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1 9 +/- 13.3 versus 0.22 +/- 0.14 ng/mL in the systemic circulation).
2 to higher proportions of unconjugated BPA in systemic circulation.
3 ed that all SiO(2) were rapidly cleared from systemic circulation.
4 ted endothelial cells from the pulmonary and systemic circulation.
5 ST6Gal-1 enzymes that are deposited into the systemic circulation.
6 e brain as it regulates drug permeation from systemic circulation.
7  in the leakage of retinal proteins into the systemic circulation.
8  a six-fold increase of ASC frequency in the systemic circulation.
9 biomarkers that can often be detected in the systemic circulation.
10 t synthesize riboflavin and must import from systemic circulation.
11 o not reflect prostacyclin production in the systemic circulation.
12 ould allow larger fat particles to reach the systemic circulation.
13  fracture and bone marrow fat passage to the systemic circulation.
14 o the arrangement of cardiac progenitors for systemic circulation.
15 d postmeiotic germ cell development from the systemic circulation.
16  after nigrosin or ICG was injected into the systemic circulation.
17 y depressed levels of ST6Gal-1 released into systemic circulation.
18 age on glycoproteins on cell surfaces and in systemic circulation.
19  and, ultimately, absorption of Stx into the systemic circulation.
20 ors to tumor cells and provide access to the systemic circulation.
21 semination of virus from the mucosa into the systemic circulation.
22 function and a vasodepressor function in the systemic circulation.
23 odify remodeling of HDL particles within the systemic circulation.
24 e rate of nutrient absorption or delivery to systemic circulation.
25 solute level of HDL-cholesterol found in the systemic circulation.
26  with the first pass of labeled cells in the systemic circulation.
27 .5 and are redistributed into the EP via the systemic circulation.
28 ly, the amount of insulin delivered into the systemic circulation.
29 gical RV and delicate tricuspid valve in the systemic circulation.
30  transformed cells and provide access to the systemic circulation.
31 ion, other sialyltransferases are present in systemic circulation.
32 ological right ventricle (RV) supporting the systemic circulation.
33 rating successful vascular targeting via the systemic circulation.
34 oduce necrotic skin ulcers and spread to the systemic circulation.
35 ticles pass directly from the lungs into the systemic circulation.
36 an activated charcoal filter and then to the systemic circulation.
37 inflammatory response that extended into the systemic circulation.
38 articles (Technegas) were able to access the systemic circulation.
39 ipose tissue TG release fatty acids into the systemic circulation.
40 ein cascades, both within muscle, and in the systemic circulation.
41 ws for shunting of deoxygenated blood to the systemic circulation.
42 d undetectable levels of hREN protein in the systemic circulation.
43 l progenitor cells (EPCs) are present in the systemic circulation.
44  factor (G-CSF) would subsequently enter the systemic circulation.
45 ponse to injury more severe than that of the systemic circulation.
46  are significantly greater than those of the systemic circulation.
47  delivery of the recombinant enzyme into the systemic circulation.
48 ood-brain barrier forms a buffer against the systemic circulation.
49 nd e) release of bacterial products into the systemic circulation.
50 ization of human inflammatory cells into the systemic circulation.
51 acterial or endotoxin translocation into the systemic circulation.
52 mits oxygenated placental blood to the fetal systemic circulation.
53 supplies primary lung tumors arises from the systemic circulation.
54 may provide this organism with access to the systemic circulation.
55 r necrosis factor alpha (TNF-alpha) into the systemic circulation.
56 ed that intact insulin was absorbed into the systemic circulation.
57  oxygen delivery is not the only function of systemic circulation.
58  zebra finches, have been found to enter the systemic circulation.
59 tted increased translocation of LPS into the systemic circulation.
60 is required to maintain CTL responses in the systemic circulation.
61 lymphocytes to lymphoid organs and on to the systemic circulation.
62  induced cytotoxic effects in tissues of the systemic circulation.
63 molecular weight polypeptide hormones in the systemic circulation.
64 ase in the intestine, liver, and also in the systemic circulation.
65 , indicating a widespread involvement of the systemic circulation.
66 t increase adrenocorticotropin (ACTH) in the systemic circulation.
67 s direct access to the embryonic cardiac and systemic circulation.
68 lly administered drugs and peptides into the systemic circulation.
69 holamine concentrations in the pulmonary and systemic circulation.
70 nt delivery of inhaled therapeutics into the systemic circulation.
