ライフサイエンスコーパス: termination factor

1 3, a 3'-end RNA-processing and transcription termination factor.

2 form of Sup35p, a subunit of the translation termination factor.

3 mary site of action is the rho transcription termination factor.

4 of the Saccharomyces cerevisiae translation termination factor.

5 cled in the presence of the La transcription termination factor.

6 he prion form of the yeast Sup35 translation termination factor.

7 ltered conformation of the Sup35 translation termination factor.

8 olymerase, and the rho gene, which encodes a termination factor.

9 in the prion domain of Sup35, a translation-termination factor.

10 mpeting for RNA binding with polyadenylation/termination factors.

11 on factors or with translation elongation or termination factors.

12 n exchange of elongation and polyadenylation/termination factors.

13 ue in the GGQ motif of ribosomal translation termination factors.

14 ng factors, 3'-end-processing complexes, and termination factors.

15 n Tyr1 and both transcription initiation and termination factors.

16 ides underlying the binding of transcription termination factors.

17 yces cerevisiae and that Gle1 interacts with termination factors.

18 elements and mRNA elongation, processing and termination factors.

19 inity binding of mitochondrial transcription termination factor 1 (mTERF1) to the site.

20 ochondria is the mitochondrial transcription termination factor 1 (MTERF1, also denoted mTERF), which

21 -29% identical to mouse TTF-1 (transcription termination factor-1) and Saccharomyces cerevisiae REB1

22 hibit termination of Pol II by transcription termination factor 2 (TTF2) as well as block elongation

23 latory proteins, such as TTF2 (transcription termination factor 2), TFIIS, and RPB9.

24 mined the structure of the Rho transcription termination factor, a hexameric RNA/DNA helicase, with s

25 The transcription termination factor activity of the D1-D12 capping enzyme

26 nitiation factor activity of La augments its termination factor activity to produce a novel mechanism

27 Evidence indicates that a required termination factor acts through binding to the UUUUUNU s

28 Finally, termination factors also contribute to genomic stability

29 at a stalled RNAP in the absence of vaccinia termination factor and U(5)NU when transcription elongat

30 codon nucleotide context, the activities of termination factors and the abundance of suppressor tRNA

31 cessing or translation, and (iii) recruiting termination factors and thereby silencing laterally tran

32 NELF interacts with Pcf11, a transcription termination factor, and diminishing Pcf11 in primary CD4

33 TP-dependent RNA polymerase II transcription termination factor, and discovered that it was identical

34 up35 protein is a subunit of the translation termination factor, and its conversion to the [PSI (+)]

35 osomal subunits; initiation, elongation, and termination factors; and aminoacyl tRNAs.

36 mination site by mitochondrial transcription termination factor (approximately 80%).

37 lso a subunit of the essential transcription termination factor APT (associated with Pta1).

38 Using the Escherichia coli Rho transcription termination factor as a model system, we have used solut

39 e structure of the E. coli Rho transcription termination factor bound to RNA and nucleotide.

40 otein, normally a subunit of the translation termination factor, but impaired in this vital function

41 rpedo model in which Rat1 is not a dedicated termination factor, but is an integrated component of th

42 rmination activity (Eta), the first archaeal termination factor capable of disrupting the transcripti

43 Vaccinia termination factor/capping enzyme is a multifunctional h

44 rase requires a termination factor (vaccinia termination factor/capping enzyme) and is coupled to the

45 ies are shared by the homologous translation termination factor complex eRF1:eRF3, suggesting a commo

46 We demonstrate that negative and positive termination factors control the efficiency of terminatio

47 bacterial morphogenesis, but polymerization termination factors controlling this process have yet to

48 endent ATPase that serves as a transcription termination factor during viral mRNA synthesis.

49 interaction of transcription initiation and termination factors during gene looping in budding yeast

50 Thus, the action of a eukaryotic termination factor entails recognition of the nucleotide

51 have shown that domain 1 of the translation termination factor eRF1 mediates stop codon recognition.

