ライフサイエンスコーパス: yeast

1 oteins associated with the GAL1-10 region in yeast.

2 sayed, 20 genes exhibited strong toxicity in yeast.

3 lization and thus phospholipid metabolism in yeast.

4 per splicing of certain pre-mRNAs in fission yeast.

5 e mitochondrial cysteine desulfurase Nfs1 in yeast.

6 ensively studied before those in mammals and yeast.

7 mitotic entry to membrane growth in budding yeast.

8 striction of the contractile ring in fission yeast.

9 igated how heat stress promotes longevity in yeast.

10 the transcriptome in the meiosis of fission yeast.

11 nal well-characterized NLSs from mammals and yeast.

12 eases in mammals and inherited phenotypes in yeast.

13 enhancing promoter directionality in budding yeast.

14 , which is even fewer than that reported for yeast.

15 work in parallel to promote Cse4 turnover in yeast.

16 were identified, confirming the work done in yeast.

17 he abundance of mRNA and reporter protein in yeast.

18 ues at 5' ends of genes that is conserved in yeast.

19 y, most show evidence for divergence in both yeasts.

20 ase maintains chromosome ends from humans to yeasts.

21 s are both frequently found in Saccharomyces yeasts.

22 While the protein composition of various yeast 60S ribosomal subunit assembly intermediates has b

23 ression output, we have conducted in budding yeast a large-scale measurement of the activity of thous

24 The fission yeast actin cytoskeleton is an ideal, simplified system

25 N(tz)AD(+) and N(tz)ADH to be substrates for yeast alcohol dehydrogenase and lactate dehydrogenase, r

26 ng programs have been extensively studied in yeast and animal systems, but much less is known about t

27 eins that support copper-dependent growth in yeast and enhance copper accumulation in Ctr1(-/-) mouse

28 acteroidetes, suggesting that utilization of yeast and fungal cell wall 1,6-beta-glucans is a widespr

29 Consistently, complexes exist in yeast and human cells, but not in bacteria, and correlat

30 be applied to identify sulfated proteins in yeast and human proteome microarrays, and we expect such

31 ly doubles the number of proteins within the yeast and human proteomes that can be explored as potent

32 e the enzymatic activities and structures of yeast and human U6 RNA processing enzyme Usb1, reconstit

33 yze four independently constructed IINs from yeast and humans and find a conserved structure of these

34 In yeast and humans, CCR4 can interact with CAF1 via its N-

35 ast, herein we analyze Hi-C data for budding yeast and identify 200-kb scale TADs, whose boundaries a

36 and the lagging DNA strands were reported in yeast and in human cancers, but the causes of these diff

37 ndocytic adaptors, including Syp1 in budding yeast and its mammalian orthologue, FCHo1.

38 w that over 30% of the effectors localize to yeast and mammalian cell membranes, including a subset o

39 or directly engineering the surfaces of live yeast and mammalian cells through cell surface-initiated

40 Structural analyses of yeast and mammalian CTD are hampered by their repetitive

41 The proposal is based on research on yeast and mammalian muscle and brain that demonstrates t

42 performed comparative ribosome profiling in yeast and mice with various ribonucleases including I, A

43 d CARC sequences blocked TBSV replication in yeast and plant cells.

44 ntrast to the larger Lys and Arg residues in yeast and plant orthologs.

45 XND1 also transactivated gene expression in yeast and plants.

46 with this prediction, protein aggregation in yeast and worms was observed to increase when translatio

47 d recall on three eukaryotic species: human, yeast, and fly.

48 iotic stresses in E. pusillum and transgenic yeast, and its stress-resistant ability was stronger tha

49 However, unlike in prokaryotes, yeasts, and plants, the molecular players involved in Pi

50 amily, Pry1, -2, and -3 (pathogen related in yeast), are encoded in the Saccharomyces cerevisiae geno

51 Using yeast as a model host, we find that one of these protein

52 The interaction pattern of budding yeast as measured from genome-wide 3C studies are largel

53 The virus derived from this yeast-assembled genome, KOS(YA), replicated with kinetic

54 illations of the anaphase spindle in budding yeast, but in A. gossypii, this system is not restricted

55 e systematically replaced essential genes in yeast by their 1:1 orthologs from Escherichia coli.

