ライフサイエンスコーパス: systemic inflammation

1 infection-positive versus infection-negative systemic inflammation.

2 it is highly induced in muscle cells during systemic inflammation.

3 - and probiotic combinations (synbiotics) on systemic inflammation.

4 ar stage lungs of preterm infants exposed to systemic inflammation.

5 mmative risk related to multiple pathways of systemic inflammation.

6 are associated with increases in markers of systemic inflammation.

7 pha, which is consistent with the persistent systemic inflammation.

8 culture and correlated with the intensity of systemic inflammation.

9 sity, reduce skeletal muscle mass, and cause systemic inflammation.

10 porting its potential use as an inhibitor of systemic inflammation.

11 ectly via their more direct association with systemic inflammation.

12 -22 axis impairs PGE2-mediated inhibition of systemic inflammation.

13 hippocampi are low and further reduced after systemic inflammation.

14 ct pathways that are involved in hepatic and systemic inflammation.

15 ease in exercise performance observed during systemic inflammation.

16 RT initiation was associated with heightened systemic inflammation.

17 uce interleukin-6 in middle-aged mice during systemic inflammation.

18 assayed for circulating IL-6, a biomarker of systemic inflammation.

19 ne, respiratory mortality, and biomarkers of systemic inflammation.

20 in sensing pathogens and promoting local and systemic inflammation.

21 d intestinal permeability and intestinal and systemic inflammation.

22 , adventitial fibroblasts, and pulmonary and systemic inflammation.

23 recognition platform that triggers local and systemic inflammation.

24 , in six unrelated families with early-onset systemic inflammation.

25 ammatory and procoagulant genes during acute systemic inflammation.

26 ), develop severe dermatitis associated with systemic inflammation.

27 ning lymph nodes while dramatically reducing systemic inflammation.

28 characterized by IgE responses and local and systemic inflammation.

29 ng myocardial injury, hemodynamic stress, or systemic inflammation.

30 g the effect of prebiotics and synbiotics on systemic inflammation.

31 and FEV1 decline, respiratory mortality, and systemic inflammation.

32 ha7 (nAChRa7) signaling in the regulation of systemic inflammation.

33 ficiencies in immune responses and increased systemic inflammation.

34 Deficiency in mevalonate kinase (MVK) causes systemic inflammation.

35 ated with tissue damage and are hallmarks of systemic inflammation.

36 stress disorder patients experience chronic systemic inflammation.

37 ction, enabling PGE2-EP4 signaling to impede systemic inflammation.

38 deficient mice considerably alleviated their systemic inflammation.

39 , whereas there was no significant change in systemic inflammation.

40 eu5Gc antibodies, they developed evidence of systemic inflammation.

41 fter injection, indicating induction of mild systemic inflammation.

42 l physiologic and behavioral effects of mild systemic inflammation.

43 een neonatal lung function and biomarkers of systemic inflammation.

44 metastatic pancreatic cancer and evidence of systemic inflammation.

45 inflammatory responses and thereby prevents systemic inflammation.

46 in (hsCRP) serum concentration - a marker of systemic inflammation.

47 over and T-helper type 17 cells with minimal systemic inflammation.

48 n have increased microbial translocation and systemic inflammation.

49 a and markers of microbial translocation and systemic inflammation.

50 ainage, fascial closure rates, or markers of systemic inflammation.

51 is affected by age or the presence of acute systemic inflammation.

52 infected neutrophilic RA was associated with systemic inflammation.

53 y distributed to the bloodstream, leading to systemic inflammation.

54 is of neurological disorders following acute systemic inflammation.

55 levels, as well as reductions in airway and systemic inflammation.

56 ght loss, atrophy of adipose tissue (AT) and systemic inflammation.

57 e actions of these statins on both joint and systemic inflammation.

58 ion in the serum, suggesting the presence of systemic inflammation.

59 a life-saving response that occurs in severe systemic inflammation.

60 omplete afferent KES nerve block exacerbates systemic inflammation.

61 which was associated with reduced local and systemic inflammation.