71 raarterial capillaries and mixing within the systemic circulation.
72 location of lipopolysacharide (LPS) into the systemic circulation.
73 reathing, alimentary reflex function and the systemic circulation.
74 bre endings supplied by the pulmonary versus systemic circulation.
75  which oral glucose is made available in the systemic circulation.
76 unction in vivo, both locally and within the systemic circulation.
77  levels locally within the kidney and in the systemic circulation.
78  or to the periphery via absorption into the systemic circulation.
79 cally increased peptide concentration in the systemic circulation.
80 f the heart is underdeveloped, impairing the systemic circulation.
81 procoagulant factors from the brain into the systemic circulation.
82 d oxygenated left ventricular blood into the systemic circulation.
83 ion allowing their rapid inactivation in the systemic circulation.
84 owing to the leakage of bevacizumab into the systemic circulation.
85 ts a portal of entry for E. coli K1 into the systemic circulation.
86 s of inflammatory and allergic biomarkers in systemic circulation.
87 he postnatal separation of the pulmonary and systemic circulation.
88 ng S. typhimurium from gaining access to the systemic circulation.
89 eabsorbed, supporting its persistence in the systemic circulation.
90 asculature, leading to cytokine release into systemic circulation.
91 endent manner and can escape from the CNS to systemic circulation.
92 eous humor from the intraocular chamber into systemic circulation.
93  small proteins with high affinity and short systemic circulation.
94  may also cross the gut barrier to reach the systemic circulation.
95 draining aqueous humor from the eye into the systemic circulation.
96 rginine into urea in the splanchnic area and systemic circulation.
97 greater extent in the human LA compared with systemic circulation.
98 flux of a metabolite from the hepatocytes to systemic circulation.
99 ON INTO AND FIRST-ORDER ELIMINATION FROM THE SYSTEMIC CIRCULATION.
100 are altered not only locally but also in the systemic circulation.
101 ulmonary circulation and O2 unloading in the systemic circulation.
102  lymphocyte egress from lymphoid organs into systemic circulation.
103 uggish restoration of depressed cerebral and systemic circulations.
104 on, without translocations into pulmonary or systemic circulations.
105 )-mediated vasodilation in the pulmonary and systemic circulations.
106 gic shock intestinal lymph from reaching the systemic circulation abrogated the RBC effects, 2) in vi
107                                          The systemic circulation accommodated to the changes in musc
108 donor blood was transfused via the portal or systemic circulation (according to a randomization proto
109 significantly increased IL-17A in portal and systemic circulation after AKI.
110 oavailable and releases gemcitabine into the systemic circulation after passing through the intestina
111 to both the posterior segment of the eye and systemic circulation, allowing for an excellent therapeu
112 zed in the target tissue, rather than in the systemic circulation alone.
113 oside binding proteins, are cleared from the systemic circulation and also covertly delivered to the
114 lammatory reaction can spread throughout the systemic circulation and also into the central nervous s
115 inal epithelia into the intestinal lumen and systemic circulation and bind to the receptor guanylate
116 ties and global uptake in major organs after systemic circulation and biodistribution.
117 he lung, which may then translocate into the systemic circulation and cause end-organ dysfunction, in
118 tunately, in soluble form they readily enter systemic circulation and cause systemic inflammatory tox
119 s escaped the injection site and entered the systemic circulation and contributed to the systemic tox
120 en they will reintroduce aggregates into the systemic circulation and eliminate or shorten the protec
121 n, the presence of bacterial products in the systemic circulation and heightened inflammatory state.
122 l progenitor cells (EPCs) are present in the systemic circulation and home to sites of ischemic injur
123  with GSK2330672 may reduce BA levels in the systemic circulation and improve pruritus.
124  post-meiotic germ cell development from the systemic circulation and is one of the tightest blood-ti
125  CaO2 is known to regulate blood flow in the systemic circulation and it is suggested that IPAVA may
126 sis-infected pleural space may leak into the systemic circulation and lead to increased systemic HIV-
127 nslocation of bacteria from the gut into the systemic circulation and mortality from sepsis.
128 drugs to minimize confounding effects on the systemic circulation and myocardial contractility.