56 e results define direct structural roles for yeast CAF-1 subunits and uncover a previously unknown cr

57 volved in the direct interaction between the yeast CAF-1 subunits, and mapped the CAF-1 domains respo

58 Studies in yeast can help to illuminate approaches and mechanisms t

59 ability, speed and robustness of the fission yeast cell cycle oscillations.

60 mimetic FUS reduces aggregation in human and yeast cell models, and can ameliorate FUS-associated cyt

61 ngation-can be recapitulated in vitro with a yeast cell-free system.

62 l tubes had increased adhesion compared with yeast cells ( P < 0.05).

63 Fast growing yeast cells are predicted to perform significant amount

64 ed for oxidative stress responses in fission yeast cells by promoting transcription initiation.

65 Here, we show that fission yeast cells carrying a mutation in the DNA-binding prote

66 We show that RNase H2-deficient yeast cells displayed elevated frequency of Rad52 foci,

67 Inhibition of Hsp104 function in yeast cells leads to a failure to generate new propagons

68 show that upon growth at higher temperature, yeast cells relax the retention of DNA circles, which ac

69 Nitrogen replenishment of nitrogen-starved yeast cells resulted in substantial transcriptome change

70 (GET) pathway was described in mammalian and yeast cells that serve as a blueprint of TA protein inse

71 the maximum accumulation of both ions in the yeast cells was observed.

72 Third, treatment of wild-type yeast cells with E9591 or LMT generated cellular defects

73 gnificant regulatory variation in individual yeast cells, both before and after stress.

74 and formation of a shmoo-like morphology in yeast cells, lower pheromone doses elicit elongated cell

75 In dividing yeast cells, protein aggregates that form under stress o

76 ies of formaldehyde-cross-linking in budding yeast cells.

77 rion fusions to encode synthetic memories in yeast cells.

78 anslational modification found in animal and yeast cells.

79 In budding yeast, centromere establishment begins with the recognit

80 tion, we determined the crystal structure of yeast ChaC2 homologue, GCG1, at 1.34 A resolution, which

81 A recent cryoEM structure of yeast CMG shows that duplex DNA enters the helicase and

82 er transport, its heterologous expression in yeast complemented copper-specific defects observed upon

83 The fission yeast contractile ring has been proposed to assemble by

84 f a central beta-turn resembling that of its yeast counterpart.

85 vulnerable to infection by the encapsulated yeast Cryptococcus neoformans Most commonly found in the

86 In fission yeast, cytokinesis involves the type II myosins Myo2p an

87 ontractile ring assembly in vivo.The fission yeast cytokinetic ring assembles by Search-Capture-Pull-

88 se1sbd successfully heterodimerized with the yeast cytosolic Hsp70s Ssa and Ssb and promoted normal g

89 ADP inhibition of human and yeast cytosolic Hsp90 can be relieved by the cochaperone

90 In particular, budding yeast daughter cells are more vulnerable to stresses tha

91 Ms), spread in the long C-terminal region of yeast Dcp2 decapping enzyme.

92 1 R585Q and E152K to rescue the phenotype of yeast deficient in Vms1, the yeast homologue of ANKZF1.

93 Of note, the earliest known Doa10 yeast degron, Deg1, also contains an amphipathic helix a

94 genes into a pool of 4653 homozygous diploid yeast deletion mutants with unique barcode sequences, fo

95 somes are positioned according to endogenous yeast DNA sequence and chromatin-remodeling network, as

96 In yeast, dNTP pools expand drastically during DNA damage r

97 Furthermore, when comparing the DFE across yeast, Drosophila, mice, and humans, the average selecti

98 The spindle pole body (SPB) of budding yeast duplicates once per cell cycle.

99 Here we show that restricting dietary yeast during Drosophila development can, depending upon

100 s, and seven UM-associated substitutions, in yeast eIF1A suppresses initiation at near-cognate UUG co

101 nylalanine amino acid in a reaction with the yeast enzyme of phenylalanine ammonia lyase (PAL).

102 ent structures with requirements that mirror yeast epigenetic gene silencing in vivo.