62 (CRP) encoded by CRP gene is a reflection of systemic inflammation.

63 in Apoe (-/-) mice by regulating lesion and systemic inflammation.

64 -GFI-1 pathway preceding vascular damage and systemic inflammation.

65 isk in patients with CKD who exhibit chronic systemic inflammation.

66 ted a significant decrease in >/=1 marker of systemic inflammation.

67 ifically as it relates to neuromodulation of systemic inflammation.

68 n response to virus infection and associated systemic inflammation.

69 Excessive systemic inflammation after abdominal injury or intra-ab

70 Increasing evidence has suggested that systemic inflammation along with local brain inflammatio

71 Systemic inflammation also affects other organs such as

72 esity is characterized by chronic low-grade, systemic inflammation, altered gut microbiota, and gut b

73 s taxa were negatively linked with brain and systemic inflammation, ammonia, and with Staphylococcace

74 eactivity (AHR) on respiratory mortality and systemic inflammation among patients with chronic obstru

75 ion of CLEC-2 but not GPVI leads to enhanced systemic inflammation and accelerated organ injury in tw

76 hormones, oral contraceptive pill (OCP) use, systemic inflammation and airway inflammation in adults

77 entrations of 3-hydroxykynurenine paralleled systemic inflammation and AP severity.

78 n to relate brain microglial activation with systemic inflammation and behavior.

79 racteristics of the human disease, including systemic inflammation and cartilage dysplasia, but the m

80 Altered gut microbiome is associated with systemic inflammation and cirrhosis decompensation.

81 mmation in the pancreas that may progress to systemic inflammation and complications.

82 ntricular remodeling and dysfunction through systemic inflammation and coronary microvascular endothe

83 he sequelae of cancer treatment may increase systemic inflammation and create a phenotype at increase

84 y regulated because it can potentiate lethal systemic inflammation and death.

85 rate distinct roles of SHARPIN in initiating systemic inflammation and dermatitis.

86 ted host response to an infection leading to systemic inflammation and endothelial barrier breakdown.

87 for 10 wk alleviated both adipose tissue and systemic inflammation and enhanced physical function.

88 , during exercise, is mainly associated with systemic inflammation and excessive ventilation for meta

89 neural substrate of cold-seeking behavior in systemic inflammation and expands the functional topogra

90 GVHD-induced ER stress and thereby alleviate systemic inflammation and fibrosis.

91 em cell transplantation and causes disabling systemic inflammation and fibrosis.

92 ation modulator, is a potential link between systemic inflammation and gut immune dysfunction during

93 ls into septic mice significantly attenuated systemic inflammation and improved survival, whereas B-1

94 sceral adiposity is strongly associated with systemic inflammation and increased cardiometabolic risk

95 ine head and neck cancer model (mEER) caused systemic inflammation and increased expression of Il1b i

96 Both pathologies elicit systemic inflammation and induce a robust acute-phase re

97 cently been implicated in the development of systemic inflammation and insulin-resistant diabetes mel

98 Here, scFv/TM was studied in mouse models of systemic inflammation and ischemia-reperfusion injury.

99 ets for intervention to suppress CKD-related systemic inflammation and its consequences.

100 ACLF displays key features of systemic inflammation and its poor outcome is closely as

101 astating metabolic syndrome characterized by systemic inflammation and massive muscle and adipose tis

102 protective factor in the CNS in response to systemic inflammation and may be a potential candidate f

103 Interleukin-6 (IL-6) is a biomarker of systemic inflammation and metabolic dysfunction, and we

104 They are important regulators of local and systemic inflammation and metabolism.

105 lated kinase inhibitor trametinib attenuates systemic inflammation and multiple organ damage in a cli

106 dence points to organ-specific properties of systemic inflammation and NK cells.

