ライフサイエンスコーパス: species difference

1 MDA receptor subunits, suggesting a possible species difference.

2 e effect in the rat, indicating an important species difference.

3 al genes on this arm are responsible for the species difference.

4 te antitumor activity, displays a pronounced species difference.

5 dies to better establish the extent of these species differences.

6 ion as being strongly linked to the observed species differences.

7 ich morphological and genetic data concur on species differences.

8 ied before they become confounded with other species differences.

9 nd extinction may play a significant part in species differences.

10 ith both the phenotypic variability and with species differences.

11 ort periods of supra-optimal heat, revealing species differences.

12 e highly dissimilar, and that there are also species differences.

13 selection and the pattern of individual and species differences.

14 response to hyperoxia are most likely due to species differences.

15 ingle-base resolution there are considerable species differences.

16 processes and delay the acceptance of valid species differences.

17 t in onion species to reveal important inter-species differences.

18 Here we attribute the discrepancy to species differences.

19 rcolepsy, including therapeutic drug use and species differences.

20 n the in vivo brain and found no significant species' difference.

21 It is likely, that species differences account for pharmacological differen

22 similar to those in macaque but distinctive species differences also exist.

23 Dramatic species differences also existed in CART peptide distrib

24 ion genes do not seem to have a role in this species difference although D. sechellia is sexually dim

25 Seasonal excretion of this protein, species difference and male-specific expression during t

26 se and human) suggest subtle but fundamental species differences and AD transgene effects.

27 These data reveal important species differences and elaborate cell type requirements

28 nal modifications, links to precursor genes, species differences and relationships with other molecul

29 However, due to potential species differences and the inability of models to fully

30 proteome, followed by normalization of inter-species differences, and Markov clustering.

31 Here, I argue that the origin of species differences, and of novel phenotypes in general,

32 the size and distribution of QTL underlying species differences are complicated by differences in th

33 To determine whether species differences are due to organ-specific rather tha

34 scence confocal microscopy and find that the species differences are profound; the vast majority (>75

35 Interpretations of these evolutionary and species differences as continuities or discontinuities r

36 The difficulty is due to species differences, as the channel does not set the mem

37 s tumor specificity is not attributable to a species difference between human tumor and mouse normal

38 transplantation, demonstrating a substantial species difference between mouse and man.

39 iation in the E3 loop is responsible for the species difference between rat and human BRS-3, and mult

40 l song patterns and may reflect an important species difference between zebra finches and Bengalese f

41 vel approach for the quantification of inter-species differences between mouse, rat and human.

42 Species differences between the RAS of rodents and human

43 cription, formalising and highlighting inter-species differences both in the kinetics and in the regu

44 ypotheses about species coexistence hinge on species differences, but quantifying trait differences a

45 Species differences can originate before reproductive is

46 This species difference contrasts with performance on a tempo

47 Species differences demonstrated the importance of testi

48 mouse islet GPCR atlas has demonstrated that species differences do exist in islet GPCR expression an

49 Such species differences do not appear to exist at the level

50 ween synaptic activity and spike firing, and species differences encourage caution when comparing BOL

51 First, species differences exist in the location of the motoneu

52 Thus, species differences exist in the neuronal organization o

53 dues in proton delivery to QB, although some species differences exist.

54 The data suggest that a species difference exists in the distribution of the hum

55 We confirm that a marked species difference exists in the mechanism of Ang II gen

56 sance variance in genetic diversity owing to species differences, for example, in mutation rates or h

57 es that there are actually rather widespread species differences, for example, in the transmission of

58 importance of distinguishing illusory cross-species differences from the true evolutionary differenc

59 Consistent with this species difference, fusions between catalase A and human

60 nd C6-deficient rabbit blood could be due to species differences governing the susceptibility of plat

61 The reason for these dramatic species differences has remained unclear.

62 Our work thus provides strong evidence that species differences have a critical role in stabilizing

63 dicate that position 5.46 contributed to the species difference in 5-HT(2A) receptor potency observed

64 The results explain the marked species difference in antagonist sensitivity and identif

65 o investigate a potential mechanism for this species difference in AVP receptors, the present study e

66 This may reflect a profound species difference in beta cell regeneration pathways in

67 es for FXR function but may also explain the species difference in bile acids/cholesterol metabolism.