103 Yeast expressing an Rga2 mutant that is defective for re

104 aegypti and its successful transposition in yeast facilitated the characterization of key steps in M

105 study, we describe data indicating that the yeast family members Ltc1 and Ltc3/4 function at the vac

106 , this regulation is particularly crucial in yeast for the stress-induced transient elevation of PI3,

107 ion effect is made possible by the choice of yeast frataxin, a protein that undergoes cold denaturati

108 Surprisingly, genetic screening reveals that yeast FTase can modify sequences longer than the canonic

109 ammalian MLH1-PMS2 heterodimer; MLH1-PMS1 in yeast) functions in early steps of mismatch repair as a

110 highly conserved Rho-GTPase Cdc42p promotes yeast fusion through interaction with Fus2p, a pheromone

111 Human-yeast genetic interactions were identified by en masse t

112 Thus, SATAY allows to easily explore the yeast genome at unprecedented resolution and throughput.

113 cestral genomes for two high-resolution real yeast genome datasets.

114 imulations of Mig1 configuration within a 3D yeast genome model combined with a promoter-specific, fl

115 H3K4me3 and H3K36me3 patterns throughout the yeast genome.

116 n of Pol II is achieved at most genes in the yeast genome.

117 Today, yeast genomes have been very informative about basic mec

118 ization studies of PSGs with proteins of the yeast GFP collection, mass spectrometry, and direct stoc

119 MoGlo3 partially complements the function of yeast Glo3p.

120 In yeast, glucose activates protein kinase A (PKA) to accel

121 loci prove essential to accurately modeling yeast growth in response to different environments.

122 We discovered that yeast has a recycling route from endosomes to the cell s

123 For example, yeast have been reported to detect pheromone gradients a

124 In addition to ethanol, yeasts have the potential to produce many other industri

125 other in vitro, and at least in the fission yeast, heterologous Oxs1 and Pap1-homologues can substit

126 udies, while their Saccharomyces cerevisiae (yeast) homologs are stable components of U1 snRNP.

127 he phenotype of yeast deficient in Vms1, the yeast homologue of ANKZF1.

128 When expressed in yeast, human Eps15 localized to the plasma membrane, whe

129 ing three example separations: live and dead yeast; human cancer cells/red blood cells; and rodent fi

130 e the accuracy and workflow of bacterial and yeast ID and bacterial AST using the Accelerate Pheno sy

131 Here we study budding yeast in dynamic environments of hyperosmotic stress and

132 shown to activate the S-phase checkpoint in yeast in response to replicative stress, but whether thi

133 The role played by yeasts in natural environments as well as in artificial

134 Systematic profiling of ex vivo (in yeast), in vitro, and in vivo activities of type-2 diacy

135 f transcriptome sequencing data from budding yeast, in high temporal resolution over ca. 2.5 cycles o

136 e most mutations showed similar behaviors in yeast, in vitro, and in Drosophila, a few showed anomalo

137 This work demonstrates that yeast involved in wine making, i.e. Saccharomyces cerevi

138 ontroversial, however, whether mammalian and yeast IRE1 use a common mechanism for ER stress sensing.

139 Yeast is a powerful model for systems genetics.

140 source of transcription-associated damage in yeast is Topoisomerase I (Top1), an enzyme that removes

141 low-pH environment of toxin-secreting killer yeasts, K28 is structurally stable and biologically acti

142 he forces that ensembles of purified budding yeast kinesin-5 Cin8 produce in microtubule gliding assa

143 We discovered that in budding yeast, kinetochore inactivation occurs by reducing the a

144 kinetochore proteins Nkp1 and Nkp2, from the yeast Kluyveromyces lactis, with nanoflow electrospray i

145 , we find that Stu1 recruits Stu2 to budding yeast KTs, which promotes MT generation there.

146 One example occurred when yeast lacking RAD1 were exposed to cisplatin, and we cha

147 Yeast lacking SGS1 accumulate R-loops and gamma-H2A at s

148 chromatin-remodeling network, as judged by a yeast-like nucleosome repeat length.

149 hogen, typically found as a benign commensal yeast living on skin and mucosa, but poised to invade in

150 ht underlie a cell differentiation switch in yeast mating response.

151 This yeast may grow freely in body fluids, but it also flouri

152 Non-Saccharomyces yeasts may contribute to enrich wine aroma while promoti

153 istant ability was stronger than that of the yeast mbf1.

154 In budding yeast meiosis, homologous chromosomes become linked by c

155 Yeast metabolites such as acetaldehyde and pyruvate part

156 The yeast Metschnikowia reukaufii produced distinctive compo

157 contrast, distinct pathways activate fission yeast Mga2 and Sre1.