107 due to increased osteolysis, but there is no systemic inflammation and no change in osteoclast number

108 SSc pathophysiology involves systemic inflammation and oxidative stress.

109 , poor clinical outcomes correlate both with systemic inflammation and poor proliferative ability of

110 ulating inflammatory cytokines, may link the systemic inflammation and poor T cell function character

111 ittle is known about the association between systemic inflammation and preclinical AD pathophysiology

112 ggesting its role in nonatopic TH1-polarized systemic inflammation and pulmonary function deficits fo

113 Systemic inflammation and sarcopenia are easily evaluate

114 , with promising results in animal models of systemic inflammation and sepsis.

115 These mice exhibit systemic inflammation and severe osteopenia ( approximat

116 Both systemic inflammation and sex hormones have been propose

117 iting neuroinflammation through reduction of systemic inflammation and standardized neuroprotection p

118 on of HP was associated with the severity of systemic inflammation and the development of sepsis.

119 clines or radiation, should be monitored for systemic inflammation and the risk of premature cardiova

120 rtmentalization of NK cells responses during systemic inflammation and to show that NK cell-intrinsic

121 ergence was due to different trajectories of systemic inflammation and utilized computational analyse

122 I/R injury was associated with increased systemic inflammation and weight loss.

123 activity, persistent low-grade pulmonary and systemic inflammation) and add to the overall morbidity

124 Increasing mGPS (systemic inflammation) and deteriorating PS were associa

125 sted an association among sepsis, subsequent systemic inflammation, and adverse cardiovascular outcom

126 al liaisons connecting commensal microbiota, systemic inflammation, and distal tumor growth.

127 yed accentuated insulin resistance, enhanced systemic inflammation, and dramatically increased Nlrp3

128 t the maintenance of the intestinal barrier, systemic inflammation, and glucose metabolism.

129 preeclampsia with vascular damage, enhanced systemic inflammation, and insulin resistance; in the pl

130 use was associated with worse lung function, systemic inflammation, and metabolic health at age 38 ye

131 l health (periodontal health, lung function, systemic inflammation, and metabolic health), as well as

132 ng left ventricular and pulmonary pathology, systemic inflammation, and neurohormonal activation.

133 plex interactions between the immune system, systemic inflammation, and the brain, which can lead to

134 he onset of periodontal tissue breakdown and systemic inflammation, and the success of antiresorptive

135 cted third molars are associated with higher systemic inflammation, and their removal may represent a

136 n vitro and in mouse models of infection and systemic inflammation, and they improved mortality in mu

137 ociated altered metabolic profile, increased systemic inflammation, and, in men, poorer liver functio

138 and permeability); microbial translocation; systemic inflammation; and hormonal determinants of grow

139 tigations of possible effects of attenuating systemic inflammation are now warranted.

140 low concentrations of fecal SCFAs, and high systemic inflammation are significantly related to morta

141 , thereby excluding this marker of low-grade systemic inflammation as a possible explanation for the

142 t, over several months, showed reductions in systemic inflammation as measured by plasma alpha-macrog

143 Systemic inflammation, as seen in obesity, is associated

144 Systemic inflammation associated with brain death (BD) d

145 tand the effects of psoriasis medications on systemic inflammation associated with cardiovascular ris

146 the hallmark salivary gland inflammation and systemic inflammation associated with disease.

147 tic mice had intestinal dysbiosis as well as systemic inflammation, associated with increased serum a

148 Mice with reduced PGE2 synthesis develop systemic inflammation, associated with translocation of

149 Typhoid vaccine induced mild systemic inflammation at 8 hours, reflected by increased

150 aims to examine the evidence for the role of systemic inflammation based prognostic scores in patient

151 cyte ratio (NLR) was used as an indicator of systemic inflammation before and after surgery.

152 myocardial fibrosis, and serum biomarkers of systemic inflammation beyond current guideline-based sta

153 Osteoprotegerin is a marker of vascular and systemic inflammation but has not been investigated in r

154 CKD associates with systemic inflammation, but the underlying cause is unkno

155 ions: metabolic risk by caloric restriction, systemic inflammation by statins, pulmonary hypertension

156 In severe trauma, overwhelming systemic inflammation can result in additional damage an

157 Stresses like low nutrients, systemic inflammation, cancer or infections provoke a ca

158 Systemic inflammation caused a decrease in FMD in males,

159 ase 1 knockout (Trex1(-/-)) mice suffer from systemic inflammation caused largely by chronic activati

160 Systemic inflammation causes malaise and general feeling

161 lopathy with onset in infancy (SAVI) develop systemic inflammation characterized by vasculopathy, int

162 Systemic inflammation commonly results from dysregulated

163 estic and selected amnestic tests, HRQOL and systemic inflammation compared to non-cirrhotics.