68 least two or three genomic regions, and the species difference in interpulse interval may be oligoge

69 with LAIR-2 rarely occurs, implying that the species difference in LAIR-1 genetic pathways could not

70 Z genes showing the greatest species difference in M:F ratio were concentrated near t

71 In conclusion, this study unveils a species difference in nutrient regulation of the human a

72 s study explores the brain localization of a species difference in one such behavior, the crowing of

73 , we address the possibility that this large species difference in onset latencies is caused experime

74 These findings point to a species difference in ovarian steroid regulation of 5-HT

75 The genetic architecture of the species difference in PCl was investigated previously by

76 Underlying this species difference in susceptibility to apoptosis follow

77 d in the dog model indicates that there is a species difference in the amount of RPE65 required to dr

78 A species difference in the arrangement of AZM relative to

79 Thus, our data show an important species difference in the chemical distinction of inhibi

80 To examine further this apparent species difference in the cholinergic effectors for the

81 Thus, there is a marked species difference in the immunoreactivity of Kv3.1b in

82 IEG expression that we observed represents a species difference in the mechanisms of IEG transcriptio

83 The data also point to an intrinsic cross-species difference in the organization of 5' non-coding

84 These contrasting results suggest a species difference in the perceptionand use of features

85 ality with neural-tube defects, suggesting a species difference in the requirement for RAB23 during e

86 This species difference in the role of ATOH8 is explained in

87 However, there is a species difference in the timing of acquiring Nkx2.2 exp

88 The species difference in this character is therefore polyge

89 dicates that residues 59 and 115 mediate the species difference in Wtx-1 affinity.

90 is the first experimental demonstration that species differences in a complex behavior are built up f

91 be translated to humans given the pronounced species differences in ABCG2/ABCB1 expression ratios at

92 ignals, a process widely assumed to generate species differences in adaptive radiation.

93 The developmental bases for species differences in adult phenotypes remain largely u

94 elate significantly with both individual and species differences in aggression, likely reflecting evo

95 s directed toward rationalizing the observed species differences in AhR sensitivity to TCDD and under

96 vivo work that demonstrated ligand-dependent species differences in AHR1 affinity.

97 Species differences in amplitude of these pH(i) changes

98 upled receptors has been the exploitation of species differences in antagonist potencies.

99 In these areas, therefore, species differences in AVP receptor binding appeared to

100 Species differences in basal cocaine- and amphetamine-re

101 elopmental comparative approach, we assessed species differences in behavior, hypothalamic activity,

102 n inform our understanding of individual and species differences in behavioral mechanisms.

103 receptor gene expression are associated with species differences in behavioral response to centrally

104 that evolutionary models explaining between-species differences in behaviour can be used to understa

105 in lotic food webs is relatively low, though species differences in bioaccumulation patterns are impo

106 We tested the hypothesis that species differences in body size and microhabitat use (a

107 ilure of the cerebrotype measure to identify species differences in brain architecture that are indep

108 ere, we test these assumptions and show that species differences in brain size build memory capacity

109 However, species differences in brain structure and connectivity

110 Hence, while confirming expected inter-species differences in calcium sensitivity due to large

111 rm whether the differences are indeed due to species differences in cardiovascular and/or neural cres

112 Large species differences in CART mRNA distribution were appar

113 Here we report that there are significant species differences in CB2R mRNA splicing and expression

114 hether this functional variability is due to species differences in CCK receptor structure or to alte

115 o observed that there were significant intra-species differences in Cd tolerance of L. plantarum stra

116 These results indicate substantial species differences in CD33 expression patterns and liga

117 The biological basis for regional and inter-species differences in cerebral cortical morphology is p

118 at the connectivity itself could account for species differences in circuit responses to curare.

119 Recently, it was demonstrated that even species differences in complex social behavior may be at

120 This too may be mainly due to species differences in crossbridge kinetics.

121 whether microhabitat use was associated with species differences in CTmax and whether microhabitat wa

122 cesses other than Rleaf were responsible for species differences in CUE's temperature response.

123 ation of CYP2D6 substrates because of marked species differences in CYP2D isoforms.