158 on microscopy, Bim1 causes the compaction of yeast microtubules and induces their rapid disassembly.

159 Here we show that the budding yeast mismatch repair related MutLbeta complex, Mlh1-Mlh

160 We analyzed outer membrane fractions of yeast mitochondria and identified four new channel activ

161 genomes and provides concrete evidence that yeast mitochondria lack mechanisms for removal of ribonu

162 average error rates of T7 RNAP (2 x 10(-6)), yeast mitochondrial Rpo41 (6 x 10(-6)), and human mitoch

163 o counteracts Mdm30-mediated turnover of the yeast mitofusin Fzo1 and that Mdm30 targets Ubp2 for deg

164 o be widespread and dynamically regulated on yeast mRNA, but less is known about Psi presence, regula

165 rescues the Mn-hypersensitivity of the pmr1 yeast mutant but only slightly alleviates the Zn sensiti

166 leviates the Zn sensitivity of the zrc1 cot1 yeast mutant.

167 ta subunit and the RNR catalytic activity in yeast mutants depleted of individual components of the m

168 f these LDs, we screened approximately 6,000 yeast mutants for loss of targeting of the subpopulation

169 itiation at near-cognate UUG start codons in yeast mutants in which UUG selection is abnormally high.

170 nant proteins or by their complementation of yeast mutants.

171 In yeast, mutants defective in sterol biosynthesis show a w

172 covered that the myosin I protein in fission yeast, Myo1, which is required for organization of stero

173 Yeast Nop15 is an RRM protein that is essential for larg

174 ines spatial organization within the budding yeast nucleus, demonstrates the conserved role of genome

175 loyed a gene-centered approach utilizing the yeast one-hybrid assay to generate a network of protein-

176 localized SbSUT4 could not be detected using yeast or X. laevis oocytes.

177 es the recruitment of Atg17 complexes to the yeast PAS, and their unusual shape.

178 us organisms ranging from bacteria to algae, yeasts, plants, crustaceans and fish such as salmon.

179 Boi1 and Boi2 (Boi1/2) are budding yeast plasma membrane proteins that function in polarize

180 In budding yeast, polarization is associated with a focus of Cdc42*

181 ds that the first-step mutations selected in yeast populations evolving in parallel in the presence o

182 ce pattern of prions and eliminate them from yeast populations.

183 rate that akin to mammalian cells, wild-type yeast possess only two TRAPP complexes, TRAPPII and TRAP

184 ng as a crucial step in the formation of the yeast prion [PSI (+)], formed by the translation termina

185 described ability of Cur1 to antagonize the yeast prion [URE3], it enhances propagation and phenotyp

186 high amino acid compositional similarity to yeast prion domains.

187 rones and other cellular components cure the yeast prions [PSI(+)] (formed by Sup35p) or [URE3] (base

188 The yeast prions [PSI+] and [URE3] are folded in-register pa

189 We apply the technology to yeast prions, developing sensors to track their aggregat

190 We found that human, fly, and yeast profilin homologs all directly enhance microtubule

191 It has been proposed that many yeast promoters are not nucleosome-free but instead occu

192 We find that yeast promoters are predominantly bound by non-histone p

193 tial, we previously interrogated the budding yeast proteome to identify candidates that function in t

194 st of genes important for meiosis in fission yeast, providing a valuable resource to advance our mole

195 Yeast Prx1 is a mitochondrial 1-Cys peroxiredoxin that c

196 itro Therefore, here we assessed whether the yeast Pry1 protein binds fatty acids.

197 Although budding yeast Rad51 has been extensively characterized in vitro,

198 Here, we identify new fission yeast regulatory lncRNAs that are targeted, at their sit

199 codes the central strand exchange protein in yeast required for conservative HR.

200 ere we show that Y1F substitution in budding yeast resulted in a strong slow-growth phenotype.