164 vans Blue dye extravasation, suggesting that systemic inflammation contributes to TBI-triggered BBB p

165 genes in myeloid cells dampen virus-induced systemic inflammation, creating an environment that fost

166 ate that VNS-mediated attenuation of AKI and systemic inflammation depends on alpha7nAChR-positive sp

167 iation between number of teeth and low-grade systemic inflammation deserves consideration within the

168 ore features of the SAVI phenotype including systemic inflammation, destructive skin lesions, and int

169 ortantly, Toll-like receptor (TLR)-dependent systemic inflammation during 2,6,10,14-tetramethylpentad

170 Preeclampsia reflects an unusual increase in systemic inflammation during pregnancy.

171 to pathogen dissemination and intestinal and systemic inflammation during the oral route of infection

172 a significantly worse cognitive performance, systemic inflammation, dysbiosis and hyperammonemia comp

173 Sepsis is characterized by systemic inflammation, edema formation and hypo-perfusio

174 deterioration had significantly worse shock, systemic inflammation (elevated tumor necrosis factor-al

175 As a consequence of infection, systemic inflammation emerges and is directly related to

176 rtic stiffening and provide insight into the systemic inflammation encountered in common vascular dis

177 extent to which adult lifestyle factors and systemic inflammation explain this relationship.

178 (HFCS), and glucose differentially influence systemic inflammation [fasting plasma C-reactive protein

179 All four had marked systemic inflammation, fever and fluctuating radiologic

180 Obesity was associated with systemic inflammation, greater leg fat mass, and pattern

181 that would (1) determine which patients with systemic inflammation had sepsis, (2) be robust across i

182 Systemic inflammation has been proposed as a physiologic

183 Links between microbial alterations and systemic inflammation have been demonstrated in chronic

184 PM2.5-induced endothelial dysfunction and systemic inflammation have been implicated, but direct e

185 play an important role in the regulation of systemic inflammation; however, the functional role of t

186 ognosis of patients with cancer cachexia and systemic inflammation (i.e., those with a mGPS of 1 or 2

187 Systemic inflammation impairs brain function and is incr

188 ic antiinflammatory pathway (CAP) attenuates systemic inflammation, improving survival in animal seps

189 ts resulting in immune activation and drives systemic inflammation in acquired immunodeficiency syndr

190 There is growing evidence for the role of systemic inflammation in Alzheimer's disease (AD) and ot

191 esultant lower CD4/CD8 ratios, and increased systemic inflammation in ART-treated HIV infection.

192 association between hypertension and chronic systemic inflammation in both human hypertension and exp

193 association between hypertension and chronic systemic inflammation in both human hypertension and exp

194 To test for causation between dysbiosis and systemic inflammation in CKD, we eradicated facultative

195 ation, which trigger the state of persistent systemic inflammation in CKD.

196 tty acids (PUFAs) is associated with chronic systemic inflammation in healthy, free-living individual

197 d support to a hypothesis implicating global systemic inflammation in HF with preserved ejection frac

198 Chronic systemic inflammation in HIV, which involves the myocard

199 w here that ethylene is also produced during systemic inflammation in humans and is released in exhal

200 N is essential for preventing TNF-associated systemic inflammation in humans and mice.

201 Systemic inflammation in humans may be triggered by infe

202 nously, or per rectum; were on biomarkers of systemic inflammation in humans; and performed meta-anal

203 that plasmodial DNA is the primary driver of systemic inflammation in malaria, both within the phagol

204 not differentially affect low-grade chronic systemic inflammation in normal-weight to obese adults.