124 To address the possibility of major species differences in DCN organization, we compared Nis

125 More broadly, it shows how species differences in dispersal and establishment may r

126 Pronounced species differences in distribution were few, although m

127 conformations of FtsZ were related to inter-species differences in domain orientation rather than tw

128 ar to internalization, there are agonist and species differences in down-regulation of kappa-opioid r

129 PE (CRPE) were measured to determine whether species differences in drug transport can be explained o

130 maintenance of reproductive isolation and to species differences in ecologically important traits.

131 cture stability may account for the observed species differences in ecto-ATPase enzymatic properties.

132 phant tusks were scanned and we utilized the species differences in elemental composition to develop

133 Species differences in embryonic development and archite

134 rat ENaC current, indicating that there are species differences in ENaC regulation by protons.

135 min from other species, and this may suggest species differences in epitope specificity for self prot

136 Species differences in female pheromone composition and

137 ing body of research addressing the topic of species differences in fish acoustic signals suggests th

138 Despite some inter-species differences in flipper stroke dynamics or freque

139 ifferences in research methodology and cross-species differences in functional neuroanatomy.

140 This resulted predominantly from species differences in gammaENaC.

141 d mouse have molecular correlates, including species differences in gene expression in subplate, alth

142 Our results highlight species differences in GPR15 regulation and suggest it a

143 dorsal LS is also associated with year-round species differences in grouping in estrildid finches, su

144 tic hydrocarbons, but the role of the AHR in species differences in HAH sensitivity is not well under

145 Our results inform the genetics of species differences in Helianthus and suggest an approac

146 rather than phenolic-based defence, explain species differences in herbivory, leaf lifespan and shad

147 is a significant target of TCDD and support species differences in hs1,2 regulation.

148 (P > 0.05), results consistent with observed species differences in IC(5)(0) values obtained by aggre

149 us represent potential contributors to inter-species differences in immunity.

150 We herein describe sex and species differences in immunoreactivity for tyrosine hyd

151 Species differences in knob asymmetry and overall volume

152 Although species differences in laser effects on photoreceptor bF

153 ls and humans arise not only from underlying species differences in lipoprotein metabolism but also f

154 We show that functional tradeoffs explain species differences in long-term population dynamics tha

155 Both individual and species differences in longevity illustrate the variable

156 nt ectopic recombination within the MSY, and species differences in mating behaviour.

157 ithin-population SGS reflected known between-species differences in mating systems.

158 Species differences in microhabitat use can expose anima

159 Having the advantage of species differences in mouse x human hybrids, we are abl

160 s of cis- and trans-regulatory divergence to species differences in mRNA abundance and translation ef

161 nslation regulatory divergence often buffers species differences in mRNA abundance, such that ribosom

162 -factor regulation might have contributed to species differences in nephron progenitor programs such

163 behavior of male mammals are attributable to species differences in neurochemistry, including differe

164 These species differences in neuropil distribution may offer i

165 These studies suggest that there are marked species differences in NHE3 expression in the distal nep

166 omparable to numbers of genes accounting for species differences in other studies.

167 ifferences also explained a larger number of species differences in overall expression level.

168 Species differences in perception have been linked to di

169 To examine the mechanism determining species differences in peroxisome proliferator response

170 1a genotypes explain both within and between species differences in personality traits of bonobos and

171 ies has been limited in murine models due to species differences in pharmacokinetics and biologic res

172 In this context, knowledge of inter-species differences in physiology is crucial for underst

173 the CRD in PI binding and reveal unexpected species differences in PI recognition that can be largel

174 mutants of the two species further show that species differences in pigment pattern reflect: (1) chan

175 This pattern is concordant with species differences in population density and social spa

176 nt beta3-adrenoceptor, yielding considerable species differences in potency.

177 s generally failed both to take into account species differences in prefrontal function that lead to

178 limited relevance for humans due to between-species differences in pregnancy physiology.