52 Downregulating the translation termination factor eRF1 produces defective virus particl

53 lates Gln(185) of the eukaryotic translation termination factor eRF1.

54 s have proposed a direct role for eukaryotic termination factors eRF1 and eRF3 (and the related facto

55 34p and Hbs1p are similar to the translation termination factors eRF1 and eRF3, indicating that these

56 ed that Tpa1p interacts with the translation termination factors eRF1 and eRF3.

57 1p interact with both eukaryotic translation termination factors eRF1 and eRF3.

58 and self-propagating form of the translation termination factor eRF3 (Sup35), can be cured of its inf

59 Translation termination factor eRF3 enhances the activity of release

60 prion state of the S. cerevisiae translation termination factor eRF3, Rps23p hydroxylation can either

61 is caused by a prion form of the translation termination factor eRF3.

62 n elongation factor EF1A and the translation termination factor eRF3.

63 the second requires an 80S ribosome and the termination factors eRF3/Sup35 and eRF1/Sup45.

64 (Leu(UUR)) gene that binds the transcription termination factor failed to reveal any difference in oc

65 tion in the Sen1 helicase, which is a Pol II termination factor for noncoding RNA genes.

66 Addition of rho termination factor from E. coli induces RNA pol II to re

67 itination and degradation of the translation termination factor GSPT1.

68 inase 1alpha (CK1alpha), and the translation termination factor GSPT1] whose ubiquitylation is induce

69 tmRNA(+) and DeltatmRNA cells, whereas other termination factors had little or no effect on recycling

70 racterized in each domain, but transcription termination factors have been identified only in bacteri

71 Although many eukaryotic termination factors have been identified to date, the de

72 Two termination factors have been identified.

73 binder of ARL 2, Paxillin, and transcription termination factor I have not been previously reported t

74 A genetic screen to identify termination factors identified an allele that separated

75 el antibiotic that targets rho transcription termination factor in Escherichia coli.

76 present the first example of a transcription termination factor in Saccharomyces cerevisiae that affe

77 results suggest that the mechanisms used by termination factors in archaea, eukarya, and bacteria to

78 human TTF2, an RNA polymerase (Pol) I and II termination factor, in mitotic repression of transcripti

79 Two pathways of transcription termination, factor-independent and -dependent, exist in

80 To our knowledge, intended aggregation of a termination factor is a way to overcome the bacterial tr

81 Rho termination factor is an essential hexameric helicase re

82 consistent with a model in which a required termination factor is converted from an inactive to an a

83 The involvement of the termination factors is independent of a termination even

84 se that a critical function of transcription termination factors is to prevent TEC from blocking DNA

85 When Sup35, a yeast translation termination factor, is aggregated in its [PSI(+)] prion

86 reducing expression levels of the viral anti-termination factor M2-1.

87 is devoid of the mitochondrial transcription termination factor MOC1 and aberrantly expresses the mit

88 The human mitochondrial transcription termination factor mTERF plays a central role in the con

89 The human mitochondrial transcription termination factor (mTERF) cDNA has been cloned and expr

90 of the so-called mitochondrial transcription termination factor (mTERF) family are found in metazoans

91 a member of the mitochondrial transcription termination factor (MTERF) family of proteins, MTERF4, r

92 The human mitochondrial transcription termination factor (mTERF) is a nuclear-encoded 39-kDa p

93 The mitochondrial transcription termination factor (mTERF) proteins are nucleic acid bin

94 -4 1), encodes a mitochondrial transcription termination factor (mTERF)-related protein, one of 35 Ar

95 tch of the human mitochondrial transcription termination factor MTERF1, which has a modular, superhel

96 Rho transcription termination factor mutant, F355W, showed tryptophan fluo

97 -binding dynamics of the yeast transcription termination factor Nab3 in response to glucose starvatio

98 w that it is the translation initiation (not termination) factor, namely eIF3, which critically promo

99 ignal (UUUUUNU) in the nascent RNA, vaccinia termination factor, nucleoside triphosphate phosphohydro

100 titermination, was restored by the bacterial termination factor NusA.