205 We inhibited systemic inflammation in old subjects by means of pretre

206 oved FMDBA without changing aPWV and reduced systemic inflammation in patients with CKD.

207 e describe the prevailing characteristics of systemic inflammation in patients with decompensated cir

208 ociated with reductions in intra-adipose and systemic inflammation in the high fat-fed state, enhance

209 CKD-related systemic inflammation in these mice associated with inte

210 ggest that t2DM may be the primary driver of systemic inflammation in these patients.

211 hritis model and in IL-1beta- or LPS-induced systemic inflammation in vivo, IL-1R2(-/-) mice were cre

212 evidence supports the active involvement of systemic inflammation, in addition to local brain inflam

213 t syndrome-related progressive CKD displayed systemic inflammation, including increased plasma levels

214 chronic MHV68 infection triggered increased systemic inflammation, increased T cell production of IF

215 It has been suggested that systemic inflammation increases the risk of age-related

216 These results indicate that systemic inflammation induced by LPS administration caus

217 ovides novel information on host response to systemic inflammation induced by periodontal pathogens t

218 Using a rat model of "systemic inflammation-induced cardiac dysfunction" induc

219 ngs suggest that female sex protects against systemic inflammation-induced endothelial dysfunction.

220 rols (n = 50), we measured parasite biomass, systemic inflammation (interleukin 6 [IL-6]), endothelia

221 Systemic inflammation is a hallmark of commonly encounte

222 Systemic inflammation is a whole body reaction having an

223 Systemic inflammation is also found in patients with COP

224 Systemic inflammation is increased in patients who devel

225 risk of AMD, supporting the possibility that systemic inflammation is involved in the pathogenesis of

226 Although systemic inflammation is linked to cardiovascular risk,

227 However, the origin of age-associated systemic inflammation is unknown.

228 s a primary gut disorder that drives chronic systemic inflammation, leading to growth hormone resista

229 TLR4 activation promotes local and systemic inflammation, leading to induction of multiple

230 nt paradox of reduced IL-1beta secretion but systemic inflammation led to the hypothesis that CASP1 m

231 TLR9)-mediated sensing significantly reduced systemic inflammation, liver neutrophil recruitment, and

232 In addition to systemic inflammation, local arterial inflammation, driv

233 viduals on ART is predicted by biomarkers of systemic inflammation, many of which are implicated in m

234 ation cohort, we observed differences in the systemic inflammation marker, neutrophil to lymphocyte r

235 This study suggests that sex hormones and systemic inflammation may be mediating the obese-asthma

236 have shown that both airflow obstruction and systemic inflammation may contribute to endothelial dysf

237 ammatory cells into the muscle but to little systemic inflammation measured by serum cytokine levels.

238 Neither age nor the presence of acute systemic inflammation modified this relationship.

239 terleukin-8 in a synergistic manner inducing systemic inflammation, neutrophil exhaustion, and exacer

240 damage of endothelial cells and promote the systemic inflammation observed in this disease.

241 patients with recurrent febrile episodes and systemic inflammation of unknown origin harbor mutations

242 f the innate immune system, characterized by systemic inflammation often driven by inflammasomes, and

243 ndividual contribution of hyperammonemia and systemic inflammation on neuroinflammation in cirrhosis

244 nd reduced skeletal muscle mass, but not the systemic inflammation or increased adipose tissue macrop

245 rongest changes between patients with either systemic inflammation or sepsis in gene expression of th

246 was associated with low levels of local and systemic inflammation, oxidative cellular stress, cell i

247 molar extraction exhibited greater levels of systemic inflammation, oxidative stress, and triglycerid

248 Systemic inflammation participates to the complex healin

249 Mortality was directly related to high systemic inflammation (path coefficient = 0.49), whereas

250 Systemic inflammation perturbs the bone marrow environme

251 gration through the venous wall during acute systemic inflammation, placing Panx1 channels at the cen

252 ecent findings suggest that an overexuberant systemic inflammation plays a primary role in ACLF progr

253 A critical cause of NASH is chronic systemic inflammation promoted by innate immune cells, s

254 Systemic inflammation promotes cardiovascular disease.

255 , and macrophages, participates in the acute systemic inflammation provoked by LPS.