179 e arises as to whether there might be within-species differences in processing speed between photorec

180 n to cause rodent hepatic tumors, the marked species differences in PXR/CAR structure, expression pat

181 ng in human cognitive development [1-4], but species differences in reading human social cues remain

182 ssin-receptor gene expression underlie these species differences in receptor distribution and might p

183 igand efficacy introduces the possibility of species differences in receptor-mediated function, an im

184 In the novel object preference test, no species differences in recognition memory were detected,

185 These results demonstrate that 1) species differences in regional AVP receptor binding are

186 ces in V1a receptor binding sites are due to species differences in regional V1a receptor gene expres

187 ormance in both species, but there were also species differences in relative sensitivity to higher an

188 alization to scleral thickness abolished the species differences in scleral transport.

189 Tissue thickness accounts for the species differences in scleral transport.

190 ss and melanin content significantly reduced species differences in SCRPE transport.

191 and melanin content largely account for the species differences in SCRPE transport.

192 studies provide a molecular understanding of species differences in sensitivity to dioxin-like compou

193 is essential to predicting and interpreting species differences in sensitivity to toxicity caused by

194 These results indicate that there are species differences in sensitivity to TRAIL, and that su

195 The species differences in severity of neurological lesions

196 g the temporal delay to disease onset, broad species differences in severity, and diversity of skelet

197 SK: (1) provides a potential explanation for species differences in SK's antigenicity, (2) demonstrat

198 rm our understanding of individual, sex, and species differences in social behavior later in life.

199 1a receptor is a gene known to be central to species differences in social behavior, including differ

200 eptor distribution and thereby contribute to species differences in social behavior.

201 provide a potential molecular mechanism for species differences in social organization.

202 animal societies and has been implicated in species differences in sociality, the environmental pred

203 To evaluate potential species differences in spatial memory and object recogni

204 These observations suggest that while species differences in spatial memory retention are pres

205 If species differences in spatial scale are taken into cons

206 Studies in macaque and rat suggest species differences in steroid action.

207 temporal] for unresolved harmonics) and that species differences in stimulus resolvability need to be

208 rats and mice suggest an explanation for the species differences in susceptibility to C. neoformans b

209 (QP) theory may be able to account for these species differences in terms of orthogonal versus nonort

210 neuropeptide receptor expression may explain species differences in the ability to form pair bonds.

211 Marked species differences in the actions of UII question its i

212 Large between-species differences in the amount of DNA sequence polymo

213 in receptor distribution is associated with species differences in the behaviors, including pair bon

214 and other primate species that could explain species differences in the capacity for relational reaso

215 These data suggest that species differences in the CCK(A) receptor of rats and m

216 Our results illustrate how species differences in the control of ion-channel gene e

217 hese observations indicate significant inter-species differences in the distribution of D3 receptors.

218 hical locations, there were geographical and species differences in the distribution of resistance de

219 There are major species differences in the effects of aging on aortic co

220 Indeed, we report here that there are strong species differences in the expression and regulation of

221 Our studies have shown that (i) there are species differences in the expression of latent versus a

222 sal clades of placental mammals has produced species differences in the functional types of hemoglobi

223 Species differences in the location of the Ca2+-dependen

224 facilitating exchange, we reveal substantial species differences in the mechanism of VSG diversificat

225 puts to barrel cortex, with implications for species differences in the nature and plasticity of lemn

226 e found in the Hp of all four species and no species differences in the number of NPY cells was obser

227 2) binding among the four species, including species differences in the olfactory bulb, nucleus accum

228 ampus and that their phase may contribute to species differences in the optimal phase for learning.

229 se findings suggest that despite substantial species differences in the organization of hippocampal c

230 following each reversal and did not reflect species differences in the rate of initial discriminatio

231 ns to determine whether there were important species differences in the response to cocaine.

232 emporal dynamics of NO diffusion and suggest species differences in the role of NO in the mushroom bo

233 er or in mouse, and they highlight potential species differences in the role of SP within the SCN cir

234 These findings suggest that species differences in the splicing and expression of CB

235 The findings revealed no quantitative species differences in the three cortical areas examined

236 mouse and rat brain raise the possibility of species differences in the transport of IL-1 across the

237 We found robust species differences in the volume of this new area, meas

238 sed by mutant Pde6h/PDE6H suggest species-to-species differences in the vulnerability of biochemical

239 We conclude sympatric species differences in thermal physiology correspond to

240 Therefore, there may be species differences in these projections that are import

241 However, there are striking species differences in these properties.

242 Species differences in this spatial task appear quantita

243 acting transcription factors, is critical to species differences in tissue-specific TERT expression.

