small nuclear RNA genes and binds to a proximal sequence

199 on factor that is required for expression of small nuclear RNA genes.

200 denylated, RNAPII-dependent, uridylate-rich, small nuclear RNA genes.

201 cript; the RNA polymerase III-transcribed U1 small nuclear RNA has the same first four nucleotides as

202 te snoRNA, small Cajal body RNA (scaRNA) and small nuclear RNA in human and mouse cells by convention

203 how that the Gemin5-containing subunits bind small nuclear RNA independently of the SMN complex and w

204 sequesters the 5'ss residues involved in U1 small nuclear RNA interactions, thereby inhibiting excis

205 abilize U6 ACAGAGA stem-pre-mRNA and Brr2-U4 small nuclear RNA interactions.

206 ibonucleoprotein (U1-snRNP) that includes U1-small nuclear RNA is a highly conserved intranuclear mol

207 The 7SK small nuclear RNA is a highly conserved non-coding RNA t

208 inding protein La recognizes UUU-3'OH on its small nuclear RNA ligands and stabilizes them against 3'

209 1 and the SLA1 snoRNP but does not affect U1 small nuclear RNA methylation.

210 The human U6 small nuclear RNA promoter, located 5' of the transcript

211 ngle-guide RNAs that are expressed from a U6 small nuclear RNA promoter.

212 uired for precursor mRNA splicing through U6 small nuclear RNA stabilization.

213 enzymes and a revised model for CTD-mediated small nuclear RNA termination.

214 th and without the association of 7SK RNA, a small nuclear RNA that is bound to approximately 50% of

215 ffects of the mutants on the synthesis of U5 small nuclear RNA were analyzed.

216 two ncRNAs implicated in RNA processing: U1 small nuclear RNA, a component of the spliceosome, and M

217 nucleolar RNA, natural antisense transcript, small nuclear RNA, and small RNA using published dataset

218 irtually any RNA (e.g., mRNA, ribosomal RNA, small nuclear RNA, telomerase RNA and so on).

219 te the suppression of 3' end formation by U1 small nuclear RNA, which is known to bind pre-mRNA at th

220 We identified a zebrafish snapc4 (small nuclear RNA-activating complex polypeptide 4) muta

221 n a unique transcription factor known as the small nuclear RNA-activating protein complex (SNAPc).

222 The small nuclear RNA-activating protein complex SNAP(c) is

223 A, TFIIB, and TFIIH which, together with the small nuclear RNA-activating protein complex, form a tra

224 The Brr2 RNA helicase disrupts the U4/U6 di-small nuclear RNA-protein complex (di-snRNP) during spli

225 ox C/D and H/ACA small nucleolar RNAs and U4 small nuclear RNA.

226 ting its association with the inhibitory 7SK small nuclear RNA.

227 hylation at cap 1 on substrate SL RNA and U1 small nuclear RNA.

228 oncanonical mechanisms of base pairing to U1 small nuclear RNA.

229 l of motor neuron (SMN) complex delivers pre-small nuclear RNAs (pre-snRNAs) to the heptameric Sm rin

230 Expression of modified U1 small nuclear RNAs (snRNA) complementary to the splice d

231 ) hairpins immediately downstream from viral small nuclear RNAs (snRNA).

232 , conditional production of 3'-extensions of small nuclear RNAs (snRNAs) and biogenesis of novel tran

233 It assembles from five U-rich small nuclear RNAs (snRNAs) and over 200 proteins in a h

234 assembles the heptameric Sm protein core on small nuclear RNAs (snRNAs) and plays a critical role in

235 Small nuclear RNAs (snRNAs) are essential factors in mes

236 In animals, most small nuclear RNAs (snRNAs) are synthesized by RNA polym

237 Uridine-rich small nuclear RNAs (snRNAs) are the basal components of

238 Because spliceosomal small nuclear RNAs (snRNAs) bind the substrate, snRNA st

239 ng genes requiring RNAPII for transcription, small nuclear RNAs (snRNAs) display a further requiremen

240 risingly, we found that TOE1 associated with small nuclear RNAs (snRNAs) incompletely processed splic

241 Transcription of genes coding for the small nuclear RNAs (snRNAs) is dependent upon a unique t

242 Cross-links identified in the U4 and U6 small nuclear RNAs (snRNAs) suggest U4/U6 stem I as a Br

243 lass of ubiquitously expressed, uridine-rich small nuclear RNAs (snRNAs) transcribed by RNA polymeras

244 ly involves effects of SmD3 on the levels of small nuclear RNAs (snRNAs) U4 and U5.

245 During their biogenesis small nuclear RNAs (snRNAs) undergo multiple covalent mo

246 the cytoplasm, precursors to specific tRNAs, small nuclear RNAs (snRNAs), and small nucleolar RNAs (s

247 mitations, we previously proposed the use of small nuclear RNAs (snRNAs), especially U7snRNA to shutt

248 As (miRNAs), small nucleolar RNAs (snoRNAs), small nuclear RNAs (snRNAs), piwi-associated RNAs (piRNA

249 ection of fluorescently labeled spliceosomal small nuclear RNAs (snRNAs), target the nascent transcri

250 e assembly of heptameric Sm protein rings on small nuclear RNAs (snRNAs), which are essential for snR

251 es (CBs)-subnuclear compartments enriched in small nuclear RNAs (snRNAs)-and promotes efficient splic

252 ynamic machine composed of both proteins and small nuclear RNAs (snRNAs).