256 st-surgical patients with infection-negative systemic inflammation) recruited at five tertiary care s

257 Systemic inflammation responses have been associated wit

258 on, cancer, or other conditions that trigger systemic inflammation responses.

259 ve clinical utility for differentiating host systemic inflammation (SI) due to viral versus bacterial

260 Recently, we have proposed (systemic inflammation [SI] hypothesis) that ACLF is the

261 the colon and reduces colon inflammation and systemic inflammation, similarly to PEA.

262 e macrophage HIF-1alpha-PDK1 axis suppresses systemic inflammation, suggesting a potential therapeuti

263 hmatic children have nonatopic TH1-polarized systemic inflammation that correlates with pulmonary fun

264 Since sepsis is the most severe form of systemic inflammation, the primary objective was to eval

265 on in the early phase after fracture reduced systemic inflammation, the recruitment of immune cells,

266 enhanced leukocyte recruitment reflective of systemic inflammation thought to precede and underlie at

267 d HE are unclear although hyperammonemia and systemic inflammation through gut dysbiosis have been pr

268 HE) are unclear, although hyperammonemia and systemic inflammation through gut dysbiosis have been pr

269 Systemic inflammation through persistent monocyte activa

270 ed carbon nanotubes (MWCNTs) causes indirect systemic inflammation through unknown pathways.

271 AKI associates with intrarenal and systemic inflammation; thus, improved understanding of t

272 rate that deregulated necroptosis results in systemic inflammation, tissue fibrosis, and autoimmunity

273 erein, we used a well-characterized model of systemic inflammation to determine the mechanisms allowi

274 some detail, the contribution of peripheral/systemic inflammation to TBI pathophysiology is largely

275 in levels, and fully reversed all markers of systemic inflammation to the level of nonuremic controls

276 armacology, and chemogenetics, we found that systemic inflammation triggered aversion through MyD88-d

277 ges, and dendritic cells protected mice from systemic inflammation triggered by molecular PAMPs, infl

278 6 production in this depot and the low-grade systemic inflammation typically associated with visceral

279 Host genes that regulate systemic inflammation upon chronic viral infection are i

280 evaluate 1) the differences in biomarkers of systemic inflammation, vascular function, and metabolism

281 Systemic inflammation was assessed by using the modified

282 Increasing systemic inflammation was associated with deterioration

283 Systemic inflammation was associated with quality-of-lif

284 d prior to Il1b detection in the brain, when systemic inflammation was minimal.

285 tumor infiltration of these immune cells, a systemic inflammation was not detected.

286 by using a mouse model of endotoxin-induced systemic inflammation, we show that these inhibitors hav

287 ology Group performance status score 1 or 2, systemic inflammation, weight loss, and other disease-re

288 es, lipids, glucose profiles, and markers of systemic inflammation were significantly reduced in the

289 they improved mortality in murine models of systemic inflammation, which are associated with NET-ind

290 We considered the possibility that systemic inflammation, which arises in subgroups of obes

291 levels of CRP, reflecting diminished chronic systemic inflammation, which in our study was mainly dri

292 resonance spectroscopy-measured biomarker of systemic inflammation, which is associated with the deve

293 el of endometriosis, IL-33 injections caused systemic inflammation, which manifested as an increase i

294 Systemic inflammation, which results from the massive re

295 rapeutic perspectives for COPD patients with systemic inflammation who are unresponsive to rehabilita

296 unological disorder that is characterized by systemic inflammation, widespread organ damage, and hype

297 To examine associations of prediagnostic systemic inflammation with at-diagnosis sarcopenia, and

298 We statistically link early systemic inflammation with later local increases in infl

299 2/CCR2 signaling plays a key role in linking systemic inflammation with seizure susceptibility.

300 ses, characterized by barrier disruption and systemic inflammation, with unique epidermal signatures