244 Species differences in UBF are utilized to demonstrate t

245 Our study highlights important species differences in Ucn 3 expression, which have impl

246 rie vole receptor gene may contribute to the species differences in vasopressin-receptor expression.

247 interaction was investigated by using cross-species differences in VWF storage.

248 There were also species differences in worker retinue attraction to thre

249 to the core genome that is conserved between species, differences in gene content can be linked to th

250 Winter-specific species differences include a substantial increase of MT

251 enes, the CD33rSiglec genes showed extensive species differences, including expansions of gene subset

252 clear whether these are due to the strain or species differences investigated in the different studie

253 The molecular basis of this species difference is not known.

254 One factor that contributes to the species differences is the bZip protein CES-2.

255 These species differences likely relate to flocking rather tha

256 Since species differences limit the utility of animal tissues

257 This finding is explained by cross-species differences mainly found within domain III (DIII

258 he fundamentals of the Mhc, and defining the species differences makes the model organisms more usefu

259 Species differences may also play a role.

260 We hypothesized that species differences might result from differences in pos

261 e.g., flat structure-activity relationships, species differences, "molecular switches"), have been id

262 tion, potentially accounting for some of the species differences observed in IVIG protection.

263 Nevertheless, distinct species differences occur with regard to the details of

264 A gradient of bacterial species (difference of the sum of the relative abundance

265 in rats than in cats may reflect, in part, a species difference of about 40% in metabolic rates.

266 ric Kir2.x complexes, determine regional and species differences of I(K1) in the heart.

267 ecause divergent findings may reflect actual species differences or arise from discrepancies in techn

268 d inhibitory responses that may be caused by species differences or concentration-dependent effects o

269 mouse and human embryonic stem cells reflect species differences or diverse temporal origins.

270 esearch on speciation, leaving the origin of species differences relatively poorly understood.

271 mperature and pacing rate, and conclude that species differences require only changes in myosin affin

272 e classic neo-darwinian view postulates that species differences result from the accumulation of smal

273 We hypothesized that these species differences result in part from a weak or absent

274 s of killifish, rat, and human CYP1As showed species differences similar to those with TCB, but with

275 or functional studies of this gene, although species differences, such as the reduced CpG island (1.8

276 Thus, these species differences suggest that the human-specific shif

277 ges in puberty and typically more pronounced species differences than other body parts.

278 n this study, we take advantage of the large species difference that exists between human and rat CNT

279 in-like A1 subdomains in fVIII contain inter-species differences that are a result of selective press

280 However, because of the species differences, the findings in EEG should be confi

281 nvestigated at the human enzyme did not show species differences; they displayed high selectivity ver

282 he DM phenotype; because of insulin-receptor species differences, this effect is not seen in mouse mo

283 ategy to inhibit costimulation that exploits species differences using the model of porcine pancreati

284 This species difference was conferred by only one residue in

285 This species difference was due to the absence of delta-lyase

286 To investigate this species difference, we have compared the biochemical pro

287 To explore the molecular basis for these species differences, we analyzed the function of the lig

288 mine how individual differences compare with species differences, we characterize variability in the

289 To understand the molecular basis of the species differences, we constructed two Flag-tagged chim

290 e similar across all grazing treatments, and species differences were maintained in the common-garden

291 Site-by-species differences were not statistically significant.

292 Unexpected species differences were noticed, as BX430 is a potent a

293 ing Lp-PLA(2) are indirect and confounded by species differences; whether Lp-PLA(2) is causal in coro

294 tent showed features indicative of important species differences which may have relevance when consid

295 dies emphasize the importance of considering species differences, which can result from even minor pr

296 ion, short half-lives, and a pharmacokinetic species difference with the greatest exposure measured i

297 The results indicate significant species differences with chimpanzees showing population-

298 or elucidating behavioral and neuroendocrine species differences with regard to catecholamine neurotr

299 odents, these findings highlight significant species differences, with more heterogeneity and the pot

300 Such concentration of cross-species differences within the alpha1 and alpha2 domains