253 bes genes that encode proteins and noncoding small nuclear RNAs (snRNAs).

254 del comprising 30 proteins plus U4/U6 and U5 small nuclear RNAs (snRNAs).

255 Although uridine-rich small nuclear RNAs (U-snRNAs) are essential for pre-mRNA

256 ent within snatched fragments and found that small nuclear RNAs and small nucleolar RNAs contributed

257 results in the misexpression of a variety of small nuclear RNAs and small nucleolar RNAs, an effect t

258 the spliceosome, a macromolecule composed of small nuclear RNAs associated with proteins.

259 is is, however, required for displacement of small nuclear RNAs from the Gemin5-containing subunits a

260 nscribed nucleotide of spliced leader and U1 small nuclear RNAs in the kinetoplastid protozoan Trypan

261 uide covalent modifications of ribosomal and small nuclear RNAs in the nucleus.

262 ntergenic ncRNAs, small cytoplasmic RNAs and small nuclear RNAs show less consistent patterns.

263 for catalysis by unwinding base-paired U4/U6 small nuclear RNAs, a step that must be precisely timed.

264 an intricate network formed by U5, U2 and U6 small nuclear RNAs, and a pre-messenger-RNA substrate.

265 particular spliceosome components, including small nuclear RNAs, cause reproducible uniquely distribu

266 uide chemical modifications of ribosomal and small nuclear RNAs, functions that are carried out in th

267 show that a base-paired complex of U6 and U2 small nuclear RNAs, in the absence of the approximately

268 plex often signals nuclear import for U-rich small nuclear RNAs, it is unclear how this Sm binding si

269 of nucleotides in ribosomal and spliceosomal small nuclear RNAs, respectively.

270 ed abundant small, noncoding RNAs, including small nuclear RNAs, small nucleolar RNAs (snoRNAs), cryp

271 ound in HEXIM1 immunoprecipitates, while the small nuclear RNAs, U6 and U2, were not.

272 it complex required for 3'-end processing of small nuclear RNAs.

273 rimethylguanosine (TMG) caps on spliceosomal small nuclear RNAs.

274 d structural features with cellular Sm-class small nuclear RNAs.

275 ng RNAs, which share some of the features of small nuclear RNAs.

276 S and 28S rRNAs and levels of the U-class of small nuclear RNAs.

277 increases the levels of spliceosomal and U7 small-nuclear RNAs and corrects RNA processing defects i

278 bcutaneously at age 8-12 weeks with U1-70-kd small nuclear RNP (70K) fusion protein along with either

279 ream of the stem-loop and consists of the U7 small nuclear RNP (snRNP) and number of protein factors.

280 FLASH (Flice-associated huge protein) and U7 small nuclear RNP (snRNP) are HLB components that partic

281 ufficient for trans-splicing, which binds U1 small nuclear RNP (snRNP) through strong base-pairing wi

282 The 7SK small nuclear RNP (snRNP), composed of the 7SK small nuc

283 ine methyltransferase, methylates Snp1, a U1 small nuclear RNP (snRNP)-specific protein, and that the

284 mice were immunized with 50 mug of U1-70-kd small nuclear RNP fusion protein and 50 mug of U1 RNA ad

285 ion, in which the D, E, F, and G proteins of small nuclear RNPs (snRNP) but without other components

286 autoantibody ICs containing apoptotic cells, small nuclear RNPs (snRNPs), or DNA, or directly with TL

287 dalton-sized spliceosome is composed of four small nuclear RNPs and additional pre-mRNA splicing fact

288 The U1 small nuclear RNPs are common targets of autoantibodies

289 Small nuclear RNPs were fluorescence-labeled, and the ef

290 or the biogenesis of ribosomes, spliceosomal small nuclear RNPs, microRNAs and the telomerase RNP.

291 ore show that mediator is a basal factor for small nuclear SL RNA gene transcription in trypanosomes

292 The U1 small nuclear (sn)RNA (U1) is a multifunctional ncRNA, k

293 A pseudouridine-modified region of the U2 small nuclear (sn)RNA anneals with the intronic branchpo

294 ereas transcription of small nucleolar (sno)/small nuclear (sn)RNA genes is terminated by the RNA-bin

295 Integrator complex to the Pol II-transcribed small nuclear (sn)RNA genes.

296 The U1 small nuclear (sn)RNA participates in splicing of pre-mR

297 Human U1 small nuclear (sn)RNA, required for splicing of pre-mRNA

298 ction in posttranscriptional modification of small nuclear (sn)RNAs.

299 embrane proteolysis followed by release of a small nuclear-targeted cytosolic fragment.

300 phomas in non-natural hosts, expresses seven small nuclear uracil-rich non-coding RNAs (called HSURs)