201 Feeding A. aegypti with the engineered yeasts resulted in silenced target gene expression, disr

202 Here we report high-resolution structures of yeast Rev1 with three BP-N (2)-dG adducts, namely the 10

203 Heterologous expression of TmELO genes in yeast revealed that TmELO1 and TmELO2 function to synthe

204 Yeast ribosomal protein Rps3/uS3 resides in the mRNA ent

205 se-grained mathematical model of the fission yeast ring to explore essential consequences of the rece

206 We extend our technology to yeast RNA-binding proteins (RBPs) by tracking their prop

207 amine the function of Swi1 and Swi3, fission yeast's primary FPC components, to elucidate how replica

208 uction of salidroside can be achieved in the yeast Saccharomyces cerevisiae as well as the plant Nico

209 ss-response element in gene promoters in the yeast Saccharomyces cerevisiae However, the roles of Msn

210 The yeast Saccharomyces cerevisiae is consequently thought t

211 Under aerobic conditions, the budding yeast Saccharomyces cerevisiae metabolizes glucose predo

212 evels of endogenous hydrogen peroxide in the yeast Saccharomyces cerevisiae promote site-specific end

213 structures at up to 2.6 A resolution of the yeast Saccharomyces cerevisiae separase-securin complex.

214 4 subunit of the ubiquitin ligase GID in the yeast Saccharomyces cerevisiae targeted the gluconeogeni

215 ear microtubule (MT) dynamics in the budding yeast Saccharomyces cerevisiae This activity requires in

216 In the budding yeast Saccharomyces cerevisiae, ECM remodeling refers to

217 In the yeast Saccharomyces cerevisiae, the exposure to mating p

218 In the yeast Saccharomyces cerevisiae, the Opi1p repressor cont

219 In budding yeast Saccharomyces cerevisiae, the ten-subunit Dam1/DAS

220 In the yeast Saccharomyces cerevisiae, this inner membrane comp

221 antitative attributes of PKA dynamics in the yeast Saccharomyces cerevisiae, we developed an optogene

222 This cannot apply to the yeast Saccharomyces cerevisiae, where this mechanism wou

223 cation in trans of genomic or DI RNAs in the yeast Saccharomyces cerevisiae.

224 SAturated Transposon Analysis in Yeast (SATAY) allows one-step mapping of all genetic loc

225 o PKC orthologs Pck1 and Pck2 in the fission yeast Schizosaccharomyces pombe operate in a redundant f

226 ent-binding proteins (SREBPs) in the fission yeast Schizosaccharomyces pombe regulate lipid homeostas

227 In the fission yeast Schizosaccharomyces pombe, the CaMKK-like protein

228 In the fission yeast Schizosaccharomyces pombe, the protein kinase Cdr1

229 totic chromosome condensation in the fission yeast Schizosaccharomyces pombe.

230 and intrinsic reproductive isolation in the yeast Schizosaccharomyces pombe.

231 In mammals and yeast, several PMPs traffic via the ER in a Pex3- and Pe

232 ic complementation of glycolate transport in yeast showed that BASS6 was capable of glycolate transpo

233 commonly misidentified as several different yeast species by commercially available phenotypic ident

234 r enormous evolutionary diversity (there are yeast species in every subphylum of Dikarya) sparked cur

235 vage and polyadenylation sites (PASs) in two yeast species, S. cerevisiae and S. pombe Although >80%

236 reconstructed ancestral genomes and present yeast species.

237 We demonstrate here that a yeast-specific C-terminal region from Pat1 interacts wit

238 ing centers (MTOCs; mammalian centrosome and yeast spindle pole body [SPB]) nucleate more astral micr

239 he cryo-electron microscopy structure of the yeast SSU processome at 5.1-angstrom resolution.

240 cued the K(+) -uptake-defective phenotype of yeast strain CY162, suppressed the salt-sensitive phenot

241 Using a yeast strain expressing two Cdc20 genes with different e

242 , suppressed the salt-sensitive phenotype of yeast strain G19, and complemented the low-K(+) -sensiti

243 In this study, a total of 30 yeast strains belonging to the genera Dipodascus, Galact

244 Yeast strains defective in endosomal trafficking or orga

245 ative de novo mutations failed to complement yeast strains lacking the EEF1A ortholog showing a major

246 This strategy is demonstrated in yeast strains that show significantly enhanced heterolog

247 The newly isolated yeast strains were obtained by spontaneous fermentation

248 ce for the establishment and manipulation of yeast strains with the Sup35 prion.

249 a 25% improvement over previously engineered yeast strains.