101 , but still responsive to, the transcription termination factor NusG.

102 Our data reveal that WNK1 phosphorylates the termination factor PCF11 on its RNA polymerase II (Pol I

103 We show that the termination factor, Pcf11, causes premature termination

104 a56 mutant allele by impeding recruitment of termination factors Pcf11p and Rna15p (subunits of cleav

105 Notably, termination factors play an additional promoter role by

106 We also show that, like Mfd, the Rho termination factor promotes forward translocation of RNA

107 a protein related to the yeast transcription termination factor Rai1, is essential for piRNA producti

108 fic DNA bound proteins such as the RNA pol I termination factor, Reb1p, or lac repressor.

109 ity control (post PT QC) mechanism where the termination factors recognize mismatched (i.e. error-con

110 (2) A general transcription termination factor, recruited by transcribing Pol II at

111 homohexameric Escherichia coli transcription termination factor Rho along RNA, rates for association

112 hat a major function of the Escherichia coli termination factor Rho and its cofactor, NusG, is suppre

113 The expression and activity of transcription termination factor Rho and the requirement for transcrip

114 The transcription termination factor Rho associates with most nascent bact

115 However, the termination factor Rho can remove the nonantiterminated

116 mutations in Escherichia coli transcription termination factor Rho enhance in vitro transcription te

117 Escherichia coli transcription termination factor Rho exhibits the phenomenon of cataly

118 The active form of transcription termination factor rho from Escherichia coli is a homohe

119 Transcription termination factor Rho from Escherichia coli is a protei

120 The function of transcription termination factor Rho from Escherichia coli is dependen

121 Transcription termination factor Rho from Micrococcus luteus, a high G

122 The gene which encodes transcription termination factor Rho from Rhodobacter sphaeroides 2.4.

123 se activity of Escherichia colitranscription termination factor rho have been analyzed.

124 vities of the Escherichia coli transcription termination factor rho have been investigated using natu

125 ons M219K, S266A, and G337S in transcription termination factor Rho have been shown to confer resista

126 k, we describe the role of the transcription termination factor Rho in prophage maintenance through c

127 The transcription termination factor Rho is a global regulator of RNA poly

128 Escherichia coli transcription termination factor rho is a hexamer with three catalytic

129 Escherichia coli transcription termination factor Rho is a ring-shaped hexameric protei

130 Transcription termination factor Rho is also likely not involved, beca

131 The Escherichia coli transcription termination factor Rho is structurally and functionally

132 Inhibition of the transcription termination factor Rho is used to treat some bacterial i

133 pe and mutant Escherichia coli transcription termination factor Rho provides a model for the enzyme-R

134 Escherichia coli transcription termination factor Rho shows a 30-fold faster rate of AT

135 scherichia coli genome require transcription termination factor rho to function.

136 Escherichia coli transcription termination factor Rho uses the energy of ATP hydrolysis

137 the essential Escherichia coli transcription termination factor rho utilizes Mg(2+) and ATP as a subs

138 HEH domains from the bacterial transcription termination factor Rho, bacterial and eukaryotic lysyl-t

139 roles in the Escherichia coli transcription termination factor Rho, E211, R366, R212, and D265, and

140 Mutants in Escherichia coli transcription termination factor Rho, termed rho(nusD), were previousl

141 mutations in rho, the gene for transcription termination factor Rho, that block the growth of phages

142 he transcription elongation Nus proteins and termination factor Rho, which are involved in rRNA antit

143 tural product inhibitor of the transcription termination factor rho.

144 script containing RNA residues recognized by termination factor Rho.

145 ion in Escherichia coli is the transcription termination factor rho.

146 ion in Escherichia coli is the transcription termination factor rho.

147 the activity of the M. luteus transcription termination factor Rho.

148 plary homohexameric motor, the transcription termination factor Rho.

149 either in the RNA polymerase complex or the termination factor rho.