129  to comprehend the relationships between the systemic circulation and peripheral nerves in health, ad
130                            H-Dots show ideal systemic circulation and rapid distribution and excrete
131 xidant capacity in local vascular tissue and systemic circulation and reduced vascular smooth muscle
132  spread of pneumococci from the brain to the systemic circulation and shaping the immune response, th
133 d excellent ocular pharmacokinetics and poor systemic circulation and showed good efficacy in the las
134 fistula allowed bilious contamination of the systemic circulation and subsequent inoculation with ent
135 talarmin concentrations were detected in the systemic circulation and the cerebrospinal fluid by a ma
136 its an abnormal flux of retinoid between the systemic circulation and the eye tissues.
137 lea is maintained by the barrier between the systemic circulation and the fluids inside the stria vas
138       The liver receives blood from both the systemic circulation and the intestine, and in distincti
139 his may limit the amount of endotoxin in the systemic circulation and the kidney, it results in sever
140 centrations of inflammatory mediators in the systemic circulation and the lungs.
141 remains controversial due to the presence of systemic circulation and the onset of hematopoiesis with
142 ues (periodontitis) can disseminate into the systemic circulation and thereby contribute to atheroscl
143 pable of both responding to infection in the systemic circulation and trafficking to mucosal tissues.
144 synthesized, characterized and evaluated for systemic circulation and tumor transfection.
145 NNK parent compound had disappeared from the systemic circulation, and 45 min after instillation, no
146 e in vascular pressure and resistance in the systemic circulation, and an increase in vascular pressu
147 oxifen, in addition to that occurring in the systemic circulation, and direct interaction of this met
148 epinephrine levels in the coronary sinus and systemic circulation, and drug deposition across the ven
149 ficient uptake of apoptotic cells within the systemic circulation, and early component deficiencies c
150 al cells of the blood-brain barrier from the systemic circulation, and iron subsequently dissociates
151 34(+) cell-lined channels were linked to the systemic circulation, and lactate accelerated cell diffe
152 nic perfusate) the CB chemoreflex, while the systemic circulation, and therefore the CNS and central
153 nce of D-COMP in articular cartilage and the systemic circulation, and to our knowledge, it is the fi
154 ctivation of these compounds once they enter systemic circulation are also discussed.
155 e expression in the SON and secretion in the systemic circulation are altered in rats bearing lesions
156 terbalances the decrease in drug uptake from systemic circulation, as exemplified for cyclophosphamid
157 ole in the effects of glucocorticoids on the systemic circulation at a variety of ages.
158 n dictates directed interactions between the systemic circulation (basolateral) and the retina (apica
159  to suppress tPA's enzymatic activity in the systemic circulation but regenerate its thrombolytic act
160 nhaled corticosteroids are absorbed into the systemic circulation, but the extent to which they have
161 ytes into the bile by Abcc2 or back into the systemic circulation by Abcc3, and that it can be taken
162      Shiga toxins (Stxs) may access the host systemic circulation by absorption across the intestinal
163  the kidney is the major donor of Tyr to the systemic circulation by its conversion of Phe to Tyr.
164 ke), which is reabsorbed and returned to the systemic circulation by the proximal tubule.
165  rapid delivery of ingested glucose into the systemic circulation, by an increase in the dynamic insu
166  liposomes that retain their contents in the systemic circulation can alter the pharmacokinetics of a
167 ducts such as endotoxin translocate into the systemic circulation, decreasing liver disease.
168 ropose a model in which the uptake rate into systemic circulation depends on having hydrophobic drug
169 , was unable to produce sialylated Fc in the systemic circulation, despite the presence of Gal(beta4)
170 ndida-specific cell-mediated immunity in the systemic circulation does not mediate protection against
171 es of polyamines may be rapidly cleared from systemic circulation due to their susceptibility to nons
172 l tension, the release of endotoxin into the systemic circulation during episodes of bacterial infect
173  the first day of life) or from pulmonary-to-systemic circulation (eg, in the presence of severe lung
174 -induced neutrophil chemoattractant-1 in the systemic circulation enhanced neutrophil infiltration, B
175 ining lymph nodes but blocked entry into the systemic circulation following intratumoral injection.
176 lular, and molecular events in the lungs and systemic circulation for 24 h.
177  from the azygous vein and both sides of the systemic circulation from 15 s to 30 min after instillat
178            The release of serotonin into the systemic circulation from metastatic small bowel neuroen
179 fect of RYGB on amino acid appearance in the systemic circulation from orally ingested protein and fr
180  was very low due to elimination on reaching systemic circulation from the vitreous.