250 ion of MS is a unique feature of respiratory yeasts such as P. pastoris and C. albicans, and it may h

251 variant and levoglucosan kinase (LGK) using yeast surface display (YSD) screening and a twin-arginin

252 cular, this protein will enable mirror-image yeast surface display experiments to identify all-d pept

253 ented with an experimental platform based on yeast surface display for affinity and specificity scree

254 , we integrated a computational method and a yeast surface display technique to obtain highly specifi

255 also be generally applicable to any type of yeast surface expressible DNA-binding protein.

256 fore, knowledge from the budding and fission yeast systems illuminates highly conserved molecular mec

257 We have shown previously in yeast that chronic VPA treatment induces the unfolded pr

258 Rhodotorula (Rhodosporidium) toruloides is a yeast that naturally synthesizes substantial amounts of

259 hat acts to kill gametes (known as spores in yeast) that do not inherit the gene from heterozygotes.

260 In budding yeast, the 3' end processing of mRNA and the coupled ter

261 In yeast, the ERMES complex is an endoplasmic reticulum (ER

262 nd shift assays, fluorescence Job plots, and yeast three-hybrid assays, we investigate the interactio

263 he endogenous cellular regulatory network of yeast to enhance compatibility with synthetic protein an

264 f homologous chromosomes during meiosis from yeast to humans, plays important roles in promoting inte

265 nd quorum sensing molecule that prevents the yeast to hyphal conversion.

266 kinase and this regulation is conserved from yeast to mammalian cells.

267 pair pathways that are highly conserved from yeast to mammals.

268 in kinase (MAPK) pathways are conserved from yeast to man and regulate a variety of cellular processe

269 investigate the adaptive response of budding yeast to temporally controlled H2O2 stress patterns.

270 ex from cleavage, and this has been shown in yeasts to be mediated by recruitment of the protein phos

271 y multiplexed barcode sequencing to identify yeast toxicity modifiers.

272 report the crystal structure of the fission yeast Tpz1(475-508)-Poz1-Rap1(467-496) complex that prov

273 asure the global RNA-binding dynamics of the yeast transcription termination factor Nab3 in response

274 Leveraging the extensive knowledge of yeast transcriptional regulation, we uncovered significa

275 Here, we show how the s(2) modification in yeast tRNA(Lys) affects mRNA decoding and tRNA-mRNA tran

276 assembled in vitro from mammalian or budding yeast tubulin.

277 istone deacetylase subunits were observed in yeast two-hybrid and bimolecular fluorescence assays, co

278 RNA-seq and proteomics data together with yeast two-hybrid assays suggest that MS23 along with MS3

279 Furthermore, using a yeast two-hybrid screen, we identified the motor protein

280 Using yeast two-hybrid, GST pull-down, co-immunoprecipitation

281 Here, we report the cryoEM structure of yeast U1 snRNP at 3.6 A resolution with atomic models fo

282 econstitute post-transcriptional assembly of yeast U6 snRNP in vitro, and propose a model for U6 snRN

283 d time-resolved metabolomics measurements in yeast under salt and pheromone stimulation and developed

284 ocol is based on a method developed to study yeast vacuolar fusion.

285 effectors that appear to be able to regulate yeast vacuolar fusion.

286 The assembly of yeast vacuolar SNAREs into complexes for fusion can be s

287 ently determined a cryo-EM reconstruction of yeast Vo The structure indicated that, when V1 is releas

288 Yeast Vps13 is involved in vacuolar protein transport an

289 stigation, Saccharomyces cerevisiae (baker's yeast) was engineered to produce short hairpin RNAs (shR

290 dies are motivated by the mating response of yeast, we believe our results and simulation methods wil

291 Using a combinatorial screen in yeast, we engineered an optogenetic biosensor, GIBBERELL

292 pring representation of chromatin in budding yeast, we find enrichment of protein-mediated, dynamic c

293 Applying this approach to yeast, we identified the circuit dominating cell cycle t

294 his assay to over 1,500 promoter variants in yeast, we reveal pronounced differences in the dependenc

295 main eisosome BAR-domain protein in fission yeast, we visualized whole eisosomes and, after photoble

296 Analogous binding, toxicity and rescue in yeast were observed.

297 We have found that Def1 copurifies from yeast whole-cell extract with TFIIH, the largest general

298 Saccharomyces cerevisiae is a common yeast with several applications, among which the most an

299 al membrane AAA+ quality control protease in yeast, YME1.

300 nteraction studies further demonstrated that yeast yUtp23 and human hUTP23 directly interact with the