150 CM), a potent inhibitor of the transcription termination factor Rho.

151 A transcription termination factor (Rho) was purified from the Gram-posi

152 hape-determining protein (mreB), and the rho termination factor (rho).

153 les: initiation factors, elongation factors, termination factors, ribosomes, mRNA, amino-acylsyntheta

154 , which are subsequently disassembled by the termination factor Rli1, an ATPase.

155 Ser5-P while that bound to the transcription termination factor Rtt103 had higher levels of Ser2-P.

156 the human homolog of the yeast transcription termination factor Rtt103, remain undefined.

157 Also, depletion of termination factors substantially reduces Pol II pausing

158 on [PSI(+)], a prion form of the translation termination factor Sup35 (eRF3).

159 When the translation termination factor Sup35 adopts the prion state, [PSI(+)

160 roteins are, respectively, the translational termination factor Sup35 and the yet poorly characterize

161 Pin3) promotes conversion of the translation termination factor Sup35 into its prion form, [PSI(+)].

162 rom the prion domain NM of yeast translation termination factor Sup35 persistently propagate and inva

163 rains, weak and strong, of yeast translation termination factor Sup35 with respect to angular orienta

164 prion [PSI(+)] (prion form of translational termination factor Sup35).

165 t prion [PSI (+)], formed by the translation termination factor Sup35.

166 uating amyloid conformers of the translation termination factor Sup35.

167 self-perpetuating isoform of the translation termination factor Sup35.

168 SI(+)] is a prion isoform of the translation termination factor Sup35.

169 lf-perpetuating amyloid of the translational termination factor Sup35.

170 ing amyloidogenic isoform of the translation termination factor Sup35.

171 as a mimic of a normal 3'-UTR, recruits the termination factor Sup35p (eRF3) and stabilizes nonsense

172 The prion [PSI+] forms when the translation termination factor Sup35p adopts a self-propagating conf

173 hange in the conformation of the translation termination factor Sup35p is the basis for the prion [PS

174 tional, ordered aggregate of the translation termination factor Sup35p that influences new Sup35 prot

175 conformation and function of the translation termination factor Sup35p, and is transmitted from mothe

176 (+)] is a prion of the essential translation termination factor Sup35p.

177 self-propagating amyloid of the translation termination factor, Sup35p, of Saccharomyces cerevisiae.

178 The Escherichia coli rho transcription termination factor terminates select transcripts and rho

179 La RNA-binding protein is a transcription termination factor that facilitates recycling of templat

180 results, we suggest Grs1p is a transcription termination factor that may interact with the 3'-end of

181 tify many core spliceosome and transcription termination factors that control the RNA outputs of repo

182 The active termination factor then interacts with the ternary compl

183 Although Rho was the first termination factor to be discovered, the actual mechanis

184 differences in the abundance or activity of termination factors to modulate the balance of terminati

185 case DDX5 and RNA polymerase I transcription termination factor (TTF-I), it has been speculated that

186 pping proteins Edc3, Dcp1a, and Dcp2 and the termination factor TTF2 coimmunoprecipitate with Xrn2, t

187 gnal to the elongating polymerase requires a termination factor (vaccinia termination factor/capping

188 e of the nascent RNA depends on the vaccinia termination factor (VTF) and an ATP cofactor.

189 nscription termination requires the vaccinia termination factor (VTF), NPH I, a single stranded DNA-d

190 ing polymerase requires a trans-acting viral termination factor (VTF/capping enzyme), and is coupled

191 ongating polymerase requires a virus-encoded termination factor, VTF.

192 The existence of a second termination factor was suggested by the finding that tra

193 Suppression was efficient when the termination factors were present at physiological levels

194 sult of aggregation of the Sup35 translation termination factor, which increases stop codon read-thro

195 e yeast prion protein Sup35 is a translation termination factor, whose activity is modulated by seque

196 of paused pol II, knockdown of decapping or termination factors Xrn2 and TTF2 shifted polymerase awa