181                   In contrast to findings in systemic circulation, GIT1 KO mice had an intact blood-b
182 ated that low effector concentrations in the systemic circulation greatly limited their delivery to t
183 ubble contrast agents, which can opacify the systemic circulation, has improved the ability of echoca
184          Adaptations within the coronary and systemic circulations have been suggested but never demo
185 rom graft-infiltrating cells and appeared in systemic circulation in both the tolerogenic and rejecti
186  with chronic endothelial dysfunction in the systemic circulation in children.
187 e rate of entry of ingested glucose into the systemic circulation in humans.
188 , colon catabolites that could be present in systemic circulation in low muM concentrations, have a p
189 hat soluble TL1A and DcR3 are present in the systemic circulation in patients with active IBD and dec
190 ndothelial progenitor cells (EPCs) enter the systemic circulation in response to cues related to vasc
191 used to deliver a recombinant protein to the systemic circulation in sufficient quantities to evoke a
192                 Retention of substances from systemic circulation in the brain and testes are limited
193 TG exhibit similar alterations in ocular and systemic circulation in the early stages of their diseas
194 isolated systolic hypertension involving the systemic circulation in the elderly, much less is known
195  indicate that endotoxin may be found in the systemic circulation in the majority of humans with sept
196 vasively deliver bioactive proteins into the systemic circulation in therapeutic quantities.
197 lthough they were still quickly cleared from systemic circulation in vivo (t1/2<1h).
198 shment of completely separated pulmonary and systemic circulations in vertebrates.
199 ne protein required for iron export into the systemic circulation, in cooperation with hephaestin (He
200  the tyrosine kinase c-Src's function in the systemic circulation, in particular its role in arterial
201  production in the brain but that GXM in the systemic circulation inhibits migration of PMNL toward I
202                Soluble Klotho present in the systemic circulation inhibits TRPC6 currents in cardiomy
203       These CDDP-BPN were delivered from the systemic circulation into orthotopic F98 gliomas using M
204  carbon particles that have cleared from the systemic circulation into the urine does not exist.
205               Connection of the heart to the systemic circulation is a critical developmental event t
206 ediator sphingosine 1-phosphate (S1P) to the systemic circulation is an essential function of rbc in
207 embryo are unanswered questions, because the systemic circulation is initiated early during embryogen
208 ecifically the translocation of LPS into the systemic circulation, is critical to the induction of cy
209 ignificant escape of the metabolite 3 to the systemic circulation, it avoids the testicular toxicity
210 en the difficulty achieving free drug in the systemic circulation, it is highly likely that the drug
211 f adipose stromal and endothelial cells into systemic circulation leads to their homing to and engraf
212 hat increased clonal T-cell responses in the systemic circulation may contribute to irAEs.
213 slocation of gut microbial products into the systemic circulation might increase because of increased
214 distribution of between the cerebral and the systemic circulation modifies the relationship between M
215  products from the intestinal lumen into the systemic circulation occurs during HIV-1 infection and i
216 0.54 +/- 0.23, and (3) levels of PGE1 in the systemic circulation of </= 78 pg/ml, even at the highes
217 or polyoma middle T, and introduced into the systemic circulation of a mouse can bypass transformatio
218     The ubiquitous expression of GPI and the systemic circulation of anti-GPI immunoglobulin G (IgG)
219  the central nervous system, is found in the systemic circulation of humans at a concentration betwee
220 ministration of activated platelets into the systemic circulation of L-selectin knockout mice restore
221 iologically significant levels of Epo in the systemic circulation of mice.
222 ever, administration of these cells into the systemic circulation of mutant mice could be more advant
223 ative stress were elevated in the retina and systemic circulation of obese and insulin resistant rode
224 cid levels were reduced in portal but not in systemic circulation of obese knockout mice.
225 otein or mRNA levels of the cytokines in the systemic circulation of patients and controls.
226 ion, which would possibly explain reports of systemic circulation of unmetabolized folic acid.
227 inding and clearance of pneumococci from the systemic circulation or reflect limited maturation of th
228 rom which they may be slowly released to the systemic circulation over a prolonged period.
229 pression of IL-10 was upregulated and in the systemic circulation, platelet white blood cell aggregat
230 of copper from the intestine to liver and in systemic circulation probably includes both albumin and
231 ce coating, endowing them with much improved systemic circulation properties and better access to dis
232 sts, SCID mice stably produced hFIX into the systemic circulation proportional to the number of impla
233 lpha within the model despite the absence of systemic circulation, providing a model for inflammatory
234    We tested the hypotheses that, unlike the systemic circulation, pulmonary vascular resistance (R(P
235  microbiome products that gain access to the systemic circulation, rather than being proinflammatory,
236  was present in higher concentrations in the systemic circulation, relative to VEGF.
237 d failure of the right ventricle (RV) in the systemic circulation remain the main contributors to mor
238 d a total exclusion of the aneurysm from the systemic circulation, resolution of the parenchymal "gro
239 RATION, RANIBIZUMAB EGRESSES SLOWLY INTO THE SYSTEMIC CIRCULATION, RESULTING IN AN APPARENT SERUM T1/
240 nism by which breast cancer cells access the systemic circulation, resulting in distant metastasis an
241  exit bone marrow, losing Gr1, and enter the systemic circulation, seeding the gastrointestinal syste
242   Variations in the fetal umbilical or porto-systemic circulations should be detected by fetal or new
243  list of signals sent by an injured organ to systemic circulation, so-called danger signals, is growi
244                               Studies on the systemic circulation suggest that it may reduce vascular
245 ocate only minimally from the lungs into the systemic circulation, suggesting that extrapulmonary tox
246 istered SCFAs that could be recovered in the systemic circulation, the fraction that was excreted via
247 e number of tumor-specific CD8(+) T cells in systemic circulation, they frequently fail to increase t
248 l molecular weight substances that enter the systemic circulation through resorption in the gastroint
249 he elimination of pathobionts that enter the systemic circulation through the regulation of the compl
250 nslocate across the epithelium and enter the systemic circulation to cause systemic (pathological) ef
251 iting unidirectional influx of iron from the systemic circulation to cerebral compartment.
252  fusions from a depot combined with enhanced systemic circulation to create a tunable peptide deliver
253 ted levels of (conjugated) bile acids in the systemic circulation to induce FGF15/19, which modulates
254 SP-D influenced the response of the lung and systemic circulation to intratracheally administered Esc
255 the ability to deliver therapeutics from the systemic circulation to lesions.
256 ble of specifically delivering genes via the systemic circulation to solid tumors subcutaneously impl
257 s of anesthetic molecules distributed by the systemic circulation to the cerebral cortex (for amnesia
258 ion facilitates the transfer of NGF from the systemic circulation to the CNS via the transferrin tran
259 rmally occurs through a proliferation of the systemic circulation to the intraparenchymal airways.
260 e parameters in a model of the heart and the systemic circulation using exclusively non-invasive meas
261                                       In the systemic circulation, vascular injury is associated with
262 ar, we highlight three areas: (i) prolonging systemic circulation via cell membrane coating, (ii) cel
263 flammatory factors are reaching the lung and systemic circulation via the gut lymphatics rather than
264 nto femoral bone marrow cavities or into the systemic circulation via the left ventricle.
265 arried in the mesenteric lymph and reach the systemic circulation via the mesenteric lymph, thereby u
266 ecovery of 111In-platelets injected into the systemic circulation was 33% +/- 16% (P = .0001 compared
267 of lipopolysaccharides from the lungs to the systemic circulation was prevented by intratracheal reco
268 age of ingested glucose that appeared in the systemic circulation was slightly lower after than befor
269  and smooth muscle cell proliferation in the systemic circulation, we hypothesized that TRAIL is an i
270 ntributed a substantial amount of Tyr to the systemic circulation where the splanchnic bed was a net
271 treated tissue and should not diffuse in the systemic circulation, where it may reach undesired organ
272 tumor-derived VEGF that remain stably in the systemic circulation, where they are readily assayable,
273 f endotoxin and bacterial metabolites to the systemic circulation, which contributes to uremic toxici
274 ducts across the intestinal barrier into the systemic circulation, which induces an inflammatory resp
275 ed from changes in perfusion pressure to the systemic circulation, which was perfused at constant flo
276 e essential nutrients for replication in the systemic circulation, while avoiding exclusion by host i
277        When platelets were depleted from the systemic circulation with an anti-platelet antibody, blo
278 OIR were injected within the vitreous or the systemic circulation with fluorescently labeled CD34(+)
279 pinally produce analgesia by uptake into the systemic circulation with subsequent redistribution to b
280  appearance of administered glucose into the systemic circulation with total parenteral nutrition at
281 y is characterized by parallel pulmonary and systemic circulations, with effective blood flow to each
282 are recruited to the genital mucosa from the systemic circulation without significant